2535- PATHOPHYSIOLOGY & PHARM INTEGRATION I YORK UNIVERSITY

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2535- PATHOPHYSIOLOGY & PHARM INTEGRATION I YORK UNIVERSITY

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2025/2026

Institution NURS 2535

Course NURS 2535

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2535- PATHOPHYSIOLOGY & PHARM INTEGRATION I YORK UNIVERSITY

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2535- PATHOPHYSIOLOGY & PHARM
INTEGRATION I YORK UNIVERSITY

What0is0a0drug?0-
0ans✔Any0chemical0that0affects0the0physiological0processes0of0a0living0organism

Pharmacology0-0ans✔The0broadest0term0for0the0study0or0science0of0drugs.

What030names0can0a0drug0have?0-0ans✔1.Chemical0name

2.Generic0name0(nonproprietary,0official0name)

3.Trade0name0(proprietary0name)

Chemical0name0-
0ans✔•Describes0the0drug's0chemical0composition0and0molecular0structure

•Generic0name0(nonproprietary,0official0name)0-
0ans✔•Name0given0to0a0drug0approved0by0Health0Canada

•Trade0name0(proprietary0name)0-
0ans✔•The0drug0has0a0registered0trademark;0use0of0the0name0is0restricted0by0the0dru
g's0patent0owner0(usually0the0manufacturer).

what020methods0are0drugs0classified0by?0-0ans✔structure0and0therapeutic0use

what0are0the030basic0phases0of0pharmacology0-0ans✔pharmaceutics
pharmacokinetics0and
pharmacodynamics

what0is0pharmaceutics?0-
0ans✔The0study0of0how0various0drug0forms0influence0the0way0in0which0the0drug0affect
s0the0body

What0is0dissolving0-0ans✔Ødissolving0of0solid0dosage0forms0and0their0absorption

What0is0pharmacokinetics0-0ans✔The0study0of0what0the0body0does0to0the0drug

,From0the0time0drug0is0put0into0the0body0until0the0parent0drug0and0metabolites0have0lef
t0the0body

what0are0the040phases0of0pharmacokinetics0-0ans✔ØAbsorption
ØDistribution
ØMetabolism
ØExcretion

what0factors0does0are0included0within0absoprtion0-0ans✔Bioavalibility0and0first-
past0effect

What0routes0are0in0the0body0-0ans✔•Enteral0route
•Sublingual0and0buccal0routes
•Topical0route
•Transdermal0route
•Inhalation0route

what0parenteral0routes0are0there0-0ans✔Intradermally
subcutaneously
Intravenously
Intramuscularly
Intrathecally
intra-articularly
intra-arterially

What0is0the0first0pass0effect?0-
0ans✔After0oral0administration,0many0drugs0are0absorbed0intact0from0the0small0intesti
ne0and0transported0first0via0the0portal0system0to0the0liver,0where0they0undergo0extensi
ve0metabolism,0therefore0usually0decreasing0the0bioavailability0of0certain0oral0medicati
ons.

what0is0the0entreal0route?0-
0ans✔The0drug0is0absorbed0into0the0systemic0circulation0through0the0mucosa0of0the0st
omach,0small0intestine,0or0large0intestine
ØOral
ØSublingual
ØBuccal
ØRectal0(can0also0be0topical)

what0are0topical0routes?0-0ans✔Skin0(including0transdermal0patches)
Eyes
Ears
Nose
Lungs0(inhalation)
Rectum
Vagina

, What0is0a0Peak0Level0-0ans✔highest0blood0level0of0a0drug

What0is0a0trough0level0-0ans✔lowest0blood0level0of0a0drug

What0is0toxicity0-
0ans✔occurs0if0the0peak0blood0level0of0the0drug0is0too0high,0which0is0why0we0use0ther
apeutic0drug0monitoring

what0is0a0loading0dose0-
0ans✔Øa0higher0amount0of0the0drug0is0given,0often0only0once0or0twice0to0increase0the
0drug0level0in0the0bloodstream0with0a0level0sufficient0to0induce0a0therapeutic0response

What0is0a0maintenance0dose0-
0ans✔Øintermittent0doses0of0the0drug0are0given0to0maintain0a0therapeutic0level0of0the0
drug0in0the0bloodstream

what0mechanims0of0actions0do0drugs0go0through0-0ans✔ØReceptor0interactions
ØEnzyme0interactions

What0is0Pharmacotherapeutics0-
0ans✔The0clinical0use0of0drugs0to0prevent0and0treat0diseases
Desired0therapeutic0outcomes0is0patient-
specific,0established0in0collaboration0with0the0patient.
Outcome0goals0need0to0be0realistic.

what0types0of0therapy0are0there0-0ans✔ØAcute
ØMaintenance
ØSupplemental0(or0replacement)
ØPalliative
ØSupportive
ØProphylactic
ØEmpirical

What0is0tolerance0-0ans✔decreasing0response0to0repeated0drug0doses

What0is0Dependence0-0ans✔physiological0or0psychological0need0for0a0drug

What0is0physical0dependence0-
0ans✔Øphysiological0need0for0a0drug0to0avoid0physical0withdrawal0symptoms

what0is0psychological0dependence0-0ans✔Øobsessive0desire0for0a0drug

What0is0the0Nursing0process0-0ans✔•A0research-
based0organizational0framework0for0professional0nursing0practice

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Uploaded on: December 15, 2025
Number of pages: 28
Written in: 2025/2026
Type: Exam (elaborations)
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