Test bank for Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 8th Edition by Nader Rifai, PhD Chapters 1 - 49 2025/2026

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Test bank for Tietz Fundamentals of Clinical Chemistry
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and Molecular Diagnostics 8th Edition
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by Nader Rifai, PhD Chapters 1 - 49
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Tietz gFundamentals gof gClinical gChemistry gand gMolecular gDiagnostics g8th g Edition gTest
g Bank


Table gof gcontents:
I. gPrinciples gOf gLaboratory gMedicine
Chapter g1. gClinical gChemistry, gMolecular gDiagnostics, gand gLaboratory gMedicine
Chapter g2. gSelection gand gAnalytical gEvaluation gof gMethods g— gWith gStatistical gTechniques
Chapter g3. gClinical gEvaluation gof gMethods
Chapter g4. gEvidence-Based gLaboratory gMedicine
Chapter g5. gEstablishment g and gUse gof gReference gValues
Chapter g6. gSpecimen gCollection, gProcessing, gand gOther gPreanalytical gVariables
Chapter g7. gQuality gManagement
II. gAnalytical gTechniques gAnd gInstrumentation
Chapter g8. gPrinciples gof gBasic gTechniques gand gLaboratory gSafety
Chapter g9. gOptical gTechniques
Chapter g10. gElectrochemistry gand gChemical gSensors
Chapter g11. gElectrophoresis
Chapter g12. gChromatography
Chapter g13. gMass gSpectrometry
Chapter g14. gEnzyme gand gRate gAnalyses
Chapter g15. gImmunochemical gTechniques
Chapter g16 gAutomation
Chapter g17. gPoint-of-Care gInstrumentation
III. g gAnalytes
Chapter g18. gAmino g Acids, gPeptides, gand gProteins
Chapter g19. gSerum gEnzymes
Chapter g20. gTumor gMarkers gand gCancer gGenes
Chapter g21. gKidney gFunction gTests g— gCreatinine, gGFR, gUrea, gand gUric gAcid
Chapter g22. gCarbohydrates
Chapter g23. gLipids, gLipoproteins, gApolipoproteins, g and gOther gCardiac gRisk gFactors
Chapter g24. gElectrolytes gand gBlood gGases
Chapter g25. gHormones
Chapter g26. g Catecholamines gand gSerotonin
Chapter g27. g gVitamins, gTrace gElements, gNutritional gAssessment
Chapter g28. gHemoglobin, gIron, gand gBilirubin
Chapter g29. gPorphyrins gand gPorphyrias
Chapter g30. gTherapeutic gDrugs gand gTheir gManagement
Chapter g31. gClinical gToxicology
Chapter g32. g Toxic gMetals
IV. g gPathophysiology
Chapter g33. gDiabetes

,Chapter g34. g Cardiovascular gDisease
Chapter g35. gKidney gDisease
Chapter g36. g Physiology gand gDisorders gof gWater, gElectrolyte, gand gAcid-Base gMetabolism
Chapter g37. g gLiver gDisease
Chapter g38. g Gastrointestinal gand gPancreatic gDiseases
Chapter g39. g gDisorders gof gBone gand gMineral gMetabolism
Chapter g40. g gDisorders gof gthe gPituitary gGland
Chapter g41. g Disorders gof gthe gAdrenal gCortex
Chapter g42. g Thyroid gDisorders
Chapter g43. g Reproduction-Related gDisorders
Chapter g44. g gPregnancy gand gPrenatal gTesting
Chapter g45. g Newborn gScreening gand gInborn gErrors gof gMetabolism
Chapter g46. gPharmacogenetics
V. g gMolecular gDiagnostics
Chapter g47. gPrinciples gof gMolecular gBiology
Chapter g48. gNucleic gAcid gTechniques gand gApplications
Chapter g49. gGenomes gand gNucleic gAcid gAlterations

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Chapter g01: gClinical gChemistry, gMolecular gDiagnostics, gand gLaboratory gMedicine
g TestBank




MULTIPLE gCHOICE

1. An gindividual gworking gin ga gclinical gchemistry glaboratory gis gmarried gto ga gsales grepresentative
g who gworks gfor ga gcompany gthat gsells gchemistry glaboratory gsupplies. gWhen gthe glaboratory
g manager g requests ga glist g of gneeded gsupplies, g cost gof gsupplies, g and gvendors, gthis g individual

gonly g recommends gthe gspouse’s gcompany gas gthe gvendor. gThis gis gconsidered g to gbe ga(n):

a. accounting gissue.
b. possible gconflict gof ginterest.
c. maintenance gof gconfidentiality gissue.
d. problem gwith gresource gallocation.

ANS: g B
Concern ghas gbeen graised gover gthe ginterrelationships gbetween gpractitioners gin gthe gmedical gfield
g and gcommercial gsuppliers gof gdrugs, g devices, g equipment, g etc., gto gthe gmedical gprofession.

Similarly, grelationships ghave gbeen gscrutinized gbetween gclinical glaboratorians gand g manufacturers
gand gproviders gof gdiagnostic gequipment g and gsupplies. g These gconcerns g led gthe g National

gInstitutes gof gHealth g(NIH) gin g1995 gto grequire gofficial ginstitutional greview gof gfinancial

g disclosure gby gresearchers gand g management g of gsituations g in gwhich gdisclosure gindicates gpotential

g conflicts gof ginterest.



DIF: 1 REF: g g gPage g4-5 OBJ: g 6 g| g7

2. A gpatient gvisits gher gphysician gstating gthat gher gprescribed gpainkiller gis gnot g working gto greduce
g the gpain gfollowing gher grecent gsurgery. gA gfriend gof gthe gpatient gclaims gthat gthe gsame
gpainkiller g “worked gwonders” gto greduce gher gpain gafter gthe gsame gsurgery. g The gphysician

gstates gthat gthe g difference gin gthe geffect gof gthe gdrug gmight g be gcaused gby , g which gis gstudied

g in g pharmacogenetics.

a. epidemiology
b. an ginherited gdisease
c. a gconflict gof ginterest
d. a ggenetic gvariation gin gdrug-metabolizing genzymes
ANS: g D
Pharmacogenetics gis gthe gstudy gof gthe ggenetic gvariation gof gdrug gmetabolism gbetween
g individuals.



DIF: 1 REF: g g gPage g3 OBJ: g 1

3. John gworks gin ga gmolecular gdiagnostics glaboratory gand greceives ga gblood gsample gthat ghas gthe
g name gof ga gclose gfriend gprinted gon gthe gbar-coded glabel. gThe ggenetic gtest gthat gis gordered gon
gthe g friend’s gsample gwould gprovide gdiagnostic ginformation gabout ga gdisorder gthat ghas ga
gpoor g prognosis, g and gthe gtest g is gusually gperformed gby gJohn. g He gasks ga g fellow gemployee gto

ganalyze g the gsample g for ghim gand gnot gdivulge gthe gresults. g This gethical gissue gconcerns:

a. confidentiality gof gpatient ggenetic gand gmedical ginformation.
b. a gconflict gof ginterest.
c. resource gallocation.