Advance Pharmacy NR565 MIDTERM(2
] ] ]
026) Predictor Questions with Correct V
] ] ] ] ]
erified Answers!! ]
·· ]Which ]schedule ]drugs ]can ]APRNs ]prescribe? ]- ]correct ]answer: ]Schedule ]II-V
· ]Who ]determines ]and ]regulates ]prescriptive ]authority? ]- ]correct ]answer: ]Nurse ]practitioner ]sco
pe ]of ]practice ]is ]determined ]by ]state ]practice ]and ]licensure ]laws.
· ]How ]does ]limited ]prescriptive ]authority ]impact ]patients ]within ]the ]healthcare ]system? ]- ]correc
t ]answer: ]limited ]authority ]creates ]problems ]for ]the ]patient. ]The ]patient ]is ]not ]able ]to ]get ]the ]ca
re ]they ]need
· ]What ]are ]the ]key ]responsibilities ]of ]prescribing? ]- ]correct ]answer: ]1. ]Be ]prudent ]and ]deliberate
]in ]your ]decision-making ]process
2. ]Have ]a ]documented ]provider-
patient ]relationship ]with ]the ]person ]for ]whom ]you ]are ]prescribing
3. ]Do ]not ]prescribe ]medications ]for ]family ]or ]friends ]or ]for ]yourself
4. ]Document ]a ]thorough ]history ]and ]physical ]examination ]in ]your ]records
5.Include ]any ]discussions ]you ]have ]with ]the ]patient ]regarding ]risk ]factors, ]side ]effects, ]or ]therap
y ]options
6. ]Have ]a ]documented ]plan ]regarding ]drug ]monitoring ]or ]titration, ]if ]applicable
· ]What ]should ]be ]used ]to ]make ]prescribing ]decisions? ]- ]correct ]answer: ]
Pharmakinetiscs ]and ]Pharmodynamics ]of ]older ]adults ]- ]correct ]answer: ]drug ]accumulation ]seco
ndary ]to ]reduced ]renal ]function
,polypharmacy ](the ]use ]of ]five ]or ]more ]medications ]daily)
greater ]severity ]of ]illness
presence ]of ]comorbidities
use ]of ]drugs ]that ]have ]a ]low ]therapeutic ]index ](e.g., ]digoxin)
increased ]individual ]variation ]secondary ]to ]altered ]pharmacokinetics
inadequate ]supervision ]of ]long-term ]therapy
poor ]patient ]adherence
· ]Beer's ]Criteria ]- ]correct ]answer: ]•potentially ]Inappropriate ]Medication ]
(PIM) ]use ]in ]older ]adults
•PIM ]use ]in ]older ]adults ]due ]to ]medication-disease ]or ]medication-
syndrome ]interactions ]that ]may ]exacerbate ]the ]disease ]or ]syndrome
•medications ]to ]be ]used ]cautiously ]in ]older ]adults
•clinically ]significant ]drug ]interactions ]that ]should ]be ]avoided ]in ]older ]adults
•medications ]to ]be ]avoided ]or ]dosage ]decreased ]in ]the ]presence ]of ]impaired ]kidney ]function ]in ]
older ]adults ](American ]Geriatric ]Society ]Beers ]Criteria ]Update ]Expert ]Panel, ]2019)
CYP450 ]- ]correct ]answer: ]Many ]medications ]are ]metabolized ]through ]the ]liver ]enzyme ]system ]c
alled ]cytochrome ]P450 ]
(CYP450). ]Metabolization ]can ]be ]inhibited ]or ]induced ]by ]drugs ]and ]once ]this ]happens ]drug-
drug ]interactions ]can ]occur.
VISA ]credit ]card ]dept ]Inhibits ]Spending ]on ]CK ]and ]GQ ]- ]correct ]answer: ]Valproate
I-soniazid
S-ulfamids
A-miodarone
C-hloramphenical
, Ketoconazole
G-rapefruit ]Juice ]
Q-uinidine
CYP450 ]Inhibitors ]- ]correct ]answer: ]- ]Decreases ]the ]CYP450 ]which ]keeps ]the ]medication ]in ]your ]
body ]longer ]which ]can ]cause ]toxicity
CYP450 ]INDUCERS ]- ]correct ]answer: ]Increase ]CYP450 ]to ]work ]faster ]causes ]
Drugs ]to ]leave ]your ]body ]faster.
Inducers ]for ]PY450 ]Chronic ]Alcholics ]Steal ]Phen ]Phen ]and ]Never ]Refuse ]Greasy ]Carbs ]- ]correct ]a
nswer: ]Chronic ]Alcoholics ]
St. ]Johns ]Wort ]
Phenytoin ]
Phenobarbital ]
Nevirapine
Refiampin ]
]
Griseofalvin ]
Carbamazepine
· ]What ]happens ]when ]someone ]has ]a ]poor ]metabolism ]phenotype? ]- ]correct ]answer: ]Metaboliz
es ]to ]slow ]or ]to ]fast.
How ]is ]absorption ]of ]intramuscular ]medication ]different ]in ]neonates? ]- ]correct ]answer: ]•Slow ]a
nd ]erratic ]due ]to ]low ]blood ]flow ]in ]muscles ]first ]few ]days ]of ]life
] ] ]
026) Predictor Questions with Correct V
] ] ] ] ]
erified Answers!! ]
·· ]Which ]schedule ]drugs ]can ]APRNs ]prescribe? ]- ]correct ]answer: ]Schedule ]II-V
· ]Who ]determines ]and ]regulates ]prescriptive ]authority? ]- ]correct ]answer: ]Nurse ]practitioner ]sco
pe ]of ]practice ]is ]determined ]by ]state ]practice ]and ]licensure ]laws.
· ]How ]does ]limited ]prescriptive ]authority ]impact ]patients ]within ]the ]healthcare ]system? ]- ]correc
t ]answer: ]limited ]authority ]creates ]problems ]for ]the ]patient. ]The ]patient ]is ]not ]able ]to ]get ]the ]ca
re ]they ]need
· ]What ]are ]the ]key ]responsibilities ]of ]prescribing? ]- ]correct ]answer: ]1. ]Be ]prudent ]and ]deliberate
]in ]your ]decision-making ]process
2. ]Have ]a ]documented ]provider-
patient ]relationship ]with ]the ]person ]for ]whom ]you ]are ]prescribing
3. ]Do ]not ]prescribe ]medications ]for ]family ]or ]friends ]or ]for ]yourself
4. ]Document ]a ]thorough ]history ]and ]physical ]examination ]in ]your ]records
5.Include ]any ]discussions ]you ]have ]with ]the ]patient ]regarding ]risk ]factors, ]side ]effects, ]or ]therap
y ]options
6. ]Have ]a ]documented ]plan ]regarding ]drug ]monitoring ]or ]titration, ]if ]applicable
· ]What ]should ]be ]used ]to ]make ]prescribing ]decisions? ]- ]correct ]answer: ]
Pharmakinetiscs ]and ]Pharmodynamics ]of ]older ]adults ]- ]correct ]answer: ]drug ]accumulation ]seco
ndary ]to ]reduced ]renal ]function
,polypharmacy ](the ]use ]of ]five ]or ]more ]medications ]daily)
greater ]severity ]of ]illness
presence ]of ]comorbidities
use ]of ]drugs ]that ]have ]a ]low ]therapeutic ]index ](e.g., ]digoxin)
increased ]individual ]variation ]secondary ]to ]altered ]pharmacokinetics
inadequate ]supervision ]of ]long-term ]therapy
poor ]patient ]adherence
· ]Beer's ]Criteria ]- ]correct ]answer: ]•potentially ]Inappropriate ]Medication ]
(PIM) ]use ]in ]older ]adults
•PIM ]use ]in ]older ]adults ]due ]to ]medication-disease ]or ]medication-
syndrome ]interactions ]that ]may ]exacerbate ]the ]disease ]or ]syndrome
•medications ]to ]be ]used ]cautiously ]in ]older ]adults
•clinically ]significant ]drug ]interactions ]that ]should ]be ]avoided ]in ]older ]adults
•medications ]to ]be ]avoided ]or ]dosage ]decreased ]in ]the ]presence ]of ]impaired ]kidney ]function ]in ]
older ]adults ](American ]Geriatric ]Society ]Beers ]Criteria ]Update ]Expert ]Panel, ]2019)
CYP450 ]- ]correct ]answer: ]Many ]medications ]are ]metabolized ]through ]the ]liver ]enzyme ]system ]c
alled ]cytochrome ]P450 ]
(CYP450). ]Metabolization ]can ]be ]inhibited ]or ]induced ]by ]drugs ]and ]once ]this ]happens ]drug-
drug ]interactions ]can ]occur.
VISA ]credit ]card ]dept ]Inhibits ]Spending ]on ]CK ]and ]GQ ]- ]correct ]answer: ]Valproate
I-soniazid
S-ulfamids
A-miodarone
C-hloramphenical
, Ketoconazole
G-rapefruit ]Juice ]
Q-uinidine
CYP450 ]Inhibitors ]- ]correct ]answer: ]- ]Decreases ]the ]CYP450 ]which ]keeps ]the ]medication ]in ]your ]
body ]longer ]which ]can ]cause ]toxicity
CYP450 ]INDUCERS ]- ]correct ]answer: ]Increase ]CYP450 ]to ]work ]faster ]causes ]
Drugs ]to ]leave ]your ]body ]faster.
Inducers ]for ]PY450 ]Chronic ]Alcholics ]Steal ]Phen ]Phen ]and ]Never ]Refuse ]Greasy ]Carbs ]- ]correct ]a
nswer: ]Chronic ]Alcoholics ]
St. ]Johns ]Wort ]
Phenytoin ]
Phenobarbital ]
Nevirapine
Refiampin ]
]
Griseofalvin ]
Carbamazepine
· ]What ]happens ]when ]someone ]has ]a ]poor ]metabolism ]phenotype? ]- ]correct ]answer: ]Metaboliz
es ]to ]slow ]or ]to ]fast.
How ]is ]absorption ]of ]intramuscular ]medication ]different ]in ]neonates? ]- ]correct ]answer: ]•Slow ]a
nd ]erratic ]due ]to ]low ]blood ]flow ]in ]muscles ]first ]few ]days ]of ]life