PHRC 4101 (PHRC)
St. Louis College Of Pharmacy
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Class notes
Isotonic Solutions
St. Louis College Of Pharmacy
PHRC 4101
An Isotonic Solution has the same osmotic pressure as bodily 
fluids (blood or tears) 
• 0.9% (w/v) sodium chloride is considered isotonic with bodily 
fluids 
– Normal Saline includes 0.9 grams of Sodium per 100mls 
• Drug solutions that often need to be isotonic include: 
– Parenteral (IV) preparations 
– Ophthalmic solution
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