Tyrosine kinase Samenvattingen, Notities en Examens

CMMB 403 Midterm 1 Question and answers already passed 2024Describe the RTK signal transduction pathway when activated by the FGF ligand FGF ligand dimerizes RTK receptor. Receptor is phorphorylated and attracts adaptor/GEF. GEF begins phosphorylation cascade: GEF to Ras to Raf to Mek to Erk to TF. TF transcribes gene Describe the JAK-STAT pathway when activated by FGF FGF ligand dimerizes RTK. JAK2 proteins cross-phosphorylate. Both JAK2s phosphorylate a STAT5 (which is a cytoplasmic tyr...

BIOS-252: ANATOMY & PHYSIOLOGY II 1.What type of hormones bind to receptors located on the cell membrane? -water-soluble hormones, such as insulin and epinephrine -lipid-soluble hormones, such as thyroid hormones and cortisol water-soluble hormones, such as insulin and epinephrine 2.Which intracellular substance degrades cAMP, thus inactivating the response to a hormone? -phospholipase C -adenylate cyclase -phosphodiesterase -protein kinase C phosphodiesterase Brainpower / 3.Growth...

Key drugs that can cause hypothyroidism - ️️"I TALC" Interferons Tyrosine Kinase Inhibitors Amiodarone Lithium Carbamazepine Conditions: Hashimoto's disease Levothyroxine IV:PO - ️️0.75:1 (IV:PO) Full replacement dose levothyroxine - ️️1.6 mcg/kg/day (IBW) If known CAD: start with 12.5-25 mcg daily Levothyroxine tablet colors - ️️Orangutans Will Vomit On You Right Before They Become Large Proud Giants 25 Orange 50 White (no dye) 75 Violet 88 Olive 100 Ye...

CPPS 325 FINAL EXAM QUESTIONS WITH CORRECT ANSWERS 2023/2024 Graded A+. What is the only example of conformational change activation? - Correct Answer-Insulin receptor kinase. All other RTKs are activated through forms of dimerization. What are the two forms of dimerization? - Correct Answer-i) Receptors exist as unactivated dimers until ligand binds (Twist theory) ii) exist as monomers that are brought together and activated by ligand binding. What is the most common method of dimerizatio...

Fundamentals of Chemotherapy Immunotherapy Administration Paclitaxel -plant alkaloid -common in combo with cisplatin -treats: ovarian, breast, lung CA no surgery, AIDS related kaposi sarcoma -admin IV only in filter -anaphylaxis, pre-medicate w/pepcid, benadryl, dex Etoposide -Plant alkaloids -treats: testicular and small cell Lung, off-labels too -IV only, (30-60 min) -can cause anaphylaxis and hypotension Vincristine -plant alkaloid -treat: lymphoma, leukemia, neuroblastoma, rhabdomyosarcoma ...

BIOCHEM Midterm Exam 2 Questions with Verified Answers| 100% Correct| 100% Score Which of the following enzymes is part of both the TCA cycle and ETC? - Succinate dehydrogenase In the case of deficiency in phenylalanine hydroxlase which of the following amino acids will become essential - Tyrosine HFI is a rare recessive disorder. Which of the following is not a consequence of this enzyme deficiency? - They will have low blood sugar (hypoglycemia), especially after eating fruits, fructose,...

PHYS 506 Anatomy and Physiology Endocrine (Pancreatic Islet Cells) MCQs Answers 2023/24 Pancreatic Islet Cells 186. A patient presents with Whipple triad, including plasma glucose < 60 mg/dL, symptomatic hypoglycemia, and improvement of symptoms with administration of glucose. CT of the abdomen is suggestive of islet cell carcinoma. Which of the following best describes the islets of Langerhans? (A) They are found primarily in the head of the pancreas. (B) They constitute approximately...

WGU D027 Exam Questions & Answers Latest Updated 2023 As an advanced practice nurse, you want to learn more about the CDC's initiatives relative to asthma care and management in order to advocate for asthma sufferers at the state legislative level. Your goal is to reduce medications costs to patients. Which CDC recommendation supports your goal? a. The CDC recommends that payers and employers promote healthy workspaces to decrease environmental trigger exposures. b. The CDC recommends th...

CPPS 325 FINAL EXAM With Updated &Verified Answers 2023/2024 What are the 5 well-known enzyme-linked cell surface receptors? Correct Answer 1. Receptor Guanylyl Cyclase: produces cGMP 2. RTK: phosphorylate tyrosine residues leading to association of signalling molecules and cascade 3. TK Associated Receptors: associate with proteins having TK activity 4. Receptor Tyrosine Phosphates: Removes phosphate on tyrosine residues 5. Receptor Serine/Threonine Kinases: phosphorylate specific Se...

CPPS 325 FINAL EXAM Questions and Answers 2023 What are the 5 well-known enzyme-linked cell surface receptors? 1. Receptor Guanylyl Cyclase: produces cGMP 2. RTK: phosphorylate tyrosine residues leading to association of signalling molecules and cascade 3. TK Associated Receptors: associate with proteins having TK activity 4. Receptor Tyrosine Phosphates: Removes phosphate on tyrosine residues 5. Receptor Serine/Threonine Kinases: phosphorylate specific Serine/Threonine residues on IC sign...