UNE BIOCHEMISTRY ACTUAL UPDATED QUESTIONS AND
ANSWERS GUARANTEE A+
✔✔Excessive alcohol consumption increases the ratio of NADH/NAD+. This will directly
inhibit which of the following enzymes in the TCA cycle? - ✔✔Alpha keto glutarate
dehydrogenase
✔✔When glucagon binds to receptors on mammalian liver cells, it activates Protein
Kinase A. This kinase will phosphorylate regulatory enzymes and have which of the
following impacts on metabolism? - ✔✔Activation of glycogen phosphorylase and
activation of glycogenolysis
✔✔Elevated levels of NADH produced from the oxidation of alcohol can disrupt the TCA
cycle. Which of the following best describes the interaction of NADH with isocitrate
dehydrogenase? - ✔✔NADH is an inhibitor of the enzyme
✔✔Under fasted conditions which process provides a primary oxidizable substrate for
the brain? - ✔✔Hepatic glycogenolysis
✔✔When cortisol binds to its receptor, which of the following events occur to stimulate
gluconeogesis? - ✔✔Enhanced transcription of regulatory enzymes
✔✔If unregulated, which of the following pairs of enzymes would represent a futile
cycle?
A. Phosphofructokinase 2 (PFK2) and acetylCoA carboxylase
B. Glucose-6-phosphatase and glucokinase
C. Pyruvate kinase and glucokinase
D. Pyruvate carboxylase and Phosphofructokinase 1(PFK1)
E. Citrate synthase and AcetylCoA carboxylase - ✔✔THE ANSWER IS NOT: Pyruvate
carboxylase and Phosphofructokinase 1(PFK1)
✔✔Which of the following amino acids is considered non-essential because it is
generated by the urea cycle? - ✔✔Arginine
✔✔The urea cycle takes place in which of the following sub cellular locations? - ✔✔The
cytosol and the mitochondria
✔✔Ubiquitination is a means of targeting a protein for which of the following cellular
proceses? - ✔✔Proteasomal degradation
, ✔✔The reaction of ammonia with α-ketoglutarate is catalyzed by _________ and
requires _________ as a reactant. - ✔✔Glutamate dehydrogenase, NADH or NADPH
✔✔Most enzymes involved in protein digestion require cleavage for activation. These
proteins are secreted as inactive protein forms called - ✔✔Zymogens
✔✔Which of the following enzymes is regulated by N-acetyl glutamate (NAGs)?
A. CPS II
B. ornithine transcarbamylase
C. arginosuccinate lyase
D. CPS I - ✔✔CPS I
✔✔Which of the following enzymes will be active in both the fed and fasted states?
A. Glutaminase
B. Pyruvate kinase
C. Hormone sensitive lipase
D. Glycogen synthase - ✔✔Glutaminase
✔✔Which of the following enzymes is correctly paired with its activator?
A. N-acetylglutamate synthtase; arginine
B. Carbamoyl phosphate synthetase I; ATP
C. Glutaminase; citrate
D. arginase; NADH - ✔✔N-acetylglutamate synthtase; arginine
✔✔In the case of a urea cycle deficiency, which of the following amino acids may
become essential? - ✔✔Arginine
✔✔The glucose alanine cycle is a method of transferring ammonia from the skeletal
muscle to the liver. In this process the non-toxic carrier of ammonia is which of the
following compounds? - ✔✔Alanine
ANSWERS GUARANTEE A+
✔✔Excessive alcohol consumption increases the ratio of NADH/NAD+. This will directly
inhibit which of the following enzymes in the TCA cycle? - ✔✔Alpha keto glutarate
dehydrogenase
✔✔When glucagon binds to receptors on mammalian liver cells, it activates Protein
Kinase A. This kinase will phosphorylate regulatory enzymes and have which of the
following impacts on metabolism? - ✔✔Activation of glycogen phosphorylase and
activation of glycogenolysis
✔✔Elevated levels of NADH produced from the oxidation of alcohol can disrupt the TCA
cycle. Which of the following best describes the interaction of NADH with isocitrate
dehydrogenase? - ✔✔NADH is an inhibitor of the enzyme
✔✔Under fasted conditions which process provides a primary oxidizable substrate for
the brain? - ✔✔Hepatic glycogenolysis
✔✔When cortisol binds to its receptor, which of the following events occur to stimulate
gluconeogesis? - ✔✔Enhanced transcription of regulatory enzymes
✔✔If unregulated, which of the following pairs of enzymes would represent a futile
cycle?
A. Phosphofructokinase 2 (PFK2) and acetylCoA carboxylase
B. Glucose-6-phosphatase and glucokinase
C. Pyruvate kinase and glucokinase
D. Pyruvate carboxylase and Phosphofructokinase 1(PFK1)
E. Citrate synthase and AcetylCoA carboxylase - ✔✔THE ANSWER IS NOT: Pyruvate
carboxylase and Phosphofructokinase 1(PFK1)
✔✔Which of the following amino acids is considered non-essential because it is
generated by the urea cycle? - ✔✔Arginine
✔✔The urea cycle takes place in which of the following sub cellular locations? - ✔✔The
cytosol and the mitochondria
✔✔Ubiquitination is a means of targeting a protein for which of the following cellular
proceses? - ✔✔Proteasomal degradation
, ✔✔The reaction of ammonia with α-ketoglutarate is catalyzed by _________ and
requires _________ as a reactant. - ✔✔Glutamate dehydrogenase, NADH or NADPH
✔✔Most enzymes involved in protein digestion require cleavage for activation. These
proteins are secreted as inactive protein forms called - ✔✔Zymogens
✔✔Which of the following enzymes is regulated by N-acetyl glutamate (NAGs)?
A. CPS II
B. ornithine transcarbamylase
C. arginosuccinate lyase
D. CPS I - ✔✔CPS I
✔✔Which of the following enzymes will be active in both the fed and fasted states?
A. Glutaminase
B. Pyruvate kinase
C. Hormone sensitive lipase
D. Glycogen synthase - ✔✔Glutaminase
✔✔Which of the following enzymes is correctly paired with its activator?
A. N-acetylglutamate synthtase; arginine
B. Carbamoyl phosphate synthetase I; ATP
C. Glutaminase; citrate
D. arginase; NADH - ✔✔N-acetylglutamate synthtase; arginine
✔✔In the case of a urea cycle deficiency, which of the following amino acids may
become essential? - ✔✔Arginine
✔✔The glucose alanine cycle is a method of transferring ammonia from the skeletal
muscle to the liver. In this process the non-toxic carrier of ammonia is which of the
following compounds? - ✔✔Alanine
