ASCP Blood Bank Practice Questions |\ |\ |\ |\ |\
WITH CORRECT ANSWERS |\ |\
Results of a serum sample tested against a panel of reagent red
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
cells gives presumptive evidence of an alloantibody directed
|\ |\ |\ |\ |\ |\ |\ |\
against a high incidence antigen. Further investigation to confirm
|\ |\ |\ |\ |\ |\ |\ |\
the specificity should include which of the following?
|\ |\ |\ |\ |\ |\ |\ |\
A.serum testing against red cells from random donors
|\ |\ |\ |\ |\ |\ |\
B.serum testing against red cells known to lack high incidence
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
antigens
C.serum testing against enzyme treated autologous red cells
|\ |\ |\ |\ |\ |\ |\
D.testing of an eluate prepared from the patient's red cells
|\ |\ |\ |\ |\ |\ |\ |\ |\
B. serum testing against red cells known to lack high incidence
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
antigens
Fetal neonatal alloimmune thrombocytopenia (FNAIT) is caused
|\ |\ |\ |\ |\ |\ |\
by which of the following maternal antibodies?
|\ |\ |\ |\ |\ |\
,A.IgM alloantibodies against ABO antigens
|\ |\ |\ |\
B.IgG alloantibodies against HLA antigens
|\ |\ |\ |\
C.IgM alloantibodies against glycoprotein V (GPV) antigens
|\ |\ |\ |\ |\ |\
D.IgG alloantibodies against HPA antigens
|\ |\ |\ |\
D. IgG alloantibodies against HPA antigens
|\ |\ |\ |\ |\
FNAIT is due to maternal IgG alloantibodies crossing the placenta
|\ |\ |\ |\ |\ |\ |\ |\ |\
and reacting with fetal platelet HPA antigens.
|\ |\ |\ |\ |\ |\ |\
The purpose of testing with anti-A,B is to detect:
|\ |\ |\ |\ |\ |\ |\ |\
A.anti-A1
B.anti-A2
C.subgroups of A |\ |\
D.subgroups of O |\ |\
,Subgroups of A |\ |\
Ax cells react more strongly with anti-A,B than with anti-A. If anti-
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
A is nonreactive, Ax cells may be detected with anti-A,B.
|\ |\ |\ |\ |\ |\ |\ |\ |\
What increment of platelets in the typical 70-kg human is
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
expected to result from each single unit of Platelets transfused to
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
a non-HLA-sensitized recipient?
|\ |\ |\
A.3,000 - 5,000/µL |\ |\
B.5,000 - 10,000/µL |\ |\
C.20,000 - 25,000/µL |\ |\
D.25,000 - 30,000/µL |\ |\
B.5,000 - 10,000/µL |\ |\
One unit of Platelets made from whole blood should cause the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
platelet count to increase from 5,000-10,000/µL.
|\ |\ |\ |\ |\
, All donor blood testing must include:
|\ |\ |\ |\ |\
A.complete Rh phenotyping |\ |\
B.anti-CMV testing |\
C.direct antiglobulin test
|\ |\
D.serological test for syphilis |\ |\ |\
D.serological test for syphilis |\ |\ |\
A sample gives the following results:
|\ |\ |\ |\ |\
Cells with Anti A: 3+ Anti B: 4+
|\ |\ |\ |\ |\ |\ |\
Serum with A1: 2+ and B: 0
|\ |\ |\ |\ |\ |\
Which lectin should be used first to resolve this discrepancy?
|\ |\ |\ |\ |\ |\ |\ |\ |\
A.Ulex europaeus|\
WITH CORRECT ANSWERS |\ |\
Results of a serum sample tested against a panel of reagent red
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
cells gives presumptive evidence of an alloantibody directed
|\ |\ |\ |\ |\ |\ |\ |\
against a high incidence antigen. Further investigation to confirm
|\ |\ |\ |\ |\ |\ |\ |\
the specificity should include which of the following?
|\ |\ |\ |\ |\ |\ |\ |\
A.serum testing against red cells from random donors
|\ |\ |\ |\ |\ |\ |\
B.serum testing against red cells known to lack high incidence
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
antigens
C.serum testing against enzyme treated autologous red cells
|\ |\ |\ |\ |\ |\ |\
D.testing of an eluate prepared from the patient's red cells
|\ |\ |\ |\ |\ |\ |\ |\ |\
B. serum testing against red cells known to lack high incidence
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
antigens
Fetal neonatal alloimmune thrombocytopenia (FNAIT) is caused
|\ |\ |\ |\ |\ |\ |\
by which of the following maternal antibodies?
|\ |\ |\ |\ |\ |\
,A.IgM alloantibodies against ABO antigens
|\ |\ |\ |\
B.IgG alloantibodies against HLA antigens
|\ |\ |\ |\
C.IgM alloantibodies against glycoprotein V (GPV) antigens
|\ |\ |\ |\ |\ |\
D.IgG alloantibodies against HPA antigens
|\ |\ |\ |\
D. IgG alloantibodies against HPA antigens
|\ |\ |\ |\ |\
FNAIT is due to maternal IgG alloantibodies crossing the placenta
|\ |\ |\ |\ |\ |\ |\ |\ |\
and reacting with fetal platelet HPA antigens.
|\ |\ |\ |\ |\ |\ |\
The purpose of testing with anti-A,B is to detect:
|\ |\ |\ |\ |\ |\ |\ |\
A.anti-A1
B.anti-A2
C.subgroups of A |\ |\
D.subgroups of O |\ |\
,Subgroups of A |\ |\
Ax cells react more strongly with anti-A,B than with anti-A. If anti-
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
A is nonreactive, Ax cells may be detected with anti-A,B.
|\ |\ |\ |\ |\ |\ |\ |\ |\
What increment of platelets in the typical 70-kg human is
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
expected to result from each single unit of Platelets transfused to
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
a non-HLA-sensitized recipient?
|\ |\ |\
A.3,000 - 5,000/µL |\ |\
B.5,000 - 10,000/µL |\ |\
C.20,000 - 25,000/µL |\ |\
D.25,000 - 30,000/µL |\ |\
B.5,000 - 10,000/µL |\ |\
One unit of Platelets made from whole blood should cause the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
platelet count to increase from 5,000-10,000/µL.
|\ |\ |\ |\ |\
, All donor blood testing must include:
|\ |\ |\ |\ |\
A.complete Rh phenotyping |\ |\
B.anti-CMV testing |\
C.direct antiglobulin test
|\ |\
D.serological test for syphilis |\ |\ |\
D.serological test for syphilis |\ |\ |\
A sample gives the following results:
|\ |\ |\ |\ |\
Cells with Anti A: 3+ Anti B: 4+
|\ |\ |\ |\ |\ |\ |\
Serum with A1: 2+ and B: 0
|\ |\ |\ |\ |\ |\
Which lectin should be used first to resolve this discrepancy?
|\ |\ |\ |\ |\ |\ |\ |\ |\
A.Ulex europaeus|\
