PHARM NR566 Final Exam Study Guide 100% Verified

National STD curriculum completed in Week 5 of the course. STI/STD First line drug, dose, route, frequency Chlamydia (Among Adolescents and Adults) Azithromycin, 1 g PO once or Doxycycline, 100 mg PO 2 times/day × 7 days Uncomplicated gonococcal urethritis Ceftriaxone, 250 mg IM once, plus azithromycin, 1 g PO once Bacterial Vaginosis Metronidazole, 500 mg PO 2 times/day × 7 days or Metronidazole gel (0.75%), 1 full applicator (5 g) intravaginally once/day × 5 days or Clindamycin cream (2%), 1 full applicator (5 g) intravaginally at bedtime × 7 days Herpes Simplex Virus (First Clinical Episode) Acyclovir, 400 mg PO 3 times/day × 7–10 days (or longer) or Acyclovir, 200 mg PO 5 times/day × 7–10 days (or longer) or Famciclovir, 250 mg PO 3 times/day × 7–10 days (or longer) or Valacyclovir, 1 g PO 2 times/day × 7–10 days (or longer) Pelvic Inflammatory Disease (PID) (IM or Oral Regimens) Doxycycline (100 mg PO 2 times/day × 14 days), plus either cefoxitin (2 g IM once, boosted with probenecid 1 g PO once) or ceftriaxone (250 mg IM once), with or without metronidazole (500 mg PO 2 times/day × 14 days) Syphilis (Primary and Secondary) Benzathine penicillin G, 2.4 million units IM once  Doxazosin o Side Effects orthostatic hypotension, reflex tachycardia, and nasal congestion  Dutasteride o Patient teaching and response to delayed onset of therapeutic effect extremely long half-life (about 5 weeks); therefore it takes months to clear the NR566 Final Study Guide drug after dosing has stopped. Although many capsules can be opened and sprinkled on food, this is not the case with dutasteride. The capsule contents can be irritating to the oropharyngeal mucosa; therefore the capsule must be swallowed whole with a full glass of water.  Terazosin o How to know it’s working relaxes smooth muscle in the bladder neck (trigone and sphincter), prostate capsule, and prostatic urethra, thereby decreasing dynamic obstruction of the urethra. Symptomatic improvement and increased urinary flow develop rapidly.  Various routes of administration of estrogen therapy and when each would be used Intravaginal: are used only for local effects, prim