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Exam (elaborations)
South University Tampa Exam Questions and Answers | 
latest Update | 100% Correct. 
When was the program established? 
2009 
What is the educational goal of the program? 
to provide a primary care-oriented training program for physician assistants. 
*reca
South University Tampa Exam Questions and Answers | 
latest Update | 100% Correct. 
When was the program established? 
2009 
What is the educational goal of the program? 
to provide a primary care-oriented training program for physician assistants. 
*recall: Primary care is the day-to-day healthcare given by a health care 
provider.Typically this provider acts as the first contact and principal point of 
continuing care for patients within a healthcare system, and coordinates other 
specialist c...
Exam (elaborations)
SN1 & SN2 Reactions Questions with Complete Solutions 
|latest update 
List from 1 to 5 to worst/best leaving groups 5 being the best and 1 being the 
worst 
(5) I, Br, Cl, F (1) 
SN2 attacks from 
Backside 
What is the intermediate transition state? 
Pen
PopularSN1 & SN2 Reactions Questions with Complete Solutions 
|latest update 
List from 1 to 5 to worst/best leaving groups 5 being the best and 1 being the 
worst 
(5) I, Br, Cl, F (1) 
SN2 attacks from 
Backside 
What is the intermediate transition state? 
Pentacoordinate state 
What is the rate determining step in SN2? 
Transition state determin
Exam (elaborations)
SN1 and SN2 Nucleophilic Substitution Mechanisms in Organic 
Chemistry Questions with Complete Solutions |latest update 
What are the two types of nucleophilic substitution reactions? -SN1 and 
SN2 
In SN1 reactions, what is the rate limiting step depende
SN1 and SN2 Nucleophilic Substitution Mechanisms in Organic 
Chemistry Questions with Complete Solutions |latest update 
What are the two types of nucleophilic substitution reactions? -SN1 and 
SN2 
In SN1 reactions, what is the rate limiting step dependent on? -The 
concentration of one molecule ([R-LG]) 
In SN2 reactions, what is the rate limiting step dependent on? -The 
concentration of two molecu
Exam (elaborations)
SN1 and SN2 Organic Chemistry Mechanisms, Factors, and 
Stereochemistry Questions with Complete Solutions |latest 
update 
What does SN1 stand for? -Substitution Nucleophilic Unimolecular 
What does SN2 stand for? -Substitution Nucleophilic Bimolecular 
W
SN1 and SN2 Organic Chemistry Mechanisms, Factors, and 
Stereochemistry Questions with Complete Solutions |latest 
update 
What does SN1 stand for? -Substitution Nucleophilic Unimolecular 
What does SN2 stand for? -Substitution Nucleophilic Bimolecular 
What factors can affect the mechanism of substitution reactions? - 
Structure of the electrophile, reactivity of the nucleophile, solvent of the 
reaction, temperature. 
What happens to stereochemistry in an SN2 reaction if the starting material ...
Exam (elaborations)
SN1 and SN2 Reaction Mechanisms, Characteristics, and 
Applications in Organic Chemistry Questions with Complete 
Solutions |latest update 
Bimolecular Nucleophilic Substitution (SN2) -A reaction mechanism where 
a nucleophile attacks an electrophile simu
SN1 and SN2 Reaction Mechanisms, Characteristics, and 
Applications in Organic Chemistry Questions with Complete 
Solutions |latest update 
Bimolecular Nucleophilic Substitution (SN2) -A reaction mechanism where 
a nucleophile attacks an electrophile simultaneously as a leaving group departs, 
resulting in a single transition state. 
Unimolecular Nucleophilic Substitution (SN1) -A reaction mechanism that 
involves two steps: the formation of a carbocation intermediate followed by 
nucleophilic a...
Exam (elaborations)
SN1 and SN2 Reactions Basics Lessons 18 and 19 Questions 
with Complete Solutions |latest update 
rate of reaction depends on 
number of collisions per unit of time, sufficient energy, proper orientation 
SN2 reaction formula 
k[alkyl halide][nucleophile]
SN1 and SN2 Reactions Basics Lessons 18 and 19 Questions 
with Complete Solutions |latest update 
rate of reaction depends on 
number of collisions per unit of time, sufficient energy, proper orientation 
SN2 reaction formula 
k[alkyl halide][nucleophile] 
RDS of an SN2 reaction 
bimolecular reaction where the RDS involves both the substrate and the 
nucleophile. reaction is concerted 
describe the transition sta
Exam (elaborations)
SN1 and SN2 Reactions in Organic Chemistry Questions with 
Complete Solutions |latest update 
What does a nucleophile do in a reaction? -Replaces a leaving group. 
What is the mechanism of SN1 reactions? -Two steps: leaving group 
leaves, then nucleophile
SN1 and SN2 Reactions in Organic Chemistry Questions with 
Complete Solutions |latest update 
What does a nucleophile do in a reaction? -Replaces a leaving group. 
What is the mechanism of SN1 reactions? -Two steps: leaving group 
leaves, then nucleophile attacks carbocation. 
What is the first step in SN1 reactions? -Leaving group leaves, forming a 
carbocation. 
What occurs in the second step of SN1 reactions? -Nucleophile attacks the 
carbocation. 
What type of substrate favors SN1
Exam (elaborations)
Sn1 and Sn2 Reactions Questions with Complete Solutions 
|latest update 
What is a nucleophile? -electron rich center 
What is an electrohphile? -an electron poor center 
What is the main difference between an Sn1 and Sn2 reaction? -Sn2 is a 
one step rea
Sn1 and Sn2 Reactions Questions with Complete Solutions 
|latest update 
What is a nucleophile? -electron rich center 
What is an electrohphile? -an electron poor center 
What is the main difference between an Sn1 and Sn2 reaction? -Sn2 is a 
one step reaction, while Sn1 is a two step reaction 
What is another name for a one step reaction? -concerted reaction 
In an Sn2 reaction what does the rate depend on? -rate depends on the 
concentration of both the nucleophile and
Exam (elaborations)
Sn1 and Sn2 Reactions Questions with Complete Solutions 
|latest update 
Reaction M
Sn1 and Sn2 Reactions Questions with Complete Solutions 
|latest update 
Reaction M
Exam (elaborations)
SN1 SN2 E1 E2 Reactions Questions with Complete Solutions 
|latest update 
SN2 stands for -substitution nucleophilic bimolecular 
SN2 reaction mechanism -concerted 
inversion of configuration -when the incoming Nu attacks the leaving 
group from the back
SN1 SN2 E1 E2 Reactions Questions with Complete Solutions 
|latest update 
SN2 stands for -substitution nucleophilic bimolecular 
SN2 reaction mechanism -concerted 
inversion of configuration -when the incoming Nu attacks the leaving 
group from the back in SN2 rxn 
SN2 rxn rate -rate of the disap
Exam (elaborations)
SN2, SN1/E1, and E2 Reaction Mechanisms Organic Chemistry 
Nomenclature and Conditions Questions with Complete 
Solutions |latest update 
Methyl, Protic 
DEFINITION 
Sn2 
LOCATION
SN2, SN1/E1, and E2 Reaction Mechanisms Organic Chemistry 
Nomenclature and Conditions Questions with Complete 
Solutions |latest update 
Methyl, Protic 
DEFINITION 
Sn2 
LOCATION
Exam (elaborations)
SN1/SN2 and E1/E2 Reactions Questions with Complete 
Solutions |latest update 
An E1 and SN1 reaction are both ___molecular reactions which means _____ ? 
• unimolecular 
• their reaction rates depend solely on the concentration of the 
reactant (substrat
SN1/SN2 and E1/E2 Reactions Questions with Complete 
Solutions |latest update 
An E1 and SN1 reaction are both ___molecular reactions which means _____ ? 
• unimolecular 
• their reaction rates depend solely on the concentration of the 
reactant (substrate) 
What is the rate equation for both an E1 and SN1 reaction? 
rate = k [A] 
A = reactant (substrate) concentration 
*** Note: this is a 1st order rate order - a reaction which is dependent on a single 
substrate's concentration 
An E2 a...
Exam (elaborations)
SN1, SN2, E1, E2 Reaction Mechanisms for Organic Chemistry 
Questions with Complete Solutions |latest update 
What reaction does a primary substrate + non-basic nucleophile favor? - 
SN2 
What reactions are favored by a secondary substrate + non-basic nuc
SN1, SN2, E1, E2 Reaction Mechanisms for Organic Chemistry 
Questions with Complete Solutions |latest update 
What reaction does a primary substrate + non-basic nucleophile favor? - 
SN2 
What reactions are favored by a secondary substrate + non-basic nucleophile? - 
SN2 in polar aprotic solvent; SN1 in polar protic solvent 
What reaction does a tertiary substrate + non-basic nucleophile favor? - 
SN1 
What are examples of no
Exam (elaborations)
SN1, SN2, E1, E2, and E1cB Reaction Mechanisms in Organic 
Chemistry Questions with Complete Solutions |latest update 
SN1 -Unimolecular Substitution 
SN2 -Bimolecular Substitution 
E1 -Unimolecular Elimination 
E2 -Bimolecular Elimination 
E1cB -Conjugat
SN1, SN2, E1, E2, and E1cB Reaction Mechanisms in Organic 
Chemistry Questions with Complete Solutions |latest update 
SN1 -Unimolecular Substitution 
SN2 -Bimolecular Substitution 
E1 -Unimolecular Elimination 
E2 -Bimolecular Elimination 
E1cB -Conjugate Base Eliminatio
Exam (elaborations)
SN1, SN2, E1, E2 Characteristics and Reactions Questions with 
Complete Solutions |latest update 
What are the characteristics of an E2 mechanism? -It is bimolecular, onestep, requires a strong base, and involves anti-periplanar geometry. 
What are the ch
SN1, SN2, E1, E2 Characteristics and Reactions Questions with 
Complete Solutions |latest update 
What are the characteristics of an E2 mechanism? -It is bimolecular, onestep, requires a strong base, and involves anti-periplanar geometry. 
What are the characteristics of an E1 mechanism? -It is unimolecular, twostep (involving a carbocation intermediate), requires a weak base, and often uses 
protic solvents. 
What are the characteristics of an SN2 mechanism? -It is bimolecular, onestep, require...
Exam (elaborations)
SN1/SN2/E1/E2 Questions with Complete Solutions |latest 
update 
good leaving groups -**weak bases 
(Cl, Br, or I) 
tosylate (OTs) 
mesylate (OMs)(-OSO2CH3) 
quick check on the nature of the leaving group -** weak base 
** The other criterion a leaving gr
SN1/SN2/E1/E2 Questions with Complete Solutions |latest 
update 
good leaving groups -**weak bases 
(Cl, Br, or I) 
tosylate (OTs) 
mesylate (OMs)(-OSO2CH3) 
quick check on the nature of the leaving group -** weak base 
** The other criterion a leaving group has to meet is the nature of the carbon 
atom to which it is attached. The carbon atom must be sp3 hybridized. For our 
purposes in introductory organic chemistry, subs
Exam (elaborations)
SN1, SN2, E1, E2 Reactions Mechanisms, Clues, and Solvent 
Effects in Organic Chemistry Questions with Complete 
Solutions |latest update 
SN1 reaction -*unimolecular nucleophilic substitution reactions: 2 steps 
1. Leaving group leaves forming a positive
SN1, SN2, E1, E2 Reactions Mechanisms, Clues, and Solvent 
Effects in Organic Chemistry Questions with Complete 
Solutions |latest update 
SN1 reaction -*unimolecular nucleophilic substitution reactions: 2 steps 
1. Leaving group leaves forming a positively charged carbocation (rate limiting 
step) 
*The rate of rxn depends only on the concentration of the substrate 
rate = k [R-L] 
R-L is the alkyl group containing the leaving group 
*Anything that accelerates the formation of the carbocation i...
Exam (elaborations)
SN1 & SN2 Reactions Questions with Complete Solutions 
|latest update 
silver nitrate -silver nitrate 
2-chlorobutane -2-chlorobutane 
t-butyl bromide -t-butyl bromide 
1-bromobutane -1-bromobutane 
ethanol -ethanol 
1-chlorobutane -1-chlorobutane
SN1 & SN2 Reactions Questions with Complete Solutions 
|latest update 
silver nitrate -silver nitrate 
2-chlorobutane -2-chlorobutane 
t-butyl bromide -t-butyl bromide 
1-bromobutane -1-bromobutane 
ethanol -ethanol 
1-chlorobutane -1-chlorobutane
Exam (elaborations)
SN1 & SN2 Reactions Questions with Complete Solutions 
|latest update 
Igood nucleo
SN1 & SN2 Reactions Questions with Complete Solutions 
|latest update 
Igood nucleo
Exam (elaborations)
SN1, SN2, E1, and E2 Reactions Questions with Complete 
Solutions |latest update 
E = high priority groups on ___ -opposite sides 
Z = high priority groups on ___ -same side 
SN1 Reaction 
Substrate Preference -3 (fast) > 2 (slow) 
SN1 Reaction 
Reagen
SN1, SN2, E1, and E2 Reactions Questions with Complete 
Solutions |latest update 
E = high priority groups on ___ -opposite sides 
Z = high priority groups on ___ -same side 
SN1 Reaction 
Substrate Preference -3 (fast) > 2 (slow) 
SN1 Reaction 
Reagent Required -Weak Nucleophile 
Is a SN1 reaction stepwise or concerted? -s
Exam (elaborations)
SN1/SN2 reactions and E1/E2 Questions with Complete 
Solutions |latest update 
Substitution Reaction 
replacing Leaving Group with a Nucleophile 
- Loss of LG 
- nucleophilic attack 
Substitution Reaction 2 mechanisms: 
1. concerted- 1 step 
2. stepwise-
SN1/SN2 reactions and E1/E2 Questions with Complete 
Solutions |latest update 
Substitution Reaction 
replacing Leaving Group with a Nucleophile 
- Loss of LG 
- nucleophilic attack 
Substitution Reaction 2 mechanisms: 
1. concerted- 1 step 
2. stepwise- 2 steps 
SN2 
substitution nucleophilic bimolecular
Exam (elaborations)
SN1, SN2, E1, E2, E1CB Reactions Questions with Complete 
Solutions |latest update 
SN2 
Substitution rxn 
Nucleophilic 
Bimolecular 
SN2 
Uses a nucleophile on an alkyl halide to conduct a substitution rxn 
SN2 
The kinetics depend on the substrate 
Invo
SN1, SN2, E1, E2, E1CB Reactions Questions with Complete 
Solutions |latest update 
SN2 
Substitution rxn 
Nucleophilic 
Bimolecular 
SN2 
Uses a nucleophile on an alkyl halide to conduct a substitution rxn 
SN2 
The kinetics depend on the substrate 
Involved in a slow SN2 reaction 
2 degree alkyl halide 
undergoes SN2 reactions only 
1 degree alkyl halide 
1 degree or 2 degree alkyl halides