COMSAE Phase 2 – BSA 110 Practice Exam
(2026 Edition): Comprehensive Multiple-
Choice Questions, Answers, and Detailed
Rationales
1. A 65-year-old man presents with exertional chest pain
relieved by rest. Most likely diagnosis?
A. GERD
B. Stable angina
C. Pericarditis
D. Pulmonary embolism
Answer: B. Stable angina
Exertional, predictable chest pain relieved by rest is classic for
stable angina due to fixed coronary atherosclerosis.
2. Most common cause of community-acquired pneumonia
in adults?
A. Klebsiella pneumoniae
B. Streptococcus pneumoniae
C. Pseudomonas aeruginosa
D. Mycoplasma pneumoniae
Answer: B. Streptococcus pneumoniae
It remains the most common bacterial cause of CAP in adults.
,3. First-line treatment for acute anaphylaxis?
A. Diphenhydramine
B. Epinephrine
C. Prednisone
D. Albuterol
**Answer: B. Epinephrine
IM epinephrine is the first and most critical treatment,
reversing airway edema and hypotension.
4. Most likely diagnosis in a smoker with hematuria and
painless bladder mass?
A. Renal cell carcinoma
B. Bladder cancer
C. UTI
D. Kidney stone
**Answer: B. Bladder cancer
Painless hematuria in a smoker strongly suggests urothelial
carcinoma.
5. Which condition shows “ground glass” appearance on
chest CT?
A. COPD
B. Pulmonary edema
C. ARDS
D. Asthma
**Answer: C. ARDS
Diffuse alveolar damage leads to ground-glass opacities.
,6. Most common cause of iron deficiency anemia in adult
men?
A. Menstruation
B. GI blood loss
C. Diet deficiency
D. Hemolysis
**Answer: B. GI blood loss
In adult men, iron deficiency anemia is assumed to be from GI
bleeding until proven otherwise.
7. First-line treatment for type 2 diabetes?
A. Insulin
B. Metformin
C. Sulfonylureas
D. GLP-1 agonist
**Answer: B. Metformin
Improves insulin sensitivity and decreases hepatic
gluconeogenesis.
8. Most likely cause of acute pancreatitis in US?
A. Alcohol
B. Gallstones
C. Trauma
D. Steroids
**Answer: B. Gallstones
, Gallstones and alcohol are most common; gallstones lead in
many populations.
9. ECG finding in hyperkalemia?
A. ST elevation
B. Peaked T waves
C. U waves
D. Prolonged QT
**Answer: B. Peaked T waves
Early sign of hyperkalemia is tall, peaked T waves.
10. Most common cause of meningitis in neonates?
A. E. coli
B. Listeria monocytogenes
C. Streptococcus pneumoniae
D. Neisseria meningitidis
**Answer: A. E. coli
Along with Group B strep, E. coli is a leading neonatal cause.
11. Treatment for peptic ulcer disease with H. pylori?
A. PPI only
B. Triple therapy
C. H2 blocker
D. Antacids only
**Answer: B. Triple therapy
(2026 Edition): Comprehensive Multiple-
Choice Questions, Answers, and Detailed
Rationales
1. A 65-year-old man presents with exertional chest pain
relieved by rest. Most likely diagnosis?
A. GERD
B. Stable angina
C. Pericarditis
D. Pulmonary embolism
Answer: B. Stable angina
Exertional, predictable chest pain relieved by rest is classic for
stable angina due to fixed coronary atherosclerosis.
2. Most common cause of community-acquired pneumonia
in adults?
A. Klebsiella pneumoniae
B. Streptococcus pneumoniae
C. Pseudomonas aeruginosa
D. Mycoplasma pneumoniae
Answer: B. Streptococcus pneumoniae
It remains the most common bacterial cause of CAP in adults.
,3. First-line treatment for acute anaphylaxis?
A. Diphenhydramine
B. Epinephrine
C. Prednisone
D. Albuterol
**Answer: B. Epinephrine
IM epinephrine is the first and most critical treatment,
reversing airway edema and hypotension.
4. Most likely diagnosis in a smoker with hematuria and
painless bladder mass?
A. Renal cell carcinoma
B. Bladder cancer
C. UTI
D. Kidney stone
**Answer: B. Bladder cancer
Painless hematuria in a smoker strongly suggests urothelial
carcinoma.
5. Which condition shows “ground glass” appearance on
chest CT?
A. COPD
B. Pulmonary edema
C. ARDS
D. Asthma
**Answer: C. ARDS
Diffuse alveolar damage leads to ground-glass opacities.
,6. Most common cause of iron deficiency anemia in adult
men?
A. Menstruation
B. GI blood loss
C. Diet deficiency
D. Hemolysis
**Answer: B. GI blood loss
In adult men, iron deficiency anemia is assumed to be from GI
bleeding until proven otherwise.
7. First-line treatment for type 2 diabetes?
A. Insulin
B. Metformin
C. Sulfonylureas
D. GLP-1 agonist
**Answer: B. Metformin
Improves insulin sensitivity and decreases hepatic
gluconeogenesis.
8. Most likely cause of acute pancreatitis in US?
A. Alcohol
B. Gallstones
C. Trauma
D. Steroids
**Answer: B. Gallstones
, Gallstones and alcohol are most common; gallstones lead in
many populations.
9. ECG finding in hyperkalemia?
A. ST elevation
B. Peaked T waves
C. U waves
D. Prolonged QT
**Answer: B. Peaked T waves
Early sign of hyperkalemia is tall, peaked T waves.
10. Most common cause of meningitis in neonates?
A. E. coli
B. Listeria monocytogenes
C. Streptococcus pneumoniae
D. Neisseria meningitidis
**Answer: A. E. coli
Along with Group B strep, E. coli is a leading neonatal cause.
11. Treatment for peptic ulcer disease with H. pylori?
A. PPI only
B. Triple therapy
C. H2 blocker
D. Antacids only
**Answer: B. Triple therapy
