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ALL COMSAE ACTUAL EXAM QUESTIONS AND CORRECT ANSWERS LATEST MOST QUESTIONS COVERED GRADED A+

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Download the COMSAE Comprehensive Study Guide & Practice Questions (Latest 2026/2027 Edition), a comprehensive exam preparation resource designed to strengthen foundational medical knowledge, clinical reasoning, and osteopathic medical concepts. This study guide features board-style practice questions with detailed answer explanations covering internal medicine, family medicine, pediatrics, obstetrics and gynecology, surgery, psychiatry, emergency medicine, preventive medicine, pathology, pharmacology, microbiology, physiology, anatomy, biochemistry, behavioral science, ethics, osteopathic principles and practice (OPP/OMM), diagnostic interpretation, patient management, evidence-based medicine, and clinical decision-making. Ideal for osteopathic medical students preparing for COMSAE Phase 1, Phase 2, and Phase 3, COMLEX-USA®, medical school comprehensive assessments, and board examination review.

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ALL COMSAE ACTUAL EXAM

QUESTIONS AND CORRECT

ANSWERS LATEST MOST

QUESTIONS COVERED

GRADED A+

Giardia lamblia - CORRECT ANSWER -tinidazole or nitazoxanide (alt:
metronidazole)




Entamoeba histolytica - CORRECT ANSWER -metronidazole or
tinidazole, then paromomycin or iodoquinol




Ascaris lumbricoides - CORRECT ANSWER -albendazole or
mebendazole

,Necator americanus - CORRECT ANSWER -albendazole (alt:
mebendazole)




Trichinella spiralis - CORRECT ANSWER -albendazole + prednisone




Enterobius vermicularis - CORRECT ANSWER -mebendazole




Shistosoma spp. - CORRECT ANSWER -praziquantel




Diphyllobothrium latum - CORRECT ANSWER -praziquantel (alt:
niclosamide)




Yersinia Pestis - CORRECT ANSWER -Streptomycin (alt: gentamicin




Adenovirus (severe infection) - CORRECT ANSWER -cidofovir +
probenecid

,Influenza A (seasonal), Influenza B, adn avian flu (H5N1) - CORRECT
ANSWER -zanamivir or oseltamivir




Measles - CORRECT ANSWER --Children: vitamin A

-Adults: ribavirin




Smallpox - CORRECT ANSWER -smallpox vaccine within 4 days of
exposure + cidofovir + probenecid Osteomyelitis (<4 months old) -
CORRECT ANSWER -nafcillin or oxacillin + ceftazidime or cefepime




Osteomyelitis (4 months - adult) - CORRECT ANSWER -nafcillin or
oxacillin




Herpes Encephalitis - CORRECT ANSWER --acyclovir

-if HSV (+): acyclovir

-If not HSV (+): DOC for specific etiologic agent




Encephalitis due to Rickettsia, Anaplasma, Ehrlichia, Bartonella, or
Mycoplasma - CORRECT ANSWER Doxycycline

, Encephalitis due to Borrelia burgdorferi - CORRECT ANSWER -
Ceftriaxone




Meningitis in neonate, child, or adult - CORRECT ANSWER -ampicillin
+ cefotaxime + gentamicin + ceftriaxone or cefotaxime +
dexamethasone + vacomycin




Meningitis in alcoholics, people >50, people with severe comorbid
diseases, or anyone who is immunocompromised - CORRECT
ANSWER -ceftriaxone or cefotaxime + dexamethasone + vacomycin +
ampcillin




Meningitis prophylaxis if hemophilus influenzae - CORRECT ANSWER
-rifampin




Meningitis prophylaxis if neisseria meningitidis - CORRECT ANSWER -
rifampin or ceftriaxone or ciprofloxacin

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