AAB MT Hematology EXAM Questions with
100% Correct Answers | Verified | Latest Update
2026/2027 | Graded A+.
What is hemoglobin composed of? - ✔✔4 heme, 4 iron, 4 globins
What disorder does a defect in heme synthesis lead to? - ✔✔Porphyria
What is methemoglobin? - ✔✔Methemoglobin is a form of hemoglobin
that contains ferric [Fe3+] iron and has a decreased ability to bind
oxygen. However, the ferric iron has an increased affinity for bound
oxygen. When methemoglobin concentration is elevated in red blood
cells, tissue hypoxia can occur.
,What is the function of the enzyme methemoglobin-cytochrome C
reductase in a red blood cell? - ✔✔To keep iron in the ferrous state
What product is formed when ferrous iron of hemoglobin is oxidized to
the ferric state? - ✔✔Methemoglobin
Porphyria - ✔✔Deficiency in the enzymes of the porphyrin pathway
leads to insufficient production of heme. The principal problem in these
deficiencies is the accumulation of porphyrins, the heme precursors,
which are toxic to tissue in high concentrations.
What is carboxyhemoglobin? - ✔✔A stable complex of carbon
monoxide and hemoglobin that forms in RBCs when carbon monoxide
is inhaled or produced in normal metabolism. Large quantities of it
hinder delivery of O2 to the body. Tobacco smoking (through carbon
,monoxide inhalation) raises the blood levels of COHb by a factor of
several times from its normal concentrations.
Which hemoglobin has a 200 times greater binding capacity for the
hemoglobin molecule than oxygen? - ✔✔Carboxyhemoglobin
Which of the following hemoglobins is NOT normally present in a
normal adult? -
✔✔Hb-S
Which embryonic hemoglobin is normally found in newborns? - ✔✔Hb-
F
What is the most abundant hemoglobin in a newborn? - ✔✔Hb-F
, What is the molecular structure of Hemoglobin S? - ✔✔Valine replaces
glutamic acid in the 6th position of the beta chain
Which of the following hemoglobins is insoluble under lowered oxygen
tension? -
✔✔Hb-S
What laboratory test is used to confirm the specific diagnosis of sickle
cell anemia? - ✔✔Hemoglobin electrophoresis
Which hemoglobin derivative causes irreversible changes in RBCs? -
✔✔Sulfhemoglobin -- makes blood incapable of carrying oxygen.
In the solubility test for hemoglobin S, what is the reagent responsible
for the reduction of the hemoglobin molecule? - ✔✔Sodium dithionite
100% Correct Answers | Verified | Latest Update
2026/2027 | Graded A+.
What is hemoglobin composed of? - ✔✔4 heme, 4 iron, 4 globins
What disorder does a defect in heme synthesis lead to? - ✔✔Porphyria
What is methemoglobin? - ✔✔Methemoglobin is a form of hemoglobin
that contains ferric [Fe3+] iron and has a decreased ability to bind
oxygen. However, the ferric iron has an increased affinity for bound
oxygen. When methemoglobin concentration is elevated in red blood
cells, tissue hypoxia can occur.
,What is the function of the enzyme methemoglobin-cytochrome C
reductase in a red blood cell? - ✔✔To keep iron in the ferrous state
What product is formed when ferrous iron of hemoglobin is oxidized to
the ferric state? - ✔✔Methemoglobin
Porphyria - ✔✔Deficiency in the enzymes of the porphyrin pathway
leads to insufficient production of heme. The principal problem in these
deficiencies is the accumulation of porphyrins, the heme precursors,
which are toxic to tissue in high concentrations.
What is carboxyhemoglobin? - ✔✔A stable complex of carbon
monoxide and hemoglobin that forms in RBCs when carbon monoxide
is inhaled or produced in normal metabolism. Large quantities of it
hinder delivery of O2 to the body. Tobacco smoking (through carbon
,monoxide inhalation) raises the blood levels of COHb by a factor of
several times from its normal concentrations.
Which hemoglobin has a 200 times greater binding capacity for the
hemoglobin molecule than oxygen? - ✔✔Carboxyhemoglobin
Which of the following hemoglobins is NOT normally present in a
normal adult? -
✔✔Hb-S
Which embryonic hemoglobin is normally found in newborns? - ✔✔Hb-
F
What is the most abundant hemoglobin in a newborn? - ✔✔Hb-F
, What is the molecular structure of Hemoglobin S? - ✔✔Valine replaces
glutamic acid in the 6th position of the beta chain
Which of the following hemoglobins is insoluble under lowered oxygen
tension? -
✔✔Hb-S
What laboratory test is used to confirm the specific diagnosis of sickle
cell anemia? - ✔✔Hemoglobin electrophoresis
Which hemoglobin derivative causes irreversible changes in RBCs? -
✔✔Sulfhemoglobin -- makes blood incapable of carrying oxygen.
In the solubility test for hemoglobin S, what is the reagent responsible
for the reduction of the hemoglobin molecule? - ✔✔Sodium dithionite
