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Basic Bio-Chem (complete version)(BIO181)

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Unit 1 lectures 1-3, BIO 181, includes all content regarding chemistry for the course

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Basic Bio-Chemistry
why is chem important in Biology
Molecular composition and structure

Biochemical reactions

Enzyme function

Genetics and moleu;ar biology

cellular processes

drug development


Atoms
all life and matter are built from atoms

Number of electrons and proton sis generally the same

Proton/neutron in the center

surrounded by electron

Atoms have atomic number and mass number

Atomic number is number of protons

mass number is number of neutrons and protons

Isotopes

Form of an element with different numbers of neutrons, and thus different
mass numbers

somewhat unstable

can cause reactions

Radioisotopes

give off eneergy in form or radiation from the nucleous

—> leads to radioactive decay, changing number of neutrons over times



Basic Bio-Chemistry 1

, can cause mutations, leading to cancer, damage cell tissue

can also kill cancer cells (chemotherapy)

Biologically, electrons are the most important

determine chemical reactivity of each element

Orbital path of the electron define the geometry of the bonds

geometry of a conception of two elements to form a molecule is
determined largely by orbital structure (the way its shaped determines
how they interact with eachother)

Defines chemical reactivity of each substance

also determined by the distribution of electrons in their outer shell
(Valence)


Periodic table
Elements in the same periodic table, called a group or family, share the same
number of electrons in their outer shell

chemical bonds form when atoms interact to complete their valance (outer)
shell, bond type depends on electronegativity (their ability to attract electrons)

Alkalai metals & earth metals: very reactive

Bottom left, less elecrtonegativity

top right, more electronegativity

Except for noble gasses because they only need one more


Intramolecular & Intermolecular interactions

https://www.researchgate.net/publication/369676537/figure/fig2/AS:114312
81133902078@1680322441693/Classification-of-intermolecular-and-intram
olecular-forces-Figure-was-taken-from-Ref.ppm




Basic Bio-Chemistry 2

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January 12, 2025
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