PHARMACOLOGY HESI
PRACTICE questions and answers
2025\2026 A+ Grade
A client is scheduled for a spiral computed tomography (CT) with contrast to evaluate for pulmonary
embolism. Which information in the client's history requires follow-up by the nurse?
- correct answer Takes metformin hydrochloride for type 2 diabetes mellitus
A client recently diagnosed with multiple sclerosis who self administers beta-1a interferon reports
feeling depressed. Which action should the nurse implement?
- correct answer Notify the healthcare provider of findings immediately.
Before administering the initial dose of sumatriptan succinate to a client with migraine headache. It is
most important to determine if the client's history includes which protein?
- correct answer Coronary artery disease
A client receives a prescription of ciprofloxacin 400 mg intravenously (IV) every 12 hours, which is to be
infused over an hour. The IV bag contains ciprofloxacin 400 mg in dextrose 5% water (D,W) 200 mL. How
many mL/hr should the nurse program the infusion pump to deliver? (Enter numerical value only.)
- correct answer
Before administering a laxative to a bedfast client, it is most important for the nurse to perform which
assessment?
- correct answer Determine the frequency and consistently of bowel movements.
Hormone replacement therapy with levothyroxine sodium is prescribed for a client with
hypothyroidism. The nurse should instruct the client to report which symptom because it indicates that
the client is taking too much of the hormonal agent, levothyroxine sodium?
- correct answer Restlessness
, A male client reports to the nurse that he is experiencing gastrointestinal distress from high dose of
corticosteroid and planning to stop taking the medication. In response the client's statement, which
nursing action is most important for the nurse to implement?
- correct answer Advise the client that the medication should be stopped gradually rather than abruptly.
A client is receiving pilocarpine hydrochloride ophthalmic drops for glaucoma. The client calls the clinic
nurse and reports difficulty seeing at night. Which explanation should the nurse provide?
- correct answer The eye drops slow pupil response to accommodate darkness.
A client is receiving rifampin and antitubercular medication. Which statement by this client should
prompt the nurse to notify the healthcare provider of potential problem?
- correct answer Complains of persistent tinnitus.
Which action should the nurse implement to assess the effectiveness of the calcium channel blocker
amlodipine?
- correct answer Measure the client's blood pressure.
A male client has been receiving the antibiotic gentamicin sulfate, IV piggyback every 12 hours for
several days. Which observation by the nurse indicates that the client may be experiencing an adverse
effect of gentamicin?
- correct answer Hearing has decreased.
An older adult client with restless legs syndrome begins taking melatonin at bedtime. When evaluating
effectiveness of the herb, which client assessment should the nurse to complete?
- correct answer Determine sleep patterns
The nurse prepares to administer a scheduled dose of labetaol by mouth to a client with hypertension.
The client's vital signs are temperature 99 F (37.2 C) heart rate 48 beats/minute respirations 16
breaths/minute, and blood pressure 150/90 mmHg. Which action should the nurse take?
- correct answer Withhold the scheduled dose and notify the healthcare provider
To evaluate the effectiveness of a client's prescription of rosuvastatin, which action should the nurse
implement?
- correct answer Evaluate the client's serum cholesterol level results.
PRACTICE questions and answers
2025\2026 A+ Grade
A client is scheduled for a spiral computed tomography (CT) with contrast to evaluate for pulmonary
embolism. Which information in the client's history requires follow-up by the nurse?
- correct answer Takes metformin hydrochloride for type 2 diabetes mellitus
A client recently diagnosed with multiple sclerosis who self administers beta-1a interferon reports
feeling depressed. Which action should the nurse implement?
- correct answer Notify the healthcare provider of findings immediately.
Before administering the initial dose of sumatriptan succinate to a client with migraine headache. It is
most important to determine if the client's history includes which protein?
- correct answer Coronary artery disease
A client receives a prescription of ciprofloxacin 400 mg intravenously (IV) every 12 hours, which is to be
infused over an hour. The IV bag contains ciprofloxacin 400 mg in dextrose 5% water (D,W) 200 mL. How
many mL/hr should the nurse program the infusion pump to deliver? (Enter numerical value only.)
- correct answer
Before administering a laxative to a bedfast client, it is most important for the nurse to perform which
assessment?
- correct answer Determine the frequency and consistently of bowel movements.
Hormone replacement therapy with levothyroxine sodium is prescribed for a client with
hypothyroidism. The nurse should instruct the client to report which symptom because it indicates that
the client is taking too much of the hormonal agent, levothyroxine sodium?
- correct answer Restlessness
, A male client reports to the nurse that he is experiencing gastrointestinal distress from high dose of
corticosteroid and planning to stop taking the medication. In response the client's statement, which
nursing action is most important for the nurse to implement?
- correct answer Advise the client that the medication should be stopped gradually rather than abruptly.
A client is receiving pilocarpine hydrochloride ophthalmic drops for glaucoma. The client calls the clinic
nurse and reports difficulty seeing at night. Which explanation should the nurse provide?
- correct answer The eye drops slow pupil response to accommodate darkness.
A client is receiving rifampin and antitubercular medication. Which statement by this client should
prompt the nurse to notify the healthcare provider of potential problem?
- correct answer Complains of persistent tinnitus.
Which action should the nurse implement to assess the effectiveness of the calcium channel blocker
amlodipine?
- correct answer Measure the client's blood pressure.
A male client has been receiving the antibiotic gentamicin sulfate, IV piggyback every 12 hours for
several days. Which observation by the nurse indicates that the client may be experiencing an adverse
effect of gentamicin?
- correct answer Hearing has decreased.
An older adult client with restless legs syndrome begins taking melatonin at bedtime. When evaluating
effectiveness of the herb, which client assessment should the nurse to complete?
- correct answer Determine sleep patterns
The nurse prepares to administer a scheduled dose of labetaol by mouth to a client with hypertension.
The client's vital signs are temperature 99 F (37.2 C) heart rate 48 beats/minute respirations 16
breaths/minute, and blood pressure 150/90 mmHg. Which action should the nurse take?
- correct answer Withhold the scheduled dose and notify the healthcare provider
To evaluate the effectiveness of a client's prescription of rosuvastatin, which action should the nurse
implement?
- correct answer Evaluate the client's serum cholesterol level results.
