Physiology: Growth Hormone With Q&A 2026/2027 (100% Verified)

Physiology: Growth Hormone With Q&A

2026/2027 (100% Verified)



1. Which five factors stimulate growth hormone (GH)
secretion?

A. Hyperglycemia, high-fat intake, rest, mild exercise, and
dehydration
B. Hypoglycemia, protein deficiency, exercise, trauma, and
sleep
C. Hyperglycemia, protein excess, fasting, sleep, and fever
D. Low protein intake, hypercalcemia, rest, trauma, and
wakefulness

CORRECT ANSWER: B. Hypoglycemia, protein deficiency,
exercise, trauma, and sleep

,Explanation: Growth hormone secretion increases in response
to several physiologic stresses and metabolic conditions.
Important stimulators include hypoglycemia, protein deficiency,
exercise, physical trauma, and sleep, particularly deep sleep.
GH has important metabolic effects, including supporting the
restoration of blood glucose during hypoglycemic conditions.




2. Approximately how much growth hormone is protein-
bound in the circulation?

A. 10%
B. 25%
C. 50%
D. 90%

CORRECT ANSWER: C. 50%

Explanation: Approximately 50% of circulating growth
hormone is protein-bound. Binding to carrier proteins affects

, the hormone's distribution and clearance and contributes to
regulation of its circulating half-life.




3. What protein does growth hormone bind to in plasma?

A. Albumin
B. Thyroxine-binding globulin
C. Growth hormone-binding protein (GHBP)
D. Cortisol-binding globulin

CORRECT ANSWER: C. Growth hormone-binding protein
(GHBP)

Explanation: Growth hormone binds to growth hormone-
binding protein (GHBP) in the circulation. GHBP is derived
from the extracellular portion of the growth hormone receptor
and serves as an important circulating carrier for GH.