How do Statins work? - ANSBlocks the enzyme responsible for the biosynthesis of cholesterol
Two potentially life-threatening adverse effects of Statins - ANSRhabdomyolysis and Liver
damage
**Check CPK (Creatine phosphokinase test) and LFT (Liver function test)**
What will patient complain of with Rhabdomyolysis? - ANSMuscle and joint pain
All cholesterol medications have what kind of adverse effects? - ANS**GI: diarrhea, nausea,
vomiting, constipation
Bile acid sequestrants (Questran), what form do they come in? - ANSPowdered form
-**Give with 4 oz of water**
What do you tell patients taking Bile acid sequestrants (Questran) about taking other
medications? - ANSTake 2 hrs before or 4 hrs after.
How does Niacin make us feel? - ANSFlushing feeling**
-To reduce take Aspirin
(Decreases LDL 20%)
Diuretics, when are they taken? - ANSIn the MORNING
How do diuretics work to reduce BP - ANSIncrease urine output, which decreases circulating
fluid volume
What do loop diuretics do to our potassium? - ANSDecrease
What do look diuretics do to our BP? - ANSDecrease
Calcium channel blockers, should patient increase calcium in diet? - ANSNO
Calcium channel cause vasodilatation, what does that do to us? - ANSGive headache
Most common adverse effect of ACE inhibitors - ANSDry hacking cough
Most life threatening adverse effect of ACE inhibitors - ANSAngioedema
, Digoxin - ANSCheck apical pulse for 60 sec. **
Hold less <60 **
High blood pressure - ANSFirst: Start with lifestyle modifications
-If that doesn't work, give diuretics, ACE inhibitors, and/ or beta blockers
What should you do when giving BP meds, before and after? - ANSCheck BP
BP low after starting new BP med, what do you do? - ANSDont worry, have patient call if they
have to get up to use the restroom so they don't FALL.
Do you get a cough with ARB? (Angiotensin receptor blocker) - ANSNO
Could you get Angioedema with ARB? (Angiotensin receptor blocker) - ANSYou can
What do ACE inhibitors do to our Potassium? - ANSIncreases
What do Beta Blockers do to our HR? - ANSSlow it down
What do Beta Blockers do to our BP? - ANSDecrease
Can someone with Asthma, COPD, or tracheal stricture take beta blockers? - ANSThey cannot
take BETA2 blockers (lungs)
What might happen to Potassium when taking DIgoxin? - ANSDecrease
What is the most important vital sign to check when giving Digoxin - ANSAPICAL PULSE
Labs to check when taking Digoxin? - ANSDigoxin and Potassium
Nitroglycerine - ANSTake Sublingual
-Take 3 x 5 min apart, then call 911 **
How do you prevent tolerance with Nitrates? - ANSTake off at night
Long-acting Nitrates are contraindicated to who? - ANSPeople with GLAUCOMA **
Patient walks into emergency room with chest pain - ANSM-Morphine
O-Oxygen
N-Nitroglycerin
A-Asprin
(Improves supply and demand)