Obesity Exam 3| Questions with 100%
Correct Solution| Rated A
With caloric restriction and weight loss:
Starvation/survival mode decreases _______________________ and increases
___________________ - ANSWER - decreases leptin, EE, reproductive capacity
- increases appetite
With caloric intake and weight gain:
Normal mode increases ______________ and decreases _____________ - ANSWER - increases
leptin
- decreases appetite
With caloric intake and weight gain:
Obese mode = ? - ANSWER leptin deficiency
(T or F) Lean mice had the same response to leptin treatment as obese mice - ANSWER False,
lean mice did not have as strong of a response
Leptin Dose Response on Weight in Humans - ANSWER - only some subjects induced weight
loss w/ elevated endogenous leptin serum concentrations
In order for treatment to be effective more __________ is needed w/ more _____________ -
ANSWER - leptin
, - adiposity
Trend of high fructose corn syrup consumption - ANSWER - rapid increase since 1966
Leptin treatment reduced food intake in _______________________ but not in
____________________ - ANSWER - normal fed mice
- high fructose fed mice
Adiponectin - ANSWER - peptide secreted by fat cells
- regulates glucose
- low levels associated w/ atherosclerosis and impaired immune response
Low levels of _______________________ are associated w/ atherosclerosis and impaired
immune response - ANSWER adiponectin
Obesity can lead to resistance of __________________& ________________ - ANSWER
adiponectin and insulin
Levels of Adiponectin (obese vs lean) - ANSWER Obese = low
Lean = high
Levels of Resistin (obese vs lean) - ANSWER Obese = high
Lean = low
Levels of TNF-alpha (obese vs lean) - ANSWER obese =
high lean = low
Levels of IL-6 (obese vs lean) (peripheral system vs. CNS) - ANSWER Peripheral system:
Correct Solution| Rated A
With caloric restriction and weight loss:
Starvation/survival mode decreases _______________________ and increases
___________________ - ANSWER - decreases leptin, EE, reproductive capacity
- increases appetite
With caloric intake and weight gain:
Normal mode increases ______________ and decreases _____________ - ANSWER - increases
leptin
- decreases appetite
With caloric intake and weight gain:
Obese mode = ? - ANSWER leptin deficiency
(T or F) Lean mice had the same response to leptin treatment as obese mice - ANSWER False,
lean mice did not have as strong of a response
Leptin Dose Response on Weight in Humans - ANSWER - only some subjects induced weight
loss w/ elevated endogenous leptin serum concentrations
In order for treatment to be effective more __________ is needed w/ more _____________ -
ANSWER - leptin
, - adiposity
Trend of high fructose corn syrup consumption - ANSWER - rapid increase since 1966
Leptin treatment reduced food intake in _______________________ but not in
____________________ - ANSWER - normal fed mice
- high fructose fed mice
Adiponectin - ANSWER - peptide secreted by fat cells
- regulates glucose
- low levels associated w/ atherosclerosis and impaired immune response
Low levels of _______________________ are associated w/ atherosclerosis and impaired
immune response - ANSWER adiponectin
Obesity can lead to resistance of __________________& ________________ - ANSWER
adiponectin and insulin
Levels of Adiponectin (obese vs lean) - ANSWER Obese = low
Lean = high
Levels of Resistin (obese vs lean) - ANSWER Obese = high
Lean = low
Levels of TNF-alpha (obese vs lean) - ANSWER obese =
high lean = low
Levels of IL-6 (obese vs lean) (peripheral system vs. CNS) - ANSWER Peripheral system:
