2025/l 2026l Update)l Geneticsl |l Questionsl
&l Answers|l Gradel A|l 100%l Correctl
(Verifiedl Solutions)-l Portagel Learning
Q:l Thel fusedl "Philadelphial chromosome"l inl myelogenousl leukemial isl
froml al mutatedl _______l gene.l
Answer:
BCR-ABL
Q:l Matchl thel termsl
Answer:
Driver:l mutationsl thatl impartl somel sortl ofl growthl advantagel
Steml cell:l Undifferentiatedl cells
Passenger:l mutationsl thatl dol notl contributel tol thel phenotype
Metastatic:l defectsl inl thel cellsl restraintsl thatl nol longerl keepl theml localized
Tumor:l solidl massl growth
, Q:l Usingl thel developmentl ofl colonl cancerl asl anl example,l explainl howl
thel processl ofl tumorigenesisl canl occurl inl distinctl stagesl throughl thel
accumulationl ofl mutations.l
Answer:
inl thel firstl stagel ofl colonl cancerl al polypl willl growl andl isl consideredl
benignl duel tol al defectl inl thel APCl gene.l Inl thel secondl stagel thel krasl
genel causesl issuesl inl thel adenomal .l thel krasl genel becomesl activel andl
celll growthl isl uncontrolledl andl manifestsl al largerl polyp.l Thenl inl thel thirdl
stagel thel adenomal becomesl al carcinomal whichl isl malignantl andl thel
carcinomal isl ablel tol movel andl invadel otherl tissuesl ofl differentl partsl ofl
thel body.
Q:l Mostl scientistsl believel thatl thel biggestl driverl ofl thel cancerl phenotypel
isl thel inabilityl ofl thel celll to:l
Answer:
Repair
Q:l Cellsl thatl havel maturedl tol providel al specificl functionl inl thel bodyl arel
calledl ___l
Answer:
Differentiatedl cells
Q:l Givel threel examplesl ofl differentiatedl cellsl thatl stilll divide.l