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BMD 410 Lecture 5 study guide 2024
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What is the proteome? - functional representation of the genome -entire set of proteins expressed and modified by a cell under a particular set of biochemical conditions. -not all proteins are expressed in every cell How can we analyze the proteome? - Isolate, characterize and catalog the proteins Characterizing proteins - 1. Get access (bust open cell) 2. Purify sample 3. Assess the purity of the sample 4. Determine structure by NMR or X-ray crystallography What is the purpose...
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