CORRECT WELL DETAILED ANSWERS|LATEST
What are the primary adaptive immune cells? - ANSWER B and T cells
What cells are lymphocytes? - ANSWER NK, B, and T cells
What does the red pulp of the spleen do? - ANSWER erythrocyte (RBC) filtration
What does the white pulp of the spleen do? - ANSWER leukocyte (WBC) filtration
inactivation by Factor H and I results in an opsonin
-NOT a convertase
this is what C - ANSWER ic3b
DAF stands for - ANSWER decay accelerating factor
MCP stands for - ANSWER membrane cofactor protein
inhibit the activity of bacterial proteases - ANSWER alpha2-macroglobulins
1
,are the human version of MAC complex, which creates pores/holes in pathogenic surfaces -
ANSWER defensins
What cell makes up the highest concentration of leukocytes? - ANSWER neutrophils
pus forming - ANSWER pyogenic
fever inducing pyogenic or pyrogenic - ANSWER pyrogenic
CR1 binds to - ANSWER C3b
CR2 binds to - ANSWER C3d
CR3 binds to - ANSWER iC3b
CR4 binds to what on G bacteria - ANSWER LPS on G- bacteria
TLR-3 binds to what virsus - ANSWER dsRNA viruses
TLR-4 binds to what on bacteria - ANSWER LPS on G- bacteria
TLR-5 binds to - ANSWER Flagellin
TLR-7 binds to virsus - ANSWER ssRNA viruses
recognize bacterial cell components 2 N - ANSWER NOD-1/NOD-2
2
,a form of cytokine that directs leukocyte traff - ANSWER chemokines
cytokines
proinflammotory
IL-1,2,3,4,5,6,7,8,9,10,11,12, CX, and T
name the 5 hint:IL-1 - ANSWER proinflammatory mediators ( IL-1, IL-6, IL-12, CXCL8,
and TNF-alpha)
What cells are NOT in germline configuration? - ANSWER mature B and mature T cells
-first Ab produced - ANSWER IgM
Pentameric - ANSWER IgM
activateis complement
which IG ? 2 - ANSWER Igm IgG
can cross mucosal cell via polyg Ig recepor - ANSWER IgM and dimeric IgA
-highest concentration in blood - ANSWER IgG
-good for neutralization/opsonization - ANSWER IgG
crosses placenta via the FcRn/FcRB/Brambell receptor - ANSWER IgG
3
, can be monomeric or dimeric
where are they found? - ANSWER IgA
monomeric=circulation
dimeric=gut
-most abundant in the body
which Ig - ANSWER IgA
-involved in allergic reactions and parasites - ANSWER IgE
-present in serum in low levels: IgG,A,M,E - ANSWER IgE
high affinity for FCeRII found on mast cells, basophils, and activated eosinophils -
ANSWER IgE
-found on the surface of mature, naive B cells (along with IgM) - ANSWER IgD
-complementary determining region and hypervariable loop are synonymous -
ANSWER CDR-X/HV-X
What is the most diverse CDR and HV? - ANSWER CDR3/HV3
Somatic recombination occurs in what2 lymphotcyes? - ANSWER B and T lymphocytes
Somatic hypermutation occurs in what lymphoctye? - ANSWER B lymphocytes
4
What are the primary adaptive immune cells? - ANSWER B and T cells
What cells are lymphocytes? - ANSWER NK, B, and T cells
What does the red pulp of the spleen do? - ANSWER erythrocyte (RBC) filtration
What does the white pulp of the spleen do? - ANSWER leukocyte (WBC) filtration
inactivation by Factor H and I results in an opsonin
-NOT a convertase
this is what C - ANSWER ic3b
DAF stands for - ANSWER decay accelerating factor
MCP stands for - ANSWER membrane cofactor protein
inhibit the activity of bacterial proteases - ANSWER alpha2-macroglobulins
1
,are the human version of MAC complex, which creates pores/holes in pathogenic surfaces -
ANSWER defensins
What cell makes up the highest concentration of leukocytes? - ANSWER neutrophils
pus forming - ANSWER pyogenic
fever inducing pyogenic or pyrogenic - ANSWER pyrogenic
CR1 binds to - ANSWER C3b
CR2 binds to - ANSWER C3d
CR3 binds to - ANSWER iC3b
CR4 binds to what on G bacteria - ANSWER LPS on G- bacteria
TLR-3 binds to what virsus - ANSWER dsRNA viruses
TLR-4 binds to what on bacteria - ANSWER LPS on G- bacteria
TLR-5 binds to - ANSWER Flagellin
TLR-7 binds to virsus - ANSWER ssRNA viruses
recognize bacterial cell components 2 N - ANSWER NOD-1/NOD-2
2
,a form of cytokine that directs leukocyte traff - ANSWER chemokines
cytokines
proinflammotory
IL-1,2,3,4,5,6,7,8,9,10,11,12, CX, and T
name the 5 hint:IL-1 - ANSWER proinflammatory mediators ( IL-1, IL-6, IL-12, CXCL8,
and TNF-alpha)
What cells are NOT in germline configuration? - ANSWER mature B and mature T cells
-first Ab produced - ANSWER IgM
Pentameric - ANSWER IgM
activateis complement
which IG ? 2 - ANSWER Igm IgG
can cross mucosal cell via polyg Ig recepor - ANSWER IgM and dimeric IgA
-highest concentration in blood - ANSWER IgG
-good for neutralization/opsonization - ANSWER IgG
crosses placenta via the FcRn/FcRB/Brambell receptor - ANSWER IgG
3
, can be monomeric or dimeric
where are they found? - ANSWER IgA
monomeric=circulation
dimeric=gut
-most abundant in the body
which Ig - ANSWER IgA
-involved in allergic reactions and parasites - ANSWER IgE
-present in serum in low levels: IgG,A,M,E - ANSWER IgE
high affinity for FCeRII found on mast cells, basophils, and activated eosinophils -
ANSWER IgE
-found on the surface of mature, naive B cells (along with IgM) - ANSWER IgD
-complementary determining region and hypervariable loop are synonymous -
ANSWER CDR-X/HV-X
What is the most diverse CDR and HV? - ANSWER CDR3/HV3
Somatic recombination occurs in what2 lymphotcyes? - ANSWER B and T lymphocytes
Somatic hypermutation occurs in what lymphoctye? - ANSWER B lymphocytes
4
