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APHON CHEMO AGENTS & CLASSIFICATIONS EXAM QUESTIONS AND ANSWERS 100% CORRECT!!
  • Exam (elaborations)

    APHON CHEMO AGENTS & CLASSIFICATIONS EXAM QUESTIONS AND ANSWERS 100% CORRECT!!

  • alkylating agents - ANSWER non-specific. although most active in resting phase. cause dna strand breaks antimetabolites - ANSWER interfere w/ cell metabolism by inhibiting enzyme production or producing nonfunctional end product. interrupts protein synthesis, rna, or dna anthracyclines - ANSWER prevent rejoining of cleaved dna strands by inhibiting topoisomerase ii (dna untangling enzyme). also forms hydroxyl radicals which attack dna/cell membrane lipids (cardiotoxic) give cardioprotecti...
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APHON Chemo Agents & Classifications Questions with Accurate Answers
  • Exam (elaborations)

    APHON Chemo Agents & Classifications Questions with Accurate Answers

  • cell cycle specific - ANSWERSaffective during specific phase, w/ maximal effect on rapidly dividing cells cell cycle non-specific - ANSWERSdisregard phase. dose dependent. effective on slow growing cancer cells b/c cytotoxic in resting phase as well. degree of cell kill directly correlates to dose administered alkylating agents - ANSWERSnon-specific. although most active in resting phase. cause dna strand breaks antimetabolites - ANSWERSinterfere w/ cell metabolism by inhibiting enzyme ...
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