NRNP 6665 Final
UPDATED ACTUAL Exam Questions and CORRECT Answers
Question 1.
Agomelatine
Correct Answer: Brand: Valdoxan
Question 2.
-Melatonin multimodal (Mel-MM)
Question 3.
-Agonist at melatonergic 1 and melatonergic 2 receptors
Question 4.
-Antagonist at 5HT2C receptors
Question 5.
-Not FDA approved: Rx for Depression, Generalized anxiety disorder
Question 6.
-Initial 25 mg/day at bedtime; after 2 weeks can increase to 50 mg/day at bedtime
Question 7.
Amitriptyline (Elavil)
Correct Answer: Tricyclic antidepressant.
Question 8.
Aripiprazole (Abilify)
Correct Answer: Treatment for depression. Atypical antipsychotic. "Dopamine
stabilizer". Dopamine receptor antagonist in high concentration and also
stimulates increase of dopamine in low concentrations. Side effects: insomnia,
akathisia.
Question 9.
Brexpiprazole (Rexulti)
Correct Answer: Treatment for depression. Atypical antipsychotic
,Question 10.
Bupropion (Wellbutrin)
Correct Answer: Antidepressant and smoking cessation aid, It can treat
depression and help people quit smoking. It can also prevent depression
caused by seasonal affective disorder (SAD).
Question 11.
Citalopram (Celexa)
Correct Answer: Antidepressant, SSRI: 20-40 mg qd.
Question 12.
Clomipramine (Anafranil)
Correct Answer: -Serotonin reuptake inhibitor (S-RI) -Tricyclic antidepressant
(TCA)
Question 13.
-Parent drug is a potent serotonin reuptake inhibitor
Question 14.
Active metabolite is a potent norepinephrine/noradrenaline reuptake inhibitor
Question 15.
-Increases serotonergic neurotransmission by blocking the serotonin reuptake pump
(transporter), -Desensitization of serotonin receptors, especially serotonin 1A receptors
Question 16.
-Increases noradrenergic neurotransmission by blocking the norepinephrine reuptake
pump (transporter), -Desensitization of beta adrenergic receptors
Question 17.
-Dopamine is inactivated by norepinephrine reuptake in the frontal cortex
Question 18.
-Lacks dopamine transporters
Question 19.
-Increases dopamine neurotransmission in this part of the brain
,Question 20.
**FDA Approved for Pediatrics in tx Obsessive-compulsive disorder (OCD) (ages 10 and
older)
Question 21.
*Off-Label for Pediatric Use: Depression, Severe and treatment-resistant, depression,
Cataplexy syndrome, Anxiety, Insomnia,
Question 22.
Neuropathic pain/chronic pain
Question 23.
-Full therapeutic benefits may take 2-8 weeks
Question 24.
-Dosing: in Peds/Adolescents/Adults:
Question 25.
100-250mg/day
Question 26.
Cyamemazine (Tercian)
Correct Answer: Treatment for depression.
Question 27.
-Known as cyamepromazine
Question 28.
-Typical antipsychotic drug of the phenothiazine class.
Question 29.
-Treatment for schizophrenia
Question 30.
and psychosis-associated
Question 31.
anxiety
, Question 32.
-Behaves like an atypical antipsychotic, due to its
Question 33.
potent anxiolytic effects (5-HT2C) and lack of extrapyramidal side effects (5- HT2A).
Question 34.
-Conventional antipsychotic (neuroleptic, phenothiazine, dopamine 2 antagonist,
serotonin dopamine antagonist)
Question 35.
-Commonly Prescribed for (not FDA approved):
Question 36.
-Schizophrenia
Question 37.
-Anxiety associated with psychosis (short-term)
Question 38.
-Anxiety associated with nonpsychotic disorders, including mood disorders and
personality disorders (short-term)
Question 39.
-Severe depression
Question 40.
-Bipolar disorder
Question 41.
-Other psychotic disorders
Question 42.
-Acute agitation/aggression (injection)
Question 43.
-Benzodiazepine withdrawal
UPDATED ACTUAL Exam Questions and CORRECT Answers
Question 1.
Agomelatine
Correct Answer: Brand: Valdoxan
Question 2.
-Melatonin multimodal (Mel-MM)
Question 3.
-Agonist at melatonergic 1 and melatonergic 2 receptors
Question 4.
-Antagonist at 5HT2C receptors
Question 5.
-Not FDA approved: Rx for Depression, Generalized anxiety disorder
Question 6.
-Initial 25 mg/day at bedtime; after 2 weeks can increase to 50 mg/day at bedtime
Question 7.
Amitriptyline (Elavil)
Correct Answer: Tricyclic antidepressant.
Question 8.
Aripiprazole (Abilify)
Correct Answer: Treatment for depression. Atypical antipsychotic. "Dopamine
stabilizer". Dopamine receptor antagonist in high concentration and also
stimulates increase of dopamine in low concentrations. Side effects: insomnia,
akathisia.
Question 9.
Brexpiprazole (Rexulti)
Correct Answer: Treatment for depression. Atypical antipsychotic
,Question 10.
Bupropion (Wellbutrin)
Correct Answer: Antidepressant and smoking cessation aid, It can treat
depression and help people quit smoking. It can also prevent depression
caused by seasonal affective disorder (SAD).
Question 11.
Citalopram (Celexa)
Correct Answer: Antidepressant, SSRI: 20-40 mg qd.
Question 12.
Clomipramine (Anafranil)
Correct Answer: -Serotonin reuptake inhibitor (S-RI) -Tricyclic antidepressant
(TCA)
Question 13.
-Parent drug is a potent serotonin reuptake inhibitor
Question 14.
Active metabolite is a potent norepinephrine/noradrenaline reuptake inhibitor
Question 15.
-Increases serotonergic neurotransmission by blocking the serotonin reuptake pump
(transporter), -Desensitization of serotonin receptors, especially serotonin 1A receptors
Question 16.
-Increases noradrenergic neurotransmission by blocking the norepinephrine reuptake
pump (transporter), -Desensitization of beta adrenergic receptors
Question 17.
-Dopamine is inactivated by norepinephrine reuptake in the frontal cortex
Question 18.
-Lacks dopamine transporters
Question 19.
-Increases dopamine neurotransmission in this part of the brain
,Question 20.
**FDA Approved for Pediatrics in tx Obsessive-compulsive disorder (OCD) (ages 10 and
older)
Question 21.
*Off-Label for Pediatric Use: Depression, Severe and treatment-resistant, depression,
Cataplexy syndrome, Anxiety, Insomnia,
Question 22.
Neuropathic pain/chronic pain
Question 23.
-Full therapeutic benefits may take 2-8 weeks
Question 24.
-Dosing: in Peds/Adolescents/Adults:
Question 25.
100-250mg/day
Question 26.
Cyamemazine (Tercian)
Correct Answer: Treatment for depression.
Question 27.
-Known as cyamepromazine
Question 28.
-Typical antipsychotic drug of the phenothiazine class.
Question 29.
-Treatment for schizophrenia
Question 30.
and psychosis-associated
Question 31.
anxiety
, Question 32.
-Behaves like an atypical antipsychotic, due to its
Question 33.
potent anxiolytic effects (5-HT2C) and lack of extrapyramidal side effects (5- HT2A).
Question 34.
-Conventional antipsychotic (neuroleptic, phenothiazine, dopamine 2 antagonist,
serotonin dopamine antagonist)
Question 35.
-Commonly Prescribed for (not FDA approved):
Question 36.
-Schizophrenia
Question 37.
-Anxiety associated with psychosis (short-term)
Question 38.
-Anxiety associated with nonpsychotic disorders, including mood disorders and
personality disorders (short-term)
Question 39.
-Severe depression
Question 40.
-Bipolar disorder
Question 41.
-Other psychotic disorders
Question 42.
-Acute agitation/aggression (injection)
Question 43.
-Benzodiazepine withdrawal