The following laboratory data were obtained from a 27-year-old man with a
long history of abnormal bleeding:
prothrombin time: normal
activated partial thromboplastin time: markedly
prolonged Factor VIII coagulant activity: markedly
decreased
Factor VIII related antigen:
normal platelet count: normal
template bleeding time:
normal correct answers
classic hemophilia
A hemophiliac male and a normal female can produce a: correct
answers female carrier
The following laboratory data were obtained from a 40-year-old woman
with a long history of abnormal bleeding:
prothrombin time: normal
activated partial thromboplastin time:
prolonged Factor VIII coagulant activity:
decreased
Factor VIII related antigen: markedly
decreased platelet count: normal
template bleeding time: prolonged
correct answers von Willebrand disease
Which of the following factor deficiencies is associated with either no
bleeding or only a minor bleeding tendency, even after trauma or surgery?
correct answers Factor XII
The most potent plasminogen activator in the contact phase of coagulation
is: correct answers kallikrein
Acute disseminated intravascular coagulation is characterized by:
correct answers hypofibrinogenemia
A patient has a normal prothrombin time and a prolonged activated partial
thromboplastin time (APTT) using a kaolin activator. The APTT corrects to
normal when the incubation time is increased. These results suggest that the
patient has: correct answers Fletcher Factor deficiency (prekallikrein)
Aliquots of plasma with a prolonged PT and prolonged APTT are mixed using
various ratios of patient plasma and normal plasma. All samples are
incubated at 37°C and tested at 10-, 30-, and 60-minute intervals. The PT
and APTT results on all of the mixtures are corrected. These results would
indicate the presence of: correct answers factor deficiency
, A 53-year-old man was in recovery following a triple bypass operation.
Oozing was noted from his surgical wound. The following laboratory data
were obtained: Hemoglobin: 12.5 g/dL (125 g/L)
Hematocrit: 37%
Prothrombin time: 12.3
seconds APTT: 34 seconds
Platelet count: 40.0 x 103/µL (40.0x
109/L) Fibrinogen: 250 mg/dL (2.5
g/L)
The most likely cause of bleeding would be: correct answers
dilutional thrombocytopenia
Which of the following is characteristic of platelet disorders? correct
answers mucous membrane hemorrhages
Which of the following is most closely associated with acute promyelocytic
leukemia? correct answers disseminated intravascular coagulation
Which of the following is true of acute lymphoblastic leukemia (ALL)?
correct answers massive accumulation of primitive lymphoid-appearing
cells in bone marrow occurs
The atypical lymphocyte seen in the peripheral smear of patients with
infectious mono is probably derived from which of the following? correct
answers B lymphocytes
A patient has a tumor that concentrates erythropoietin. He is most likely to
have which of the following types of polycythemia? correct answers
polycythemia associated with renal disease
Which of the following conditions is not associated with a high incidence of
leukemia? correct answers megaloblastic anemia
Which of the following is most closely associated with chronic
myelomonocytic leukemia? correct answers lysozymuria
In comparison to malignant lymphoma cells, reactive lymphocytes: correct
answers are morphologically more variable throughout the smear
Of the following, the disease most closely associated with
mucopolysaccharidosis is: correct answers Alder-Reilly anomaly
An anemic patient has an RBC of 2.70 x 106/µL (2.7 x 1012/L) and a
hemoglobin of
13.5 g/dL (135 g/L) as determined by an electronic particle counter.
Which of the following is the best explanation for these results?
correct answers lipemia
Refer to the following illustration:
Which area in the automated cell counter histogram represents the platelet
distribution curve? correct answers E