The process that drives an increase in antibody affinity for antigen is known as _____
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Affinity maturation
Recombination of a V, a D and a J segment give rise to the ______ region of the heavy
chain
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Variable
,Receptors such as Toll-like receptors (TLRs), NOD-like receptors (NLRs), RIG-like
receptors (RLRs), scavenger receptors are ______ receptors. These receptors on
immune cells allow the detection of pathogens by binding to _______.
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1. Pattern Recognition Receptors (PRRs)
2. PAMPs
In humans ____ and ____ best mediate opsonization
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IgG1 and IgG3
The process of _______ results in the recombination of gene segments of the T-cell
receptor and immunoglobulin genes giving rise to lymphocytes with the unique
specificities for antigens.
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VDJ Recombination
Naive T cells do not express
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, CD25
IFN-gamma
FasL
Which of the following is not used to generate diversity in the TCR repertoire:
A. Presence of multiple variable gene segments that can be assembled in multiple
different combinations
B. Addition of N nucleotides that are not encoded in the germ line
C. Somatic hypermutation
D. Exonuclease trimming of excess nucleotides at variable segment junctions
E. Ability to pair a single chain with a different beta chain
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C. Somatic hypermutation
Which of the following is not a characteristic of inflammation?
A. inactivation of macrophages
B. increased vascular permeability
C. vasodilation
D. pain
E. influx of leukocytes
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A. inactivation of macrophages
, An antimicrobial peptide that protects epithelial surfaces from pathogens is:
a. Glycoprotein
b. Defensin
c. Proteoglycan
d. Lysozyme
e. Sebum
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b. Defensin
The process of _____ results in change in the constant region of the heavy-chain of
antibodies, causing a change in the effector function and transport properties of
antibodies.
a. complement fixation
b. neutralization
c. isotype switching
d. somatic hypermutation
e. somatic recombination
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c. isotype switching
Which of the following is the correct relationship? _________ on _________ recognize _________
on _________.
a. PRRs : macrophages; PAMPs : neutrophils
b. PRRs : pathogen; PAMPs : macrophages
c. PAMPs : macrophages; PRRs : pathogens
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Affinity maturation
Recombination of a V, a D and a J segment give rise to the ______ region of the heavy
chain
Give this one a try later!
Variable
,Receptors such as Toll-like receptors (TLRs), NOD-like receptors (NLRs), RIG-like
receptors (RLRs), scavenger receptors are ______ receptors. These receptors on
immune cells allow the detection of pathogens by binding to _______.
Give this one a try later!
1. Pattern Recognition Receptors (PRRs)
2. PAMPs
In humans ____ and ____ best mediate opsonization
Give this one a try later!
IgG1 and IgG3
The process of _______ results in the recombination of gene segments of the T-cell
receptor and immunoglobulin genes giving rise to lymphocytes with the unique
specificities for antigens.
Give this one a try later!
VDJ Recombination
Naive T cells do not express
Give this one a try later!
, CD25
IFN-gamma
FasL
Which of the following is not used to generate diversity in the TCR repertoire:
A. Presence of multiple variable gene segments that can be assembled in multiple
different combinations
B. Addition of N nucleotides that are not encoded in the germ line
C. Somatic hypermutation
D. Exonuclease trimming of excess nucleotides at variable segment junctions
E. Ability to pair a single chain with a different beta chain
Give this one a try later!
C. Somatic hypermutation
Which of the following is not a characteristic of inflammation?
A. inactivation of macrophages
B. increased vascular permeability
C. vasodilation
D. pain
E. influx of leukocytes
Give this one a try later!
A. inactivation of macrophages
, An antimicrobial peptide that protects epithelial surfaces from pathogens is:
a. Glycoprotein
b. Defensin
c. Proteoglycan
d. Lysozyme
e. Sebum
Give this one a try later!
b. Defensin
The process of _____ results in change in the constant region of the heavy-chain of
antibodies, causing a change in the effector function and transport properties of
antibodies.
a. complement fixation
b. neutralization
c. isotype switching
d. somatic hypermutation
e. somatic recombination
Give this one a try later!
c. isotype switching
Which of the following is the correct relationship? _________ on _________ recognize _________
on _________.
a. PRRs : macrophages; PAMPs : neutrophils
b. PRRs : pathogen; PAMPs : macrophages
c. PAMPs : macrophages; PRRs : pathogens
