MCB 2050 RNA modification Questions With Complete
Solutions
1-3 tra splice transcript
Functional Slx protein acts on the tra pre-mRNA transcript to
produce the _____________ .
1) tra
2) sxl
The functional Sxl protein acts on which of the following pre-
mRNA transcripts to regulate sex determination in Drosphila
embryos? Select all that apply. (there are 2)
miRNA
The RNA molecule that in involved in post-transcriptional
regulation through imperfect base paring with mRNA is:
i) Repress; ii) Activate
The functional sxl protein in drosphila functions to i)
_____(1)______ splicing, while the tra works in cooperation
with SR proteins to ii) ____(2)______ splicing.
Exon 3 is retained, contains stop codon, non-functional protein
produced
Explain how the absence of the Sxl protein in male embryos
regulates the processing of the Sxl mRNA
exon 3 contains a stop codon, so this produces a non functional
protein
, What is the consequence of this splicing event in the Sxl mRNA
for the function of the Sxl protein (follow up from last question)
blocks the splicing of the 2nd exon of the tra mRNA, leading to
a 1,3 tra splice transcript, produces functional protein
Explain how the presence of the Sxl protein in female embryos
regulates the expression of the Tra protein
d) Efficiency of translation
b) mRNA stability
The length of the polyA tail regulates which of the following
processes
a) Ribosome docking
b) mRNA stability
c) Efficiency of transcription
d) efficiency of translation
b) miRNAs bind perfectly to their target RNA
Which of the following statements about miRNA is
INCORRECT?
a) miRNAs usually bind to the 3'-UTR of the target RNA
b) miRNAs bind perfectly to their target RNA
c) miRNAs inhibit the translation of the target mRNAs
d) miRNAs are generated from larger double stranded RNAs
e) all of the above answers are correct
d) The RNA will be degraded by the nonsense-decay
mechanism
Solutions
1-3 tra splice transcript
Functional Slx protein acts on the tra pre-mRNA transcript to
produce the _____________ .
1) tra
2) sxl
The functional Sxl protein acts on which of the following pre-
mRNA transcripts to regulate sex determination in Drosphila
embryos? Select all that apply. (there are 2)
miRNA
The RNA molecule that in involved in post-transcriptional
regulation through imperfect base paring with mRNA is:
i) Repress; ii) Activate
The functional sxl protein in drosphila functions to i)
_____(1)______ splicing, while the tra works in cooperation
with SR proteins to ii) ____(2)______ splicing.
Exon 3 is retained, contains stop codon, non-functional protein
produced
Explain how the absence of the Sxl protein in male embryos
regulates the processing of the Sxl mRNA
exon 3 contains a stop codon, so this produces a non functional
protein
, What is the consequence of this splicing event in the Sxl mRNA
for the function of the Sxl protein (follow up from last question)
blocks the splicing of the 2nd exon of the tra mRNA, leading to
a 1,3 tra splice transcript, produces functional protein
Explain how the presence of the Sxl protein in female embryos
regulates the expression of the Tra protein
d) Efficiency of translation
b) mRNA stability
The length of the polyA tail regulates which of the following
processes
a) Ribosome docking
b) mRNA stability
c) Efficiency of transcription
d) efficiency of translation
b) miRNAs bind perfectly to their target RNA
Which of the following statements about miRNA is
INCORRECT?
a) miRNAs usually bind to the 3'-UTR of the target RNA
b) miRNAs bind perfectly to their target RNA
c) miRNAs inhibit the translation of the target mRNAs
d) miRNAs are generated from larger double stranded RNAs
e) all of the above answers are correct
d) The RNA will be degraded by the nonsense-decay
mechanism
