RVT ARDMS exam review Study Guide 2023.

3 causes of venous thrombosis also called, Virchow's Triad - Venous stasis, trauma/endothelial damage, hypercoagulability Venous stasis - Slowed blood flow in veins. Caused by immobility, myocardial infarction, CHF, hypotension, COPD, obesity, pregnancy, previous DVT, extrinsic compression, SVC syndrome, paraplegia, surgery associated conditions. 2 types of Trauma/endothelial damage - Intrinsic and extrinsic Intrinsic trauma is - Damage to the vessel wall from intravenous drugs or a catheter. Increased use of PICC line results in higher incidence of upper extremity thrombus, usually developing at most proximal portion of PICC line. Extrinsic trauma is - Damage caused by an accident, which can occur at any site of the body. Hypercoagulability is associated with - Pregnancy, cancer, oral contraceptives and/or hormone replacement therapy, inherited states,e.g., factor V Leiden or protein C, protein S, or Antithrombin III deficiency Sensitivity, and How to calculate? - -Ability of a test to detect disease, how many tests are correctly called positive. - # of true positives divided by # of all positive tests by gold standard, or TP/TP+FN