Mechanisms:
Nucleophilic addition to carbonyls:
Sodium Borohydride Nabha B Organometallic Reagents R M reacting them
aldehydes ketones imines
Li iii a
HI
phot
t
r s
joy Mein
µ p if a the
Br
Mg
c Cyanide Reagents CN
no p
Na
fffff fff p sgff.gg
it
all give alcohols
Organometallic reagents:
Created via oxidative insertion
anm.gg halogen exchange
problem
solutiggingto
1 Br EE MgBr
y Nat By
t.pe
in B
2 a Lehane a trio
Organometallic rxn's w aldehyde O
iii
Br
i
on i.it
Formaldehyde Grignard 1 alcohol
Aldehyde Grignard 2 alcohol
IE aIigia9a dcaio
yiiihici RM9Br 7H30 o
canalsodo mn win coz not a
insteadof
p o MgBr
Nucleophilic addition to carbonyls:
Sodium Borohydride Nabha B Organometallic Reagents R M reacting them
aldehydes ketones imines
Li iii a
HI
phot
t
r s
joy Mein
µ p if a the
Br
Mg
c Cyanide Reagents CN
no p
Na
fffff fff p sgff.gg
it
all give alcohols
Organometallic reagents:
Created via oxidative insertion
anm.gg halogen exchange
problem
solutiggingto
1 Br EE MgBr
y Nat By
t.pe
in B
2 a Lehane a trio
Organometallic rxn's w aldehyde O
iii
Br
i
on i.it
Formaldehyde Grignard 1 alcohol
Aldehyde Grignard 2 alcohol
IE aIigia9a dcaio
yiiihici RM9Br 7H30 o
canalsodo mn win coz not a
insteadof
p o MgBr
