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BIO 436 Final Exam Questions and Correct Answers- SDSU

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What does hematocrit measure? percentage of red blood cells in the blood Normal hematocrit for males 42-52% Why do males have a higher hematocrit? Males have higher levels of testosterone which stimulates the release of erythropoietin Normal hematocrit for females 37-47% What can be determined from a person's hematocrit? dehydration, blood disorder, anemia, polycythemia, other conditions Polycythemia hematocrit of 70% or more Anemia hematocrit of 30% or less Iron deficiency anemia - not enough iron - body can't make hemoglobin - O2 can't get transported Aplastic anemia failure of bone marrow to produce adequate RBC numbers Pernicious anemia lack of B12 Hemolytic anemia rbcs are destroyed and removed from the bloodstream before their normal lifespan is over Sickle cell anemia - inherited condition - protein portion of hemoglobin molecule folds incorrectly - O2 can't bind to Hb - rbcs misshapen What does ESR stand for? erythrocyte sedimentation rate Can ESR be used to diagnose diseases? - no, just to track progression - sickle cell, some cancers, RA How long do mature RBC's survive? 120 days

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BIO 436 Final Exam Questions and
Correct Answers- SDSU
What does hematocrit measure? ✅percentage of red blood cells in the blood

Normal hematocrit for males ✅42-52%

Why do males have a higher hematocrit? ✅Males have higher levels of testosterone
which stimulates the release of erythropoietin

Normal hematocrit for females ✅37-47%

What can be determined from a person's hematocrit? ✅dehydration, blood disorder,
anemia, polycythemia, other conditions

Polycythemia ✅hematocrit of 70% or more

Anemia ✅hematocrit of 30% or less

Iron deficiency anemia ✅- not enough iron
- body can't make hemoglobin
- O2 can't get transported

Aplastic anemia ✅failure of bone marrow to produce adequate RBC numbers

Pernicious anemia ✅lack of B12

Hemolytic anemia ✅rbcs are destroyed and removed from the bloodstream before
their normal lifespan is over

Sickle cell anemia ✅- inherited condition
- protein portion of hemoglobin molecule folds incorrectly
- O2 can't bind to Hb
- rbcs misshapen

What does ESR stand for? ✅erythrocyte sedimentation rate

Can ESR be used to diagnose diseases? ✅- no, just to track progression
- sickle cell, some cancers, RA

How long do mature RBC's survive? ✅120 days

, How does the body replace rbcs? ✅Stem cells in bone marrow make more

What organ is responsible for the production of new rbcs and what hormone is
involved? ✅the kidneys: release EPO to tell bone marrow to make more

What is hemoglobin? ✅a protein containing iron

Where is hemoglobin found? ✅red blood cells

How does Hb help rbcs to carry O2 to tissues? ✅O2 binds to Hb on rbcs

What is blood typing? ✅determines which antigen is present on a person's rbcs

Which antigens can be found on rbcs ✅A, B, A&B, or none

Which antibodies can be found in the blood? ✅anti-A, anti-B, ant-A and anti-B, or none

What does blood type refer to? ✅the antigens present on the RBC's surface

Type A blood antigens/antibodies ✅A antigens and anti-B antibodies

Type B blood antigens/antibodies ✅B antigens and anti-A antibodies

Type AB blood antigens/antibodies ✅A and B antigens, no antibodies

Type O blood antigens/antibodies ✅no antigens, anti-A and anti-B antibodies

What happens if someone is given the wrong blood type? ✅- antibodies in recipient's
blood will attack donor blood cells and destroy them
- can cause a life-threatening reaction

How do our bodies transport cholesterol (along with some triglycerides and
phospholipids)? ✅- with lipoproteins
- cholesterol is hydrophobic and must be wrapped in lipoproteins in order to travel in the
bloodstream

What is the major organ responsible for synthesizing cholesterol for our bodies? ✅liver

What is chylomicron ✅the lipoprotein that transports cholesterol and lipids from the
intestines to the liver

What is HDL ✅- high density lipoprotein
- cholesterol from tissue to liver

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