NUR 521 ADV PHARM EXAM 1 Newest 2025 Complete Questions And
Correct Answers |Already Graded A+||Brand New!!
What important teaching should be provided for the drug Cyclobenzaprine? What is serotonin
syndrome? What is s/s? What is AE of this drug? - ANSWER-Cyclobenzaprine (Amrix)
Centrally Acting Muscle Relaxer - Work in brainstem to reduce tonic motor activity
Teaching: Fall risk, CNS depressant, S/S of serotonin syndrome
Serotonin Syndrome AE: AMS (agitation, restlessness, confusion, hallucinations), Autonomic Nervous
System (tachycardia, hyperthermia, diaphoresis, HTN, pupil dilation), Muscular Sx (tremor, hyperreflexia,
ataxia, muscle twitching, rigidity)
AE: CNS depression, anticholinergic sx, dysrhythmias
What is a contraindication of Dantrolene? BBW? - ANSWER-Dantrolene (Dantrium)
Direct Acting Muscle Relaxant
CI: Liver disease
BBW: Fatal Hepatotoxiticity
What is the BBW associated with Baclofen? What should the provider know about administration of this
drug? - ANSWER-Baclofen (Lioresal)
Centrally Acting Muscle Relaxer
,BBW: abrupt withdrawal of intrathecal baclofen - high fever, AMS, exaggerated rebound spasticity,
muscle rigidity that can advance to MODS and rhabdo
Provider should know:
Caution with other CNS depressants, history of BPH, psych conditions. Used to reduce spasticity.
We discussed two prototype drugs used to treat seizures. Compare and contrast these drugs. How do
they work? What type of seizure do they treat? What precautions should be taken? What would you
teach your patient? - ANSWER-Phentoin (Dilantin)
Traditional Drug Class
MOA: inhibition of Na channels resulting in decreased action potentials
Treat partial and generalized tonic-clonic seizures (NOT absence seizures)
CI: HLA B1502 mutation, pregnancy, IV dose can cause hypotension/dysrhythmias
Education: dont stop abruptly, seizure chart, plasma level monitoring, folic acid during pregnancy, good
oral hygiene
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Oxycarbazepine (Trileptal)
Newer Drug Class
MOA: block Na channels in neuronal membranes, stabilizing hyper neurons
Treat partial seizures
, -Hyponatremia can occur, especially with diuretics. SJS/TEN can occur.
-Same pt ed
**most important rule with antiseizure drugs is that they must be withdrawn slowly (6 weeks to several
months)
· What drug can you prescribe to treat restless leg syndrome? How does it work? What should you teach
your patient? - ANSWER-Ropinirole (Requip)
Dopamine Agonist - binds to D2 and D3 receptors
Patient teaching:
· Take with food to minimize N & V
· Orthostatic hypotension
· Movement disorders
· Hallucinations
· No pregnancy
· Risk for compulsive behaviors
DOC for parkinsons disease - how does it work? How long does it take to work? How would you know its
working? What should you teach your pt? - ANSWER-Levodopa/Carbidopa
How it works: oincreases dopamine synthesis
O After uptake in brain, converts to active form of dopamine restoring balance between dopamine and
acetylcholine
How long does it take to work: full therapeutic response can take a few months
Correct Answers |Already Graded A+||Brand New!!
What important teaching should be provided for the drug Cyclobenzaprine? What is serotonin
syndrome? What is s/s? What is AE of this drug? - ANSWER-Cyclobenzaprine (Amrix)
Centrally Acting Muscle Relaxer - Work in brainstem to reduce tonic motor activity
Teaching: Fall risk, CNS depressant, S/S of serotonin syndrome
Serotonin Syndrome AE: AMS (agitation, restlessness, confusion, hallucinations), Autonomic Nervous
System (tachycardia, hyperthermia, diaphoresis, HTN, pupil dilation), Muscular Sx (tremor, hyperreflexia,
ataxia, muscle twitching, rigidity)
AE: CNS depression, anticholinergic sx, dysrhythmias
What is a contraindication of Dantrolene? BBW? - ANSWER-Dantrolene (Dantrium)
Direct Acting Muscle Relaxant
CI: Liver disease
BBW: Fatal Hepatotoxiticity
What is the BBW associated with Baclofen? What should the provider know about administration of this
drug? - ANSWER-Baclofen (Lioresal)
Centrally Acting Muscle Relaxer
,BBW: abrupt withdrawal of intrathecal baclofen - high fever, AMS, exaggerated rebound spasticity,
muscle rigidity that can advance to MODS and rhabdo
Provider should know:
Caution with other CNS depressants, history of BPH, psych conditions. Used to reduce spasticity.
We discussed two prototype drugs used to treat seizures. Compare and contrast these drugs. How do
they work? What type of seizure do they treat? What precautions should be taken? What would you
teach your patient? - ANSWER-Phentoin (Dilantin)
Traditional Drug Class
MOA: inhibition of Na channels resulting in decreased action potentials
Treat partial and generalized tonic-clonic seizures (NOT absence seizures)
CI: HLA B1502 mutation, pregnancy, IV dose can cause hypotension/dysrhythmias
Education: dont stop abruptly, seizure chart, plasma level monitoring, folic acid during pregnancy, good
oral hygiene
------------------
Oxycarbazepine (Trileptal)
Newer Drug Class
MOA: block Na channels in neuronal membranes, stabilizing hyper neurons
Treat partial seizures
, -Hyponatremia can occur, especially with diuretics. SJS/TEN can occur.
-Same pt ed
**most important rule with antiseizure drugs is that they must be withdrawn slowly (6 weeks to several
months)
· What drug can you prescribe to treat restless leg syndrome? How does it work? What should you teach
your patient? - ANSWER-Ropinirole (Requip)
Dopamine Agonist - binds to D2 and D3 receptors
Patient teaching:
· Take with food to minimize N & V
· Orthostatic hypotension
· Movement disorders
· Hallucinations
· No pregnancy
· Risk for compulsive behaviors
DOC for parkinsons disease - how does it work? How long does it take to work? How would you know its
working? What should you teach your pt? - ANSWER-Levodopa/Carbidopa
How it works: oincreases dopamine synthesis
O After uptake in brain, converts to active form of dopamine restoring balance between dopamine and
acetylcholine
How long does it take to work: full therapeutic response can take a few months
