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NR565/NR 565 - advanced pharmacology care of the fundamentals real midterm Exam verified & graded A+|2024 Updated

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What is BEERS criteria? Answer Recommendations of medications inappropriate for the elderly (65 and older), the prescriber ultimately decides What is the CYP450 (cytochrome P450) liver enzyme system where medications are metabolized, can either be inducers or inhibitors and create drug-drug interactions CYP450 inducers Speed up metabolism of drugs (drug is cleared faster), drug has lesser effect (decrease blood levels of drug), elevate CYP450 enzymes CYP450 inducers pneumonic "Bullshit Crap GPS INDUCES rage" CYP450 inducer drug names Barbituates, St John wort, Carbamazepine, rifampin, alcohol, phenytoin, griseofulvin, phenobarbital, sulfonylureas CYP450 inhibitors inhibit metabolism, increase blood levels of medications CYP450 pneumonic "VISA credit card debt INHIBITS spending on designers like CK to look GQ" CYP450 inhibitors drug names Valproate, isoniazid, sulfonamides, amiodarone, chloramphenicol, ketoconazole, grapefruit juice, quinidine Physiological changes during pregnancy that impact pharmacodynamics and pharmacokinetic properties of drugs? Answer increase glomerular filtration rate leads to increased drug excretion increase hepatic metabolism decrease tone and motility of the bo

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NR565/NR 565 -
advanced pharmacology
care of the fundamentals
real midterm Exam
verified & graded A+|
2024 Updated
What is BEERS criteria? Answer✓✓
Recommendations of medications inappropriate for the elderly (65 and older), the
prescriber ultimately decides




What is the CYP450 (cytochrome P450)
liver enzyme system where medications are metabolized, can either be inducers or
inhibitors and create drug-drug interactions




CYP450 inducers
Speed up metabolism of drugs (drug is cleared faster), drug has lesser effect
(decrease blood levels of drug), elevate CYP450 enzymes




CYP450 inducers pneumonic
"Bullshit Crap GPS INDUCES rage"

,NR565/NR 565 -
advanced pharmacology
care of the fundamentals
real midterm Exam
verified & graded A+|
2024 Updated
CYP450 inducer drug names
Barbituates, St John wort, Carbamazepine, rifampin, alcohol, phenytoin, griseofulvin,
phenobarbital, sulfonylureas




CYP450 inhibitors
inhibit metabolism, increase blood levels of medications




CYP450 pneumonic
"VISA credit card debt INHIBITS spending on designers like CK to look GQ"




CYP450 inhibitors drug names
Valproate, isoniazid, sulfonamides, amiodarone, chloramphenicol, ketoconazole,
grapefruit juice, quinidine

,NR565/NR 565 -
advanced pharmacology
care of the fundamentals
real midterm Exam
verified & graded A+|
2024 Updated
Physiological changes during pregnancy that impact pharmacodynamics and
pharmacokinetic properties of drugs? Answer✓✓
increase glomerular filtration rate leads to increased drug excretion
increase hepatic metabolism
decrease tone and motility of the bowel
increase drug absorption




Examples of medications that can be teratogenic
Antiepileptic drugs, antimicrobials such as tetracyclines and fluoroquinolones,
vitamin A in large doses, some anticoagulants, and hormonal medications such as
diethylstilbestrol (DES).




How is absorption of intramuscular medications different in neonates? Answer✓✓
slow and erratic due to low blood flow in muscles first few days of life




Why is absorption of medication in the stomach increased in infancy? Answer✓✓
delayed gastric emptying

, NR565/NR 565 -
advanced pharmacology
care of the fundamentals
real midterm Exam
verified & graded A+|
2024 Updated

Some medications that should be avoided in the pediatric patient? Answer✓✓
glucocorticoids, discoloration of developing teeth with tetracyclines, and kernicterus
with sulfonamides, levofloxacin (antibiotics)
aspirin (Severe intoxication from acute overdose)




what should be included in medication administration patient education? Answer✓✓
dosage size and timing
route and technique of administration
duration of treatment
drug storage
nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic

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