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HESI Comprehensive Exam A (2025–2026 Edition) – Fully Verified Questions, Answers & Rationales with High-Score Nursing Review Pack

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This resource provides a fully updated 2025–2026 edition of the HESI Comprehensive Exam A, featuring 100% verified questions, accurate answers, and detailed rationales. It is designed to help nursing students master key concepts across all major exam domains, including clinical judgment, pharmacology, patient care, and critical thinking. The review pack offers high-yield content aligned with the latest HESI standards, ensuring targeted studying and strengthened exam readiness. Ideal for students aiming to boost their confidence and achieve a top score on the HESI Comprehensive Exam A.

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HESI COMPREHENSIVE EXAM A (2025_2026 EDITION) |
100% VERIFIED QUESTIONS, ANSWERS & RATIONALES |
HIGH-SCORE NURSING REVIEW PACK
1. Enalapril maleate is prescribed for a hospitalized client. Which assessment does the nurse
perform as a priority before administering the medication?

A. Checking the client's blood pressure

B. Checking the client's peripheral pulses

C. Checking the most recent potassium level

D. Checking the client's intake-and-output record for the last 24 hours - CORRECT ANSWER-A.
Checking the client's blood pressure



2. A client is scheduled to undergo an upper gastrointestinal (GI) series, and the nurse provides
instructions to the client about the test. Which statement by the client indicates a need for
further instruction?

A. "The test will take about 30 minutes."

B. "I need to fast for 8 hours before test."

C. "I need to drink citrate of magnesia the night before the test and give myself a Fleet enema
on the morning of the test."

D. "I need to take a laxative after the test is completed, because the liquid that I'll have to drink
for the test can be constipating." - CORRECT ANSWER-C. "I need to drink citrate of magnesia the
night before the test and give myself a Fleet enema on the morning of the test."



3. A nurse on the evening shift checks a health care provider's prescriptions and notes that the
dose of a prescribed medication is higher than the normal dose. The nurse calls the health care
provider's answering service and is told that the health care provider is off for the night and will
be available in the morning. The nurse should:

A. Call the nursing supervisor

B. Ask the answering service to contact the on-call health care provider

,C. Withhold the medication until the health care provider can be reached in the morning

D. Administer the medication but consult the health care provider when he becomes available -
CORRECT ANSWER-B. Ask the answering service to contact the on-call health care provider



4. An emergency department (ED) nurse is monitoring a client with suspected acute myocardial
infarction (MI) who is awaiting transfer to the coronary intensive care unit. The nurse notes the
sudden onset of premature ventricular contractions (PVCs) on the monitor, checks the client's
carotid pulse, and determines that the PVCs are not resulting in perfusion. The appropriate
action by the nurse is:

A. Documenting the findings

B. Asking the ED health care provider to check the client

C. Continuing to monitor the client's cardiac status

D. Informing the client that PVCs are expected after an MI - CORRECT ANSWER-B. Asking the ED
health care provider to check the client



5. NPO status is imposed 8 hours before the procedure on a client scheduled to undergo
electroconvulsive therapy (ECT) at 1 p.m. On the morning of the procedure, the nurse checks
the client's record and notes that the client routinely takes an oral antihypertensive medication
each morning. The nurse should:

A. Administer the antihypertensive with a small sip of water

B. Withhold the antihypertensive and administer it at bedtime

C. Administer the medication by way of the intravenous (IV) route

D. Hold the antihypertensive and resume its administration on the day after the ECT - CORRECT
ANSWER-A. Administer the antihypertensive with a small sip of water



6. A client who recently underwent coronary artery bypass graft surgery comes to the health
care provider's office for a follow-up visit. On assessment, the client tells the nurse that he is
feeling depressed. Which response by the nurse is therapeutic?

A. "Tell me more about what you're feeling."

B. "That's a normal response after this type of surgery."

,C. "It will take time, but, I promise you, you will get over this depression."

D. "Every client who has this surgery feels the same way for about a month." - CORRECT
ANSWER-A. "Tell me more about what you're feeling."



7. A client in labor eẋperiences spontaneous rupture of the membranes. The nurse immediately
counts the fetal heart rate (FHR) for 1 full minute and then checks the amniotic fluid. The nurse
notes that the fluid is yellow and has a strong odor. Which action should be the nurse's priority?

A. Contacting the health care provider

B. Documenting the findings

C. Checking the fluid for protein

D. Continuing to monitor the client and the FHR - CORRECT ANSWER-A. Contacting the health
care provider



8. A nurse has assisted a health care provider in inserting a central venous access device into a
client with a diagnosis of severe malnutrition who will be receiving parenteral nutrition (PN).
After insertion of the catheter, the nurse immediately plans to:

A. Call the radiography department to obtain a chest ẋ-ray

B. Check the client's blood glucose level to serve as a baseline measurement

C. Hang the prescribed bag of PN and start the infusion at the prescribed rate

D. Infuse normal saline solution through the catheter at a rate of 100 mL/hr to maintain patency
- CORRECT ANSWER-A. Call the radiography department to obtain a chest ẋ-ray



9. A rape victim being treated in the emergency department says to the nurse, "I'm really
worried that I've got HIV now." What is the appropriate response by the nurse?

A. "HIV is rarely an issue in rape victims."

B. "Every rape victim is concerned about HIV."

C. "You're more likely to get pregnant than to contract HIV."

, D. "Let's talk about the information that you need to determine your risk of contracting HIV." -
CORRECT ANSWER-D. "Let's talk about the information that you need to determine your risk of
contracting HIV."



10. A client is taking prescribed ibuprofen , 300 mg orally four times daily, to relieve joint pain
resulting from rheumatoid arthritis. The client tells the nurse that the medication is causing
nausea and indigestion. The nurse should tell the client to:

A. Contact the health care provider

B. Stop taking the medication

C. Take the medication with food

D. Take the medication twice a day instead of four times - CORRECT ANSWER-C. Take the
medication with food



11. A client's oral intake of liquids includes 120 mL on the night shift, 800 mL on the day shift,
and 650 mL on the evening shift. The client is receiving an intravenous (IV) antibiotic every 12
hours, diluted in 50 mL of normal saline solution. The nurse empties 700 mL of urine from the
client's Foley catheter at the end of the day shift. Thereafter, 500 mL of urine is emptied at the
end of the evening shift and 325 mL at the end of the night shift. Nasogastric tube drainage
totals 155 mL for the 24-hour period, and the total drainage from the Jackson-Pratt device is
175 mL. What is the client's total intake during the 24-hour period? Type your answer in the
space provided. ________mL - CORRECT ANSWER-1670 mL

Rationale: The client's 24-hour total oral intake is 1570 mL, and the IV intake totals 100 mL (50
mL of normal saline solution every 12 hours). Therefore the 24-hour intake total is 1670 mL.



12. Lorazepam 1 mg by way of intravenous (IV) injection (IV push) is prescribed for a client for
the management of anẋiety. The nurse prepares the medication as prescribed and administers
the medication over a period of:

A. 3 minutes

B. 10 seconds

C. 15 seconds

D. 30 minutes - CORRECT ANSWER-A. 3 minutes

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