FOR
UNDERSTANDING ANATOMY &
PHYSIOLOGY:
A VISUAL, AUDITORY, INTERACTIVE
APPROACH
4TH EDITION
BY
GALE SLOAN THOMPSON
WITH
RATIONALES
, CHAPTER 1 — INTRODUCTION TO ANATOMY & PHYSIOLOGY /
HOMEOSTASIS
1. A nurse teaches a patient about homeostasis. Which statement best describes
homeostasis?
A. The ability of the body to keep all variables at a single fixed value.
B. The process of returning the internal environment to a narrow, stable
range.
C. A mechanism that only operates during illness.
D. Rapid, unpredictable changes in body systems.
Answer: B.
Rationale: Homeostasis is the process by which the body maintains internal
stability (a narrow, stable range) despite external changes. It is not a single fixed
value for all variables (A is incorrect), it operates continuously (C incorrect), and it
is not rapid, unpredictable changes (D incorrect).
2. A patient’s blood glucose rises after a meal. Which mechanism is an
example of a negative feedback response to this change?
A. Increased glucagon secretion from alpha cells.
B. Increased insulin secretion from beta cells.
C. Activation of the sympathetic nervous system to raise blood glucose.
D. Vasodilation of peripheral blood vessels.
Answer: B.
Rationale: Negative feedback reduces the deviation from normal. Increased
insulin lowers blood glucose back toward normal. Glucagon raises glucose (A
wrong), sympathetic activation raises glucose (C wrong), vasodilation is unrelated
(D wrong).
3. A clinician explains control centers in homeostatic loops. Which structure
often acts as the control center for temperature regulation?
A. Cerebellum
B. Hypothalamus
C. Medulla oblongata
D. Pituitary gland
, Answer: B.
Rationale: The hypothalamus is the primary thermoregulatory center. Cerebellum
is for coordination (A), medulla for vital reflexes (C), pituitary releases hormones
but isn't the primary temperature control center (D).
4. A patient has lost a lot of blood and their blood pressure drops. Which
immediate compensatory response is characteristic of a short-term
homeostatic mechanism?
A. Increased erythropoietin release from kidneys.
B. Baroreceptor-mediated sympathetic activation causing vasoconstriction.
C. Increased synthesis of albumin in the liver.
D. Remodeling of blood vessels.
Answer: B.
Rationale: Short-term compensation to maintain blood pressure includes
baroreceptor reflexes increasing sympathetic activity and vasoconstriction.
Erythropoietin (A) is longer-term; albumin synthesis (C) and remodeling (D) are
not immediate.
5. Which is an example of positive feedback?
A. Decrease in body temperature stimulating shivering.
B. Blood glucose rise stimulating insulin release.
C. Oxytocin release causing uterine contractions, which increase oxytocin
release.
D. Increased arterial CO₂ stimulating increased ventilation until CO₂
normalizes.
Answer: C.
Rationale: Positive feedback amplifies a change: oxytocin → contractions →
more oxytocin. The others are negative feedback examples.
6. A client receives a medication that blocks receptors in an efferent pathway
of a reflex arc. Which part of the reflex arc is affected?
A. Sensory receptor
B. Afferent neuron
C. Integrating center
D. Motor (efferent) neuron