NAPLEX Immunizations
What are patients required to receive prior to vaccine administration, per Federal law? - Answer-the
most up-to-date Vaccine Information Statement (VIS)
What is active immunity? - Answer-protection produced by the person's own immune system; usually
permanent
- acquired by surviving an infection
- acquired by vaccination
What is passive immunity? - Answer-protection by antibody-containing products produced by an animal
or human and TRANSFERRED to a human; protection goes away in a few weeks to months
- usually given by injection
- also provided from mother to infant
What is an example of an antibody-containing product that provides passive immunity? - Answer-IV
immune globulin
If a patient receives a live vaccine first, how long must they wait before receiving an antibody? - Answer-
2 weeks
, If a patient receives an antibody first, how long must they wait before receiving a live vaccine? - Answer-
3 months or longer (up to 11 months)
**except Zoster vaccine, which is not affected by circulating antibody
When is it appropriate to administer antibody and vaccine simultaneously? - Answer-post-exposure
prophylaxis for certain disease (hep A, hep B, rabies, tetanus)
- note: the antibody must be an immune globulin
What does the CDC Advisory Committee on Immunization Practices (ACIP) state regarding the
simultaneous administration of live or inactivated vaccines? - Answer-There is NO contraindication to
simultaneous administration of any vaccines currently in the US
- does not ↑ antibody response
- does not ↑ rate of adverse reactions
- every effort should be made to provide all necessary vaccinations at one visit to improve compliance
What is the recommendation for live vaccines that COULD BE GIVE at the same visit but are not? -
Answer-separate by at least 4 weeks
- example: if live injected vaccine (MMR, MMRV, varicella, zoster, and yellow fever) and live intranasal
influenza vaccine (LAIV) are not administered at the same visit, they should be separated by at least 4
weeks.
What is a disadvantage of increasing the interval between doses of a multi-dose vaccine series? -
Answer-delays more complete protection
What is a disadvantage of decreasing the interval between doses of a multi-doses vaccine series? -
Answer-may interfere with antibody response and protection
A tuberculin skin test (TST) is performed by injecting _______ into the inner surface of the forearm. -
Answer-0.1 mL of tuberculin purified protein derivative (PPD)
What are patients required to receive prior to vaccine administration, per Federal law? - Answer-the
most up-to-date Vaccine Information Statement (VIS)
What is active immunity? - Answer-protection produced by the person's own immune system; usually
permanent
- acquired by surviving an infection
- acquired by vaccination
What is passive immunity? - Answer-protection by antibody-containing products produced by an animal
or human and TRANSFERRED to a human; protection goes away in a few weeks to months
- usually given by injection
- also provided from mother to infant
What is an example of an antibody-containing product that provides passive immunity? - Answer-IV
immune globulin
If a patient receives a live vaccine first, how long must they wait before receiving an antibody? - Answer-
2 weeks
, If a patient receives an antibody first, how long must they wait before receiving a live vaccine? - Answer-
3 months or longer (up to 11 months)
**except Zoster vaccine, which is not affected by circulating antibody
When is it appropriate to administer antibody and vaccine simultaneously? - Answer-post-exposure
prophylaxis for certain disease (hep A, hep B, rabies, tetanus)
- note: the antibody must be an immune globulin
What does the CDC Advisory Committee on Immunization Practices (ACIP) state regarding the
simultaneous administration of live or inactivated vaccines? - Answer-There is NO contraindication to
simultaneous administration of any vaccines currently in the US
- does not ↑ antibody response
- does not ↑ rate of adverse reactions
- every effort should be made to provide all necessary vaccinations at one visit to improve compliance
What is the recommendation for live vaccines that COULD BE GIVE at the same visit but are not? -
Answer-separate by at least 4 weeks
- example: if live injected vaccine (MMR, MMRV, varicella, zoster, and yellow fever) and live intranasal
influenza vaccine (LAIV) are not administered at the same visit, they should be separated by at least 4
weeks.
What is a disadvantage of increasing the interval between doses of a multi-dose vaccine series? -
Answer-delays more complete protection
What is a disadvantage of decreasing the interval between doses of a multi-doses vaccine series? -
Answer-may interfere with antibody response and protection
A tuberculin skin test (TST) is performed by injecting _______ into the inner surface of the forearm. -
Answer-0.1 mL of tuberculin purified protein derivative (PPD)
