NAPSRx CNPR Exam Study Guide – Revised 18th Edition (NEW Updated Version 2025/2026) Comprehensive Practice Questions with Correct Answers and Detailed Explanations for Pharmaceutical Sales Certification Candidates

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NAPSRx CNPR Exam (Revised 18th Edition) (NEW UPDATED VERSION)
LATEST ACTUAL EXAM QUESTIONS AND CORRECT ANSWERS (VERIFIED
QUESTIONS AND ANSWERS) -GUARANTEED PASS A+ UPDATED THIS YEAR
what does a STAT order mean? - CORRECT ANSWER a drug needed immediately and
given only once


QUESTION :what information does the overdosage section of the labeling provide? -
CORRECT ANSWER signs, symptoms and treatment of acute overdoses



QUESTION :types of drug-drug interactions: - CORRECT ANSWER duplication,
opposition (antagonism) and alteration (p.51)



QUESTION :tolerance vs resistance - CORRECT ANSWER tolerance is the diminished
response to a drug; resistance is the cells ability to resist the effects of the drug on them.



QUESTION :abbreviated new drug application (ANDA) - CORRECT ANSWER the
process by which applicants must scientifically demonstrate to the FDA that their generic
product is bioequivalent to or performs in the same way as the innovator drug, no duplicate
testing (p. 75)



QUESTION :the Hatch-Waxman Act of 1984 - CORRECT ANSWER -A.K.A. Drug Price
Competition and Patent Restoration Act
-made it easier to bring generic drugs to the market by requiring the FDA to only look at
bioavailability studies in order to approve an ANDA.
-gave protection to the research based manufacturers by providing a 30-month automatic
cooling off period once an ANDA is challenged for patent infringement (p. 75)



QUESTION :four basic transport mechanisms - CORRECT ANSWER passive diffusion,
facilitated diffusion, active transport, and pinocytosis (p. 95)



QUESTION :potency vs efficacy - CORRECT ANSWER potency: amount of drug
necessary to produce desired effect
efficacy: magnitude of maximal response that can be received from a drug



2026 2027 GRADED A+

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*efficacy is almost always more important that potency* (p. 106)



QUESTION :the four phases of clinical trials - CORRECT ANSWER phases I-IV (P. 124-
126)



QUESTION :Key Parts Of A Clinical Paper (5) - CORRECT ANSWER Abstract,
Introduction, methods, results, discussion/conclusions (p. 128-129)



QUESTION :reliability vs validity - CORRECT ANSWER reliability = consistency and
validity = accuracy
(p. 138; 143)



QUESTION :sampling error vs selection bias - CORRECT ANSWER sampling error is
unbiased and is randomly chosen from the population.
selection bias is when the sample was specifically chosen based on particular characteristics
(p.142-143)



QUESTION :independent vs dependent variable - CORRECT ANSWER An independent
variable is the one that influences the variation. A dependent variable is the variable being
tested and measured in a scientific experiment (the result of applying the independent variable).



QUESTION :Drug Utilization Review (DUR) programs - CORRECT ANSWER -involve
retrospective monitoring of physicians' prescribing patterns
-more than 90% of HMOs require DURs
-nowadays mostly monitors cost savings (p. 181)



QUESTION :opportunity cost - CORRECT ANSWER based on the premise that all
resources are scarce, and therefore every time we choose to use a resource it reduces the
possibility of it being used in another way.



QUESTION :what type of DTC advertising is the only legal form in Europe? - CORRECT
ANSWER Disease-state or unbranded ads (provides public information on a disease, not a
drug)



2026 2027 GRADED A+