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AGACNP AACN Boards Questions and Answers Updated 2026

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AGACNP AACN Boards Questions and Answers Updated 2026

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December 12, 2025
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AGACNP AACN Boards Questions and
Answers Updated 2026


3 steps of pain management - Answer1. aspirin, tylenol, NSAIDs

2. codeine, hydrocodone, oxycodone, tramadol (only with NSAIDS)

3. morphine, hydromorphone, methadone, fentanyl



Breakthrough cancer pain management - Answerfentanyl



Metastatic bone pain management - Answerbisphosphonates



Tension headache symptoms & management - Answersymptoms - tight, back of head/neck

management - OTC analgesics and rest



Migraine headache types and treatments - Answerclassic - WITH aura

common - WITHOUT aura

treatment - sumatriptan and analgesics



Cluster headache symptoms and management - Answersymptoms - occur at night, ipsilateral
congestion, rhinorrhea, and eye redness



Albumin levels <3.5 - Answerprotein malnutrition



Albumin <2.7 - AnswerEdema



Complications of enteral nutrition - Answeraspiration, refeeding, dehydration



Complications of parenteral nutrition - Answerpneumothorax, hemothorax

,Urine sodium >20 - Answerrenal salt wasting (kidney is the problem)



Urine sodium <10 - Answerkidney isn't the problem



isotonic hyponatremia serum osmolality and causes - Answerserum osmolality - 284-295

causes - extreme hyperlipidemia or nhyperproteinemia



hypotonic hyponatremia serum osmolality and types - Answerserum osmolality <280

hypovolemic w/ sodium <10

hypovolemic w/ sodium >20

hypervolemic



hypovolemic w/ urine sodium <10 causes - Answerdehydration, diuresis, vomiting



hypovolemic w/ urine sodium >20 - Answerdiuretics, ACE, mineralocorticoid deficiency



hypervolemic hypotonic hyponatremia - Answeredema, CHF, liver disease, renal failure

must restrict fluids



hypertonic hyponatremia serum osmolality and causes - Answerserum osmolality >290

causes - HHS



hypokalemia causes, signs/symptoms, treatment - Answercauses - diuretics, GI losses, renal loss,
alkalosis

signs/symptoms - weakness, fatigue, cramps, broad T waves, u waves

treatment - oral replacement if >2.5, 40mEq/L/hr IV if severe



hyperkalemia causes, signs/symptoms, treatment - Answercauses - renal failure, drugs,
hypoaldosteronism

signs/symptoms - weakness, flaccid paralysis, abdominal distension, diarrhea, peaked T waves

treatment - ion resin exchange (kayexalate), insulin, D5W

, hypocalcemia causes, signs/symptoms, treatment - Answercauses - pancreatitis, renal failure,
trauma, massive transfusions

symptoms - increased DTRs, cramps, convulsions, prolonged QT, Chvostek's and Trousseau's sign

treatment - check for alkalosis, IV calcium gluconate if acute, oral supplements if chronic



hypercalcemia causes, signs/symptoms, treatment - Answercauses - vitamin D intoxication,
immobilization, thiazide diuretics

symptoms - fatigue, muscle weakness, constipation, coma, death

treatment - calcitonin if renal/card involvement, NS, loop diuretics, dialysis if severe



respiratory acidosis causes, signs/symptoms, treatment - Answercauses - hypoventilation (pH<7.35,
pCO2>45)

symptoms - somnolence, confusion, coma, myoclonus with asterixis

treatment - narcan if unknown cause, increased ventilator rate



respiratory alkalosis causes, signs/symptoms, treatment - Answercauses - hyperventilation (pH>7.45,
pCO2<35)

symptoms - lightheadedness, tingling, tetany if severe

treatment - paper bag breathing, decreased ventilator rate



metabolic acidosis types, causes, treatment - Answertypes:

increased anion gap - DKA, alcoholic ketoacidosis, lactic acidosis

normal anion gap - diarrhea, ileostomy, renal tubular acidosis, DKA recovery



treat with fluids



metabolic alkalosis causes, signs/symptoms, treatment - Answercauses - saline responsive, NG
suction, vomiting, diuretics

treatment - d/c diuretics, give NaCl and KCl, H2 blockers if GI loss



Gram positive bacteria - Answerstreptococci, staphylococcus, enterococci, bacilli



Gram negative bacteria - AnswerE. coli, klebsiella, pseudomonas, acinetobacter, enterobacter
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