Hematology Exam 3 Chapter 8 and 9 Turgeon Book QUESTIONS WITH ANSWERS

Hematology Exam 3 Chapter 8 and 9 |\ |\ |\ |\ |\ |\ |\




Turgeon Book QUESTIONS WITH |\ |\ |\ |\




ANSWERS

Describe leukopoiesis and the steps leading from
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immature forms to maturation - CORRECT ANSWERS
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✔✔Pluripotent stem cell - CFU-GEMM |\ |\ |\ |\




Myeloblast
Promyelocyte - nonspecific primary granuals |\ |\ |\ |\




Myelocyte - specific secondary granuals
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Metamyelocyte
Band
Segmented neutrophil |\




80% - CORRECT ANSWERS ✔✔amount of t-lymphs
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plasma cell - CORRECT ANSWERS ✔✔dark blue with light
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stain, eccentric nucleus and hof containing golgi
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myeloblast N:C ratio - CORRECT ANSWERS ✔✔4:1
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,metamyelocyte - CORRECT ANSWERS ✔✔kidney shaped |\ |\ |\ |\ |\ |\



nucleus, clumped chromatin, and small pink, secondary
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granules with few dark primary granules
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What cytokine chemical acts on promyelocytes to make it
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form eosinophils, basophils, neutrophils? - CORRECT
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ANSWERS ✔✔Interlukin (IL-3) |\ |\




Name four morphologic features that are helpful in
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differentiation the cells of the granulocytic series - |\ |\ |\ |\ |\ |\ |\ |\



CORRECT ANSWERS ✔✔Nucleus size and shape |\ |\ |\ |\ |\




Cytoplasm color |\




Presence of granules |\ |\




Color of granules
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Overall size |\




Presence of nucleoli |\ |\




N:C ratio
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Describe the features that differentiate the granules of
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the neutrophilic, eosinophilic, and basophilic cell lines -
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CORRECT ANSWERS ✔✔Neutrophil - fine specific
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secondary granuals, pale lilac with blue shading
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Eosinophil- large specific secondary granuals, red |\ |\ |\ |\ |\




Basophil- large specific secondary granuals, purple
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, Distinguish between the margination and circulating pools |\ |\ |\ |\ |\ |\



of leukocytes - CORRECT ANSWERS ✔✔Marginating pool -
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located along the vessel wall with cells ready to migrate
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to the site of injury or infection
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Circulating pool - those cells actually present in the blood
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stream


Primary lymph tissue - CORRECT ANSWERS ✔✔Thymus,
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bone marrow |\




Secondary lymph tissue - CORRECT ANSWERS ✔✔lymph |\ |\ |\ |\ |\ |\ |\



nodes, tonsils, spleen, Peyer's patches
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Cluster of Differentiation (CD) - CORRECT ANSWERS
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✔✔Surface antigen markers determined biochemically or |\ |\ |\ |\ |\ |\



through flow cytometry |\ |\




Each cell line has specific surface antigens that identify it
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Designated by a number - CD2, CD3, CD4, etc. |\ |\ |\ |\ |\ |\ |\ |\




Become very important when diagnosing a leukemia
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Very important for treatment plan and outcome
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What happens when a B-lymph is stimulated? - CORRECT
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ANSWERS ✔✔Turns into a plasma cell and produces |\ |\ |\ |\ |\ |\ |\ |\



immunoglobins aka antibodies |\ |\