APHON: Pediatric Chemo and Biotherapy
1. Inducing _________ in malignant cells or killing malig- Apoptosis, Necrosis
nant cells via _________ is the goal of many cancer treat-
ments
2. Markers used to determine the type of cell that has Cluster of Differentiation
become malignant. (CD) Markers
3. 5 Chemotherapy Drugs that contribute to Heart prob- Daunorubicin, Doxoru-
lems bicin, Idarubicin, Mitox-
antrone, Cytoxan (HSCT)
4. 3 Main Chemotherapies to cause Neurotoxicity Vinca Alkaloids, Nelara-
bine, Ifosfomide
5. 2 Chemotherapy Drugs that cause Ototoxicity Carboplatin, Cisplatin
6. 2 Chemotherapy Drugs that Cause Capillary Leak/Pul- Clofarabine, Cytarabine
monary Edema
7. Main Chemotherapy Drug that causes Diarrhea Irinotecan
8. Main Chemotherapy Drug that causes Pulmonary Fi- Bleomycin
brosis
9. Biggest Chemotherapy Drug Class that causes Infertil- Alkylating Agents
ity
10. Main Chemotherapy Drug that causes Conjunctivi- Cytarabine
tis/Photosensitivity
11. 3 Chemotherapy Drugs that cause Hyperpigmentation Busulfan, Melphalan,
Thiotepa
12. 8 Chemotherapy Drugs that are Highly Vesicants
1/6
, APHON: Pediatric Chemo and Biotherapy
1. Vincristine
2. Vinblastine
3. Navalbine
4. Actinomycin
5. Daunorubicin
6. Idarubicin
7. Doxorubicin
8. Mitoxantrone
13. 11 Chemotherapy Drugs that cause Mucositis Actinomycin, Busul-
fan, Cytarabine, MTX,
Dauno/Doxo/Ida, 5-FU,
Melphalan, Mitoxantrone,
Paciltaxel
14. Biggest Chemotherapy Drugs to cause Constipation Vinca Alkaloids
15. 6 Chemotherapy Drugs to cause Hepatotoxicity Busulfan, MTX, Mer-
captopurine, Thoguanine,
Dauno/Doxo, Etoposide
16. 2 Chemotherapy Drug to cause Pancreatitits Asparaginase, Steroids
17. 2 Chemotherapy Drugs to cause Hemorrhagic Cystitis Cytoxan, Ifosfamide
18. 5 Nephrotoxic Chemotherapy Drugs MTX, Ifosfamide, Cytoxan,
Carboplatin, Cisplatin
19. 5 Chemotherapy Drugs to Cause Hypersensitivity Asparaginase, Car-
boplatin, Etoposide,
Bleomycin, Pailitaxel
20. 2 Biotherapy Drugs that Cause Neurotoxicity Tisagenlecleucel, Blinatu-
momab
2/6
1. Inducing _________ in malignant cells or killing malig- Apoptosis, Necrosis
nant cells via _________ is the goal of many cancer treat-
ments
2. Markers used to determine the type of cell that has Cluster of Differentiation
become malignant. (CD) Markers
3. 5 Chemotherapy Drugs that contribute to Heart prob- Daunorubicin, Doxoru-
lems bicin, Idarubicin, Mitox-
antrone, Cytoxan (HSCT)
4. 3 Main Chemotherapies to cause Neurotoxicity Vinca Alkaloids, Nelara-
bine, Ifosfomide
5. 2 Chemotherapy Drugs that cause Ototoxicity Carboplatin, Cisplatin
6. 2 Chemotherapy Drugs that Cause Capillary Leak/Pul- Clofarabine, Cytarabine
monary Edema
7. Main Chemotherapy Drug that causes Diarrhea Irinotecan
8. Main Chemotherapy Drug that causes Pulmonary Fi- Bleomycin
brosis
9. Biggest Chemotherapy Drug Class that causes Infertil- Alkylating Agents
ity
10. Main Chemotherapy Drug that causes Conjunctivi- Cytarabine
tis/Photosensitivity
11. 3 Chemotherapy Drugs that cause Hyperpigmentation Busulfan, Melphalan,
Thiotepa
12. 8 Chemotherapy Drugs that are Highly Vesicants
1/6
, APHON: Pediatric Chemo and Biotherapy
1. Vincristine
2. Vinblastine
3. Navalbine
4. Actinomycin
5. Daunorubicin
6. Idarubicin
7. Doxorubicin
8. Mitoxantrone
13. 11 Chemotherapy Drugs that cause Mucositis Actinomycin, Busul-
fan, Cytarabine, MTX,
Dauno/Doxo/Ida, 5-FU,
Melphalan, Mitoxantrone,
Paciltaxel
14. Biggest Chemotherapy Drugs to cause Constipation Vinca Alkaloids
15. 6 Chemotherapy Drugs to cause Hepatotoxicity Busulfan, MTX, Mer-
captopurine, Thoguanine,
Dauno/Doxo, Etoposide
16. 2 Chemotherapy Drug to cause Pancreatitits Asparaginase, Steroids
17. 2 Chemotherapy Drugs to cause Hemorrhagic Cystitis Cytoxan, Ifosfamide
18. 5 Nephrotoxic Chemotherapy Drugs MTX, Ifosfamide, Cytoxan,
Carboplatin, Cisplatin
19. 5 Chemotherapy Drugs to Cause Hypersensitivity Asparaginase, Car-
boplatin, Etoposide,
Bleomycin, Pailitaxel
20. 2 Biotherapy Drugs that Cause Neurotoxicity Tisagenlecleucel, Blinatu-
momab
2/6
