UIUC MCB 450 EXAM 1 (HAS LON CAPA AND ICLICKER QUESTIONS) | 2025/2026 UPDATE |
QUESTIONS AND ANSWERS | WITH COMPLETE SOLUTION!!
Biomolecules can be divided into four different classes. Which of the following is NOT a major class of
biomolecule? - (ANSWER)Fatty Acids
Which of the following molecules are the major components of the collagen? - (ANSWER)proteins
Water is said to be highly cohesive because water molecules interact with one another through: -
(ANSWER)hydrogen bonds
Which of the following is considered a noncovalent bond? - (ANSWER)-electrostatic interactions
-hydrogen bonds
-Van der Waals interactions
-ALL OF THE ABOVE
What is the [A-]/[HA] ratio when the weak acid is in a solution two pH units above its pKa? -
(ANSWER)100:1
Brownian motion is due to: - (ANSWER)The random fluctuation of the energy content of the
environment and thermal noise
Consider a biochemical reaction that is taking place in a 0.1 M buffer. The initial pH is 7.4, and the pKa of
the buffer is 7.2. If, in a final reaction volume of 1.0 mL, 10 micromol of protons are generated, what
would be the final pH of the solution? - (ANSWER)7.22
Solution X is at a pH of 3; solution Y is at a pH of 8. Which of the following statements is TRUE? -
(ANSWER)solution X contains more protons than solution Y
What are the primary chemical components present in a phosphate buffer at pH 7.4? - (ANSWER)H₂PO₄⁻
and HPO₄ ⁻²
, UIUC MCB 450 EXAM 1 (HAS LON CAPA AND ICLICKER QUESTIONS) | 2025/2026 UPDATE |
QUESTIONS AND ANSWERS | WITH COMPLETE SOLUTION!!
Which of the following characterize α-helix regions of proteins? - (ANSWER)They are formed principally
by hydrogen bonds between a carbonyl oxygen atom in one peptide bond and the amide hydrogen from
a different peptide bond.
Autopsies of patients with Alzheimer disease show protein aggregates called neurofibrillary tangles and
neuritic plaques in various regions of the brain. These plaques exhibit the characteristic staining of
amyloid. Which of the following structural features is the most likely characteristic of at least one
protein in these plaques? - (ANSWER)A high content of beta pleated sheet structure
Which of the following secondary structures is most likely to be found in a membrane-embedded
portion of a protein? - (ANSWER)an alpha helix composed entirely of hydrophobic residues
Which of the following statements regarding peptide bonds is least accurate? - (ANSWER)favored
conformation of peptide bonds is with the sequential alpha carbons in the cis position
Which is an appropriate statement of involvement of the hydrophobic effect in protein folding? -
(ANSWER)Nonpolar portions of the molecule associate with one another in the interior of the protein.
All of the following would disrupt quaternary structure except: - (ANSWER)Treat with ascorbic acid
(vitamin C).
The process of digestion in the stomach is carried out in two main ways. One way involves the
_____environment that exists in the stomach. - (ANSWER)low pH
The pancreas releases _________ to buffer the pH of the stomach juices. - (ANSWER)NaHCO3
Pepsin requires _________ to achieve activity. - (ANSWER)-zymogen activation
-low pH
-Partial denaturation of protein
QUESTIONS AND ANSWERS | WITH COMPLETE SOLUTION!!
Biomolecules can be divided into four different classes. Which of the following is NOT a major class of
biomolecule? - (ANSWER)Fatty Acids
Which of the following molecules are the major components of the collagen? - (ANSWER)proteins
Water is said to be highly cohesive because water molecules interact with one another through: -
(ANSWER)hydrogen bonds
Which of the following is considered a noncovalent bond? - (ANSWER)-electrostatic interactions
-hydrogen bonds
-Van der Waals interactions
-ALL OF THE ABOVE
What is the [A-]/[HA] ratio when the weak acid is in a solution two pH units above its pKa? -
(ANSWER)100:1
Brownian motion is due to: - (ANSWER)The random fluctuation of the energy content of the
environment and thermal noise
Consider a biochemical reaction that is taking place in a 0.1 M buffer. The initial pH is 7.4, and the pKa of
the buffer is 7.2. If, in a final reaction volume of 1.0 mL, 10 micromol of protons are generated, what
would be the final pH of the solution? - (ANSWER)7.22
Solution X is at a pH of 3; solution Y is at a pH of 8. Which of the following statements is TRUE? -
(ANSWER)solution X contains more protons than solution Y
What are the primary chemical components present in a phosphate buffer at pH 7.4? - (ANSWER)H₂PO₄⁻
and HPO₄ ⁻²
, UIUC MCB 450 EXAM 1 (HAS LON CAPA AND ICLICKER QUESTIONS) | 2025/2026 UPDATE |
QUESTIONS AND ANSWERS | WITH COMPLETE SOLUTION!!
Which of the following characterize α-helix regions of proteins? - (ANSWER)They are formed principally
by hydrogen bonds between a carbonyl oxygen atom in one peptide bond and the amide hydrogen from
a different peptide bond.
Autopsies of patients with Alzheimer disease show protein aggregates called neurofibrillary tangles and
neuritic plaques in various regions of the brain. These plaques exhibit the characteristic staining of
amyloid. Which of the following structural features is the most likely characteristic of at least one
protein in these plaques? - (ANSWER)A high content of beta pleated sheet structure
Which of the following secondary structures is most likely to be found in a membrane-embedded
portion of a protein? - (ANSWER)an alpha helix composed entirely of hydrophobic residues
Which of the following statements regarding peptide bonds is least accurate? - (ANSWER)favored
conformation of peptide bonds is with the sequential alpha carbons in the cis position
Which is an appropriate statement of involvement of the hydrophobic effect in protein folding? -
(ANSWER)Nonpolar portions of the molecule associate with one another in the interior of the protein.
All of the following would disrupt quaternary structure except: - (ANSWER)Treat with ascorbic acid
(vitamin C).
The process of digestion in the stomach is carried out in two main ways. One way involves the
_____environment that exists in the stomach. - (ANSWER)low pH
The pancreas releases _________ to buffer the pH of the stomach juices. - (ANSWER)NaHCO3
Pepsin requires _________ to achieve activity. - (ANSWER)-zymogen activation
-low pH
-Partial denaturation of protein
