,3. Thecnurseciscteachingcacpatientcwhocwillcbecdischargedchomecwithcacprescriptioncforcancenteric-
c coatedctablet.cWhichcstatementcbycthecpatientc indicatescunderstandingcofcthecteaching?
a. Icmayccrushcthectabletcandc putcitcincapplesaucectocimprovecabsorption.
b. Icshouldc consumecacidiccfoodsctocenhancecabsorptioncofcthiscmedication.
c. Icshouldc expectc acdelaycinconsetc ofcthecdrugsceffectscafterctakingcthectablet.
d. Icshouldctakecthiscmedicationcwithchigh-
fatcfoodsctocimprovecitscaction.cANS:cC
Enteric-
coatedctabletscresistcdisintegrationcincthecacidiccenvironmentcofcthecstomachcandcdisintegratecwhenct
heycreachcthecsmallcintestine.cThereciscusuallycsomecdelaycinconsetcofcactionscafterctakingcthesecmedi
cations.cEnteric-
coatedctabletscshouldcnotcbeccrushedcorcchewed,cwhichcwouldcaltercthectimecandclocationcofcabsorpti
on.cAcidiccfoodscwillcnotcenhancecthecabsorptioncofcthecmedication.cThecpatientcshouldcnotctoceatchi
gh-fatcfoodcbeforecingestingcancenteric-coatedctablet,cbecausechigh-
fatcfoodscdecreasecthecabsorptioncrate.
DIF:cCOGNITIVEcLEVEL:cApplyingc(Application)cREF:cdmc3cTO
P:cNURSINGcPROCESS:cNursingcIntervention
MSC:cNCLEX:cPhysiologicalcIntegrity:cPharmacologicalcandcParenteralcTherapies
4. Acpatientcwhociscnewlycdiagnosedcwithctypec1cdiabetescmellituscaskscwhycinsulincmustcbecgive
ncbycsubcutaneouscinjectioncinsteadcofcbycmouth.cThecnursecwillcexplaincthatcthisciscbecause
a. absorptioncisc diminishedc bycthecfirst-passceffectscincthecliver.
b. absorptionciscfastercwhencinsulinciscgivencsubcutaneously.
c. digestivecenzymescincthecgastrointestinalctractcpreventcabsorption.
d. thecoralcformcisclesscpredictablecwithcmorecadverseceffects.c
ANS:cC
Insulin,cgrowthchormones,candcothercprotein-
basedcdrugscarecdestroyedcincthecsmallcintestinecbycdigestivecenzymescandcmustcbecgivencparenterall
y.cBecausecinsulinciscdestroyedcbycdigestivecenzymes,citcwouldcnotcmakecitctoctheclivercforcmetabolis
mcwithcacfirst-
passceffect.cSubcutaneousctissuechascfewercbloodcvessels,csocabsorptionciscslowercincsuchctissue.cIns
ulinciscgivencsubcutaneouslycbecausecitciscdesirablectochavecitcabsorbcslowly.
DIF:cCOGNITIVEcLEVEL:cUnderstandingc(Comprehension)cREF:cdmc3cTOP:
c NURSINGcPROCESS:cNursingcIntervention:cPatientcTeaching
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, MSC:cNCLEX:cPhysiologicalcIntegrity:cPharmacologicalcandcParenteralcTherapies
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