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HU-NU 661 (AGPCNP I) Latest Final Exam 2026 (Qns & Ans)

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AGPCNP I is where your journey as an advanced practice nurse truly begins to take shape, and the final exam reflects that weight. This 2026 exam prep file covers the breadth of content you have been working through all semester, including health promotion across the adult lifespan, chronic disease screening, physical assessment findings, and differential diagnosis fundamentals. Each question in this file mirrors the clinical vignette style commonly used in NP-level exams, so you are not just preparing for this final but also building a foundation for your board exam. The answers are written with enough depth to explain the clinical rationale, not just hand you a letter choice. If you have been juggling clinical rotations and coursework and feel stretched thin heading into finals week, this is the focused, high-yield review that will make the most of your remaining study time.

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HERZING UNIVERSITY
Course Code: NU 661
Instructor:
Date: 2026

FINAL EXAM – ADULT GERONTOLOGY PRIMARY CARE
NURSE PRACTITIONER I




A 62-year-old patient with type 2 diabetes presents for routine screening. The
latest A1C is 7.8%. According to current ADA guidelines, the next best step
in management is:
A) Intensify lifestyle modifications and consider adding a second oral agent
B) Maintain current therapy since A1C < 8% is acceptable in older adults
C) Switch immediately to insulin therapy
D) Discontinue all oral hypoglycemics

Answer: A) Intensify lifestyle modifications and consider adding a second oral
agent
Rationale: ADA guidelines recommend intensifying treatment if A1C is above
individualized targets, often <7.5-8.0% in older adults, balancing benefits and
risks. Insulin is not first line without previous trials of oral therapy
optimization.

A 45-year-old patient presents with newly diagnosed hypertension. Which of
the following should be included as first-line pharmacotherapy according to
JNC-8 guidelines?
A) Beta-blockers alone
B) Thiazide diuretics or ACE inhibitors
C) Alpha-blockers
D) Calcium channel blockers only in black patients
1

,Answer: B) Thiazide diuretics or ACE inhibitors
Rationale: JNC-8 recommends thiazides, ACE inhibitors, ARBs, or CCBs as
first-line. Beta-blockers and alpha-blockers are not first-line unless specific
indications exist.

True or False: The USPSTF recommends annual colorectal cancer
screening in adults aged 45-75 years.
Answer: False
Rationale: USPSTF recommends colorectal cancer screening beginning at
age 45 but not necessarily annually. The preferred intervals vary by
screening modality (e.g., colonoscopy every 10 years).

Fill in the blank: According to the GOLD guidelines, the primary
pharmacological treatment for COPD patients with frequent exacerbations
and a high eosinophil count is ___________.
Answer: inhaled corticosteroids (ICS) combined with long-acting
bronchodilators
Rationale: GOLD promotes ICS + LABA or LAMA in patients at risk of
exacerbations and eosinophilia to reduce inflammation and exacerbation
frequency.

A 55-year-old woman with a history of major depressive disorder is being
considered for antidepressant therapy. Which class of medications is most
commonly recommended as first-line treatment?
A) MAO inhibitors
B) Selective serotonin reuptake inhibitors (SSRIs)
C) Tricyclic antidepressants
D) Benzodiazepines

Answer: B) Selective serotonin reuptake inhibitors (SSRIs)
Rationale: SSRIs balance efficacy with tolerability and safety. MAO inhibitors
and tricyclics have more contraindications and side effects.

True or False: The initial evaluation of a patient with newly suspected heart
failure should include B-type natriuretic peptide (BNP) testing.
Answer: True
Rationale: BNP or NT-proBNP is recommended to help differentiate heart
failure from other causes of dyspnea and guide early diagnosis.

Fill in the blank: The most appropriate cancer screening test for lung cancer
in a 60-year-old heavy smoker is ___________.
Answer: low-dose computed tomography (LDCT) scan
2

, Rationale: USPSTF endorses annual LDCT for lung cancer screening in
adults aged 50-80 years with significant smoking history.

In the assessment of chronic kidney disease (CKD), an estimated glomerular
filtration rate (eGFR) less than ______ ml/min/1.73 m² indicates stage 3
CKD.
A) 45
B) 60
C) 90
D) 30

Answer: B) 60
Rationale: CKD stage 3 is defined as eGFR between 30-59 ml/min/1.73 m²,
stage 3a (45-59) and 3b (30-44).

True or False: Annual influenza vaccination is recommended for all adults,
including those over 65 years of age, as per CDC guidelines.
Answer: True
Rationale: Annual flu vaccination reduces morbidity and mortality, especially
in high-risk groups including older adults.

A 70-year-old individual with COPD complains of increasing dyspnea. Pulse
oximetry reading is 88%. The best immediate management is:
A) Start systemic corticosteroids
B) Provide supplemental oxygen to maintain saturation above 90%
C) Initiate antibiotics
D) Schedule pulmonary function tests

Answer: B) Provide supplemental oxygen to maintain saturation above 90%
Rationale: Hypoxemia requires oxygen therapy to prevent hypoxic
complications. Further evaluations follow.

Fill in the blank: The key biomarker for cardiac muscle injury in suspected
acute coronary syndrome is __________.
Answer: troponin I or T
Rationale: Troponins are highly sensitive and specific markers for myocardial
injury and are standard in ACS diagnosis.

True or False: The American Diabetes Association recommends annual
screening for diabetic retinopathy starting at diagnosis in type 1 diabetes and
within 5 years post-diagnosis for type 2 diabetes.
Answer: True
Rationale: Retinopathy develops later in type 1; type 2 diabetes often is
3

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