ABCP Review - Basic Science: Pharmacology QUESTIONS WITH 100% CORRECT ANSWERS 2023

Differentiate pharmacokinetics from pharmacodynamics. - ANSWER Pharmacodynamics is the study of what the drug does to the body - Governs the concentration-effect part of the interaction Pharmacokinetics is what the body does to the drug - Governs the dosage-concentration part of the interaction What factors influence the extent of pharmacokinetic absorption? - ANSWER Strongly influenced by chemical solubility of the drug compound Route of administration Physiochemical properties of the drug Surface area available for absorption What happens with pharmacokinetic distribution? - ANSWER Occurs after absorption into blood stream Agents may be modified during distribution - Biotransformed or inactivated - Excreted without chemical change - Distributed to non-target areas - Bind to plasma proteins