PCB 3233 Exam 5 questions well answered to pass

PCB 3233 Exam 5

What are the cells that can become plasma cells? - correct answer ✔✔Memory B Cells, Activated B Cells,
& Isotype-switched, somatically hypermutated centrocytes



What are the components of the B cell co-receptor (CR2 is one of them) - correct answer ✔✔CR2 binds
to complement deposited on the pathogen - The secondary check point for B cell activation

CD19 - Receptor signaling

CD81/TAPA-1 -Binds to CD19 and is essential and bringing it to the B cell surface.



What is CR2 and it's purpose? - correct answer ✔✔Binds to complement deposited on the pathogen -
The secondary check point for B cell activation.



What is CD19 and it's purpose? - correct answer ✔✔Receptor signaling



What is CD81/TAPA-1 and it's purpose? - correct answer ✔✔Binds to CD19 and is essential and bringing
it to the B cell surface.



What does CR1 do for the co-receptor? - correct answer ✔✔CR1 binding to C3b on a pathogen facilitates
the cleavage by factor I to ic3b and C3d. Then, the CR2 component of the B-cell co-receptor binds to C3d.



What does TI antigen mean? - correct answer ✔✔TI stands for Thymus Independent. They activate
production of B cells without T lymphocyte involvement



What makes TI antigen different from DT antigens? - correct answer ✔✔TD antigens are Thymus
Dependent AGs.

Bulk of pathogen specific AB are produced by TD Ags.

TD Ags activate B cells in secondary lymphoid tissues.