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Exam (elaborations)
COMSAE 1 Exam Complete Test , Practice Questions, Verified Answer Key, and Study Guide for (Latest 2026 Edition)
COMSAE 1 Exam Complete Test , Practice Questions, Verified Answer Key, and Study Guide for (Latest 2026 Edition)
Exam (elaborations)
COMSAE 1 2026/2027 – Fully Explained Comprehensive Study Guide for COMLEX Level 1 Preparation
PopularComprehensive COMSAE 1 2026/2027 Study Guide designed for osteopathic medical students preparing for COMLEX-USA Level 1. Includes high-yield systems-based review, osteopathic principles and practice (OPP), pharmacology, microbiology, pathology, biochemistry, biostatistics, ethics, and integrated clinical reasoning. Features board-style practice questions with fully explained answers to strengthen test-taking strategy, diagnostic thinking, and exam performance.
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COMSAE / COMLEX MASTER DECK Exam Questions and Answers | latest Update | 100% Correct. post-flu pneumonia - Staph aureus COPD or smoker with rust-colored sputum and lobar pneumonia - Streptococcus pneumoniae alcoholic aspiration risk with c
COMSAE / COMLEX MASTER DECK Exam Questions and Answers | latest Update | 100% Correct. post-flu pneumonia - Staph aureus COPD or smoker with rust-colored sputum and lobar pneumonia - Streptococcus pneumoniae alcoholic aspiration risk with c
Exam (elaborations)
COMSAE 110 Exam questions and 
answers Graded A+ latest update 
Bacillus Anthracis Characteristics - Gram + rods in chains 
may manifest in cutaneous or pulmonary anthrax 
platelet membrane abnormalities present as - purpura 
epistaxis 
gingival bleeding
COMSAE 110 Exam questions and 
answers Graded A+ latest update 
Bacillus Anthracis Characteristics - Gram + rods in chains 
may manifest in cutaneous or pulmonary anthrax 
platelet membrane abnormalities present as - purpura 
epistaxis 
gingival bleeding 
anemia 
low hemoglobin
Exam (elaborations)
comsae 114 Exam questions and 
answers Graded A+ latest update 
thyroid storm (thyrotoxic crisis) 
fever, delirium, Atrial fibrillation, Heart failure, Hyperthermia 
Hyperthyroid physical findings (onycholysis, tremor, lid lag, goiter) 
- flaccid/proximal
comsae 114 Exam questions and 
answers Graded A+ latest update 
thyroid storm (thyrotoxic crisis) 
fever, delirium, Atrial fibrillation, Heart failure, Hyperthermia 
Hyperthyroid physical findings (onycholysis, tremor, lid lag, goiter) 
- flaccid/proximal muscle weakness 
Treat: beta blocker, thionamide, iodine after thionamide, 
glucocorticoid, coolin
Exam (elaborations)
COMSAE 110 Exam questions and 
answers Graded A+ latest update 
maxillary incisor innervation 
anterior superior alveolar nerve
COMSAE 110 Exam questions and 
answers Graded A+ latest update 
maxillary incisor innervation 
anterior superior alveolar nerve
Exam (elaborations)
COMSAE 110 Exam questions and 
answers Graded A+ latest update 
maxillary incisor innervation 
anterior superior alveolar nerve
COMSAE 110 Exam questions and 
answers Graded A+ latest update 
maxillary incisor innervation 
anterior superior alveolar nerve
Exam (elaborations)
COMSAE 113 Exam questions and 
answers Graded A+ latest update 
When is "blood cultures" typically the correct answer choice on step 2? 
If you suspected: sepsis 
- fever 
- hypotension 
- leukocytosis 
- infectious source 
- causing altered
COMSAE 113 Exam questions and 
answers Graded A+ latest update 
When is "blood cultures" typically the correct answer choice on step 2? 
If you suspected: sepsis 
- fever 
- hypotension 
- leukocytosis 
- infectious source 
- causing altered mental status. 
When is "creatine kinase leve
Exam (elaborations)
COMSAE 108b Exam questions 
and answers Graded A+ latest 
update 
Apgar scale 
What is dx test is done to diagnose NRDS? 
chest x-ray 
pulmonary embolism CT findings
COMSAE 108b Exam questions 
and answers Graded A+ latest 
update 
Apgar scale 
What is dx test is done to diagnose NRDS? 
chest x-ray 
pulmonary embolism CT findings
Exam (elaborations)
COMSAE Phase 1 Exam questions 
and answers Graded A+ latest 
update 
What is moa of ketamine 
NMDA receptor antagonist
COMSAE Phase 1 Exam questions 
and answers Graded A+ latest 
update 
What is moa of ketamine 
NMDA receptor antagonist
Exam (elaborations)
COMSAE 3 Exam questions and 
answers Graded A+ latest update 
Basal Nucleus of Meynert 
Acetylcholine (Ach) which is involved in learning, memory, muscle 
movements. 
Locus Ceruleus 
Norepinephrine (NE) which is involved in energy, concentration, 
cogniti
COMSAE 3 Exam questions and 
answers Graded A+ latest update 
Basal Nucleus of Meynert 
Acetylcholine (Ach) which is involved in learning, memory, muscle 
movements. 
Locus Ceruleus 
Norepinephrine (NE) which is involved in energy, concentration, 
cognition, arousal, anxiety. 
Nucleus Accumbens 
Dopamine (DA) and GABA, which are involved in reward/addiction, 
concentration, motivation, psychosis (dopamine) and sleep, anxiolytic, 
anticonvulsant (GABA). 
Raphe nucleus 
Serotonin (5-HT) which is i...
Exam (elaborations)
COMSAE 111 Exam questions and 
answers Graded A+ latest update 
Mandibular fracture, nerve that carries the pain sensation is the - 
 inferior alveolar N. Lingual N. branches off earlier and provides 
sensation to anterior 2/3 of tongue and floor of mouth
COMSAE 111 Exam questions and 
answers Graded A+ latest update 
Mandibular fracture, nerve that carries the pain sensation is the - 
 inferior alveolar N. Lingual N. branches off earlier and provides 
sensation to anterior 2/3 of tongue and floor of mouth. 
Patient is retching, vomiting small amount of blood, history of AUD. 
Nonpentrating mucosal tear of the posterior wall superior to the 
gastroesophageal junction that continues to the esophageal wall 
compromises -
Exam (elaborations)
COMSAE 111 Exam questions and 
answers Graded A+ latest update 
A 22-year-old woman presents to the emergency department with the 
complaint of an inability to pass stool despite the urgency to defecate. 
She reports that she frequently passes small amoun
COMSAE 111 Exam questions and 
answers Graded A+ latest update 
A 22-year-old woman presents to the emergency department with the 
complaint of an inability to pass stool despite the urgency to defecate. 
She reports that she frequently passes small amounts of blood and 
mucoid material during these episodes. She also mentions that her 
underwear occasionally becomes soiled with this material. An 
endoscopy reveals continuous and symmetrical inflammation of the 
involved segmen
Exam (elaborations)
COMSAE 115 Exam questions and 
answers Graded A+ latest update 
apprehension test - used to evaluate anterior glenohumeral 
shoulder instability 
- abduct the shoulder 90 degrees, flex the elbow to 90, and slowly 
externally rotate the shoulder while supp
COMSAE 115 Exam questions and 
answers Graded A+ latest update 
apprehension test - used to evaluate anterior glenohumeral 
shoulder instability 
- abduct the shoulder 90 degrees, flex the elbow to 90, and slowly 
externally rotate the shoulder while supporting the arm 
Yergason test - determines whether head of biceps is stable in 
the bicipital groove- pt fully flexes elbow while examiner grasps elbow 
and wrist- pt resists motion while examiner simultaneously extends 
elbow and externally rot...
Exam (elaborations)
COMSAE 114 Exam questions and 
answers Graded A+ latest update 
adult onset asthma, allergies, hemoptysis, eosinophilia with pulmonary 
infiltrates, elevated cratinine (glomerulonephritis), anemia, saddle nose 
deformity - granulomatosis with polyangitis
COMSAE 114 Exam questions and 
answers Graded A+ latest update 
adult onset asthma, allergies, hemoptysis, eosinophilia with pulmonary 
infiltrates, elevated cratinine (glomerulonephritis), anemia, saddle nose 
deformity - granulomatosis with polyangitis 
- small vessel vasculitis seen with hx of asthma 
- saddle nose deformity is due to destruction of the septal cartilage 
which collapses the bridge of the nose 
vastus medialis weakness, crep
Exam (elaborations)
Comsae 111 Exam questions and 
answers Graded A+ latest update 
What radiographic finding is classic for spina bifida occulta? - A 
midline posterior vertebral arch defect caused by failure of fusion, 
often seen as lucency through a spinous process. 
How
Comsae 111 Exam questions and 
answers Graded A+ latest update 
What radiographic finding is classic for spina bifida occulta? - A 
midline posterior vertebral arch defect caused by failure of fusion, 
often seen as lucency through a spinous process. 
How do spina bifida occulta and ankylosing spondylitis differ on 
imaging? - Spina bifida occulta causes a posterior arch defect; 
ankylosing spondylitis causes sacroiliitis, syndesmophytes, and a 
bamboo spine. 
Which nerve carries pain from the m...
Exam (elaborations)
COMSAE Drugs Exam questions 
and answers Graded A+ latest 
update 
Warfarin- Mechanism - Interferes w/ vitamin K dependent 
clotting factors (II, VII, IX, X, C, S) 
Warfarin- Pathway, effect on PT/INR - Extrinsic factor, increased 
PT 
Warfarin- Clinical
COMSAE Drugs Exam questions 
and answers Graded A+ latest 
update 
Warfarin- Mechanism - Interferes w/ vitamin K dependent 
clotting factors (II, VII, IX, X, C, S) 
Warfarin- Pathway, effect on PT/INR - Extrinsic factor, increased 
PT 
Warfarin- Clinical Use -
Exam (elaborations)
COMSAE Drugs Exam questions 
and answers Graded A+ latest 
update 
Warfarin- Mechanism - Interferes w/ vitamin K dependent 
clotting factors (II, VII, IX, X, C, S) 
Warfarin- Pathway, effect on PT/INR - Extrinsic factor, increased 
PT 
Warfarin- Clinical
COMSAE Drugs Exam questions 
and answers Graded A+ latest 
update 
Warfarin- Mechanism - Interferes w/ vitamin K dependent 
clotting factors (II, VII, IX, X, C, S) 
Warfarin- Pathway, effect on PT/INR - Extrinsic factor, increased 
PT 
Warfarin- Clinical Use - Chronic anticoagulation 
Warfarin- Pregnancy - CI in pre
Exam (elaborations)
COMSAE 1 Exam questions and 
answers Graded A+ latest update 
Hyperimmunoglobulinemia E (Job syndrome) 
An autosomal dominant condition characterized by the triad of eczema, 
eosinophilia, and recurrent skin and pulmonary infections. 
It is also associate
COMSAE 1 Exam questions and 
answers Graded A+ latest update 
Hyperimmunoglobulinemia E (Job syndrome) 
An autosomal dominant condition characterized by the triad of eczema, 
eosinophilia, and recurrent skin and pulmonary infections. 
It is also associated with multiple connective tissue and skeletal 
abnormalities, including scoliosis, hyperextensibility, pathologic 
fractures, retained primary dentition, craniosynostosis, and vascular 
abnormalities 
Nitroblue Tetrazolium Dye Test 
It is used ...
Exam (elaborations)
comsae 114 Exam questions and 
answers Graded A+ latest update 
thyroid storm (thyrotoxic crisis) 
fever, delirium, Atrial fibrillation, Heart failure, Hyperthermia 
Hyperthyroid physical findings (onycholysis, tremor, lid lag, goiter) 
- flaccid/proximal
comsae 114 Exam questions and 
answers Graded A+ latest update 
thyroid storm (thyrotoxic crisis) 
fever, delirium, Atrial fibrillation, Heart failure, Hyperthermia 
Hyperthyroid physical findings (onycholysis, tremor, lid lag, goiter) 
- flaccid/proximal muscle weakness 
Treat: beta blocker, thionamide, iodine after thionamide, 
glucocorticoid, cooling/supportive care 
Joe Basedow phenomenon 
iodine induced hyperthyroidism 
Occurs after: 
Iodinated contrast 
Amiodarone 
Excess iodine 
It can pr...
Exam (elaborations)
COMSAE #3 Exam questions and 
answers Graded A+ latest update 
Which Ovarian Tumor ? 
-Tumor markers are hCG, LDH 
-Associated with Tur
COMSAE #3 Exam questions and 
answers Graded A+ latest update 
Which Ovarian Tumor ? 
-Tumor markers are hCG, LDH 
-Associated with Tur
Exam (elaborations)
COMSAE 111_26Qs Exam 
questions and answers Graded A+ 
latest update 
Pancreas Chapman Point - Anterior = Right 7th ICS; Posterior = 
Right btwn T7-T8 
Kidney Chapman Point - Anterior: 1 inch lateral and 1 inch 
superior to the umbilicus 
Posterior: Inter
COMSAE 111_26Qs Exam 
questions and answers Graded A+ 
latest update 
Pancreas Chapman Point - Anterior = Right 7th ICS; Posterior = 
Right btwn T7-T8 
Kidney Chapman Point - Anterior: 1 inch lateral and 1 inch 
superior to the umbilicus 
Posterior: Intertransverse space b