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Terms in this set (83)
SSRIs
SNRIs
Medications for
SDRIs
depression
TCAs
MAOIs
-Action: inhibit 5-HT reuptake
-Examples: citalopram, escitalopram, fluoxetine,
paroxetine, sertraline
-Adverse effects:
• nausea
SSRIs
• agitation
• diarrhea
• headache
• weight gain
• sexual side effects
, -inhibit 5-HT reuptake
-inhibit NE reuptake (↑ energy, focus)
-increase DA in prefrontal cortex (↑ cognition)
-Examples: desvenlafaxine, duloxetine,
levomilnacipran, venlafaxine
-Adverse effects:
• elevated blood pressure
SNRIs • nausea
• sweating
• tremors
• anxiety
• insomnia
• constipation
• anorexia
• sexual dysfunction
-inhibit DA reuptake (↑alertness, motivation)
-inhibit NE reuptake (↑energy)
-Adverse effects:
• agitation
SDRIs
• headache
• dry mouth
• constipation
• weight loss
, -Action: inhibits the reuptake of serotonin and
norepinephrine; blocks norepinephrine, histamine,
and acetylcholine receptors
-Examples: amitriptyline, clomipramine, desipramine,
doxepin
-Common Side Effects:
• dry mouth
TCAs • constipation
• blurred vision
• urinary retention
• sedation
• weight gain
• hypotension
• tachycardia
• sexual dysfunction
-Action: increases norepinephrine and serotonin by
inhibiting the enzyme that inactivates it
-Examples: isocarboxazid, phenelzine,
tranylcypromine
MAOIs -Common Side Effects:
• sedation
• dizziness
• sexual dysfunction
• hypertensive crisis
Prescribing pearls: mild antihistamine effects
citalopram (Celexa)
Prescribing pearls: no known drug interactions
escitalopram (Lexapro)
Prescribing pearls: longest half-life
fluoxetine (Prozac)
Prescribing pearls: also treats social anxiety and insomnia
paroxetine (Paxil)