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NSG 3100 EXAM 4 | QUESTIONS AND ANSWERS | 2026 UPDATE | 100% CORRECT - GALEN.

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NSG 3100 Exam 4 – 50 New Questions and Answers | 2026 Update | Galen Nursing Study Guide is a focused exam-preparation resource designed for NSG 3100 students preparing for Exam 4. This study guide provides 50 newly written practice questions with answers and detailed rationales to support active learning, knowledge reinforcement, and nursing exam preparation. The resource is designed around core nursing concepts and clinical-judgment skills relevant to comprehensive exam review. Questions encourage students to apply assessment findings, prioritize patient needs, recognize safety concerns, select appropriate nursing interventions, evaluate outcomes, and use evidence-based nursing principles in realistic clinical situations.

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NSG 3100 EXAM 4 | 50 NEW

QUESTIONS AND ANSWERS |

2026 UPDATE | 100% CORRECT -

GALEN.
with correct options, detailed rationales, and alignment to
Galen BSN outcomes and NCLEX testing blueprint.


NCLEX-Style Exam Questions with Rationales for NSG 3100 -
Unit #4: Asepsis (Galen College of Nursing)




1. A nurse is caring for a client with a wound infected with
MRSA. Which PPE should the nurse use when providing
direct care?

A. Surgical mask only
B. Gloves and gown

,C. N95 respirator and gown
D. Face shield only

Correct Answer: B. Gloves and gown

Rationale: MRSA in a wound requires contact precautions.
Gloves and a gown protect the nurse from direct contact with the
infected wound and contaminated surfaces. An N95 respirator is
not routinely required unless another indication for airborne
precautions exists.




2. The nurse is preparing to enter the room of a client with
suspected active pulmonary tuberculosis. Which PPE is
required?

A. Surgical mask
B. N95 respirator
C. Gown and gloves only
D. Face shield only

Correct Answer: B. N95 respirator

Rationale: Tuberculosis is transmitted through airborne particles.
The nurse should use an appropriate fit-tested N95 respirator or

,equivalent respiratory protection and follow airborne isolation
procedures.




3. Which situation requires the nurse to wash the hands with
soap and water rather than relying only on alcohol-based hand
rub?

A. After measuring blood pressure
B. Before administering an oral medication
C. After caring for a client with C. difficile
D. After touching intact skin

Correct Answer: C. After caring for a client with C. difficile

Rationale: C. difficile produces spores that are not reliably
eliminated by alcohol-based hand rub. Soap and water provide
mechanical removal of the spores and are required after caring for
a client with C. difficile.




4. A nurse sustains a needlestick injury while administering an
injection. What should the nurse do first?

, A. Complete an incident report
B. Notify the charge nurse
C. Wash the area with soap and water
D. Obtain the client's medical history

Correct Answer: C. Wash the area with soap and water

Rationale: The immediate priority following a needlestick is
cleansing the exposed area with soap and water. After cleansing,
the nurse should promptly report the exposure and follow the
facility's occupational-exposure protocol.




5. Which client requires airborne precautions?

A. Client with influenza
B. Client with MRSA wound infection
C. Client with pulmonary tuberculosis
D. Client with C. difficile diarrhea

Correct Answer: C. Client with pulmonary tuberculosis

Rationale: Pulmonary tuberculosis is transmitted through airborne
particles and requires airborne precautions, including appropriate
respiratory protection and an airborne infection isolation room.

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