PHM 350 Final Exam Questions with Correct Answers Latest Update 2025/2026
Hair loss, GI tract, suppressed bone marrow, liver and kidney damage - Answers Classic side
effects of drugs for cancer therapy
Uses of alkylating agents - Answers Hodgkin's disease, lymphoma, leukemia, ovarian, breast,
testicular cancers, head, neck, lung cancers, neuroblastomas, and brain tumors.
Antimetabolites - Answers Only work effectively in S phase of cell cycle. Substitutes for normal
substrates in DNA.
Methotrexate - Answers Also used for Crohn's disease and ulcerative colitis
Uses of antimetabolites - Answers Breast and colorectal cancers, osteosarcoma, leukemias,
Non-Hodgkin's lymphoma
Mitotic inhibitors - Answers Target microtubules so they cannot separate DNA during replication.
Can cause neuropathy. Vinblastine, vincristine, and paclitaxel.
Steroid hormone agonist - Answers Slows replication
Steroid hormone antagonist - Answers Enhances replication
-tinib - Answers Tyrosine kinase inhibitor
Monoclonal antibody - Answers Drug meant to carry alpha radioisotope directly to cancerous
cells. Do not cause hair loss nor simply target quickly replicating cells.
-mab - Answers Monoclonal antibody
Uticaria - Answers Skin rash
Bacteriostatic - Answers Inhibits bacterial growth
Sulfonamides and trimethoprim - Answers Competitively block bacterial intermediary
metabolism
Penicillins cephalosporins and vancomycin - Answers Cell wall disruption, inhibition of cell wall
synthesis
Erythromycin and clindamycin - Answers Bacteriostatic inhibition of protein synthesis
Tetracyclines and aminoglycosides - Answers Bactericidal inhibition of protein synthesis
Quinolones - Answers Inhibition of DNA/RNA synthesis
Sulfonamide and trimethoprim - Answers Anti folate antibacterials. Bacterial need it to make
purines.
, Gram positive - Answers Type of bacteria sensitive to penicillins
Clavulanate and sulbactam - Answers Additives for penicillins. Penicillinase inhibitors.
Cef- - Answers Cephalosporins
-cycline - Answers Tetracyclines
-mycin - Answers Aminoglycosides
-oxacin - Answers Quinolones
Side effects of estrogen - Answers Nausea, lack of appetite, weight gain, fluid retention,
endometrial hyperplasia, uterine carcinoma, hypertension, stroke, migraines, and breast cancer
VLDL - Answers Major objective in treating hypercholesterolemia is to reduce
Isosorbide dinitrate - Answers Is used by sublingual administration in treatment of an ongoing
anginal episode. NO donor
Thiazide - Answers These diuretics are associated with development of hyperuricemia and gout
Aspirin - Answers Used therapeutically to decrease formation of blood clots
Increased Na in filtrate - Answers Loop diuretics waste potassium through
-glitazone - Answers Effective in treating type 2 diabetes when resistance has developed
Angina - Answers Primarily want to balance oxygen supply and requirements of myocardium
Clonidine - Answers Anti-hypertensive reduces activity of RAS by reducing sympathetic output
from the CNS
Labetalol - Answers Anti-hypertensive drug that reduces blood pressure by direct effects in
heart and RAS
Enalapril and eplerenone - Answers Diuretics that produce hyperkalemia as a side effect
PTU - Answers Used to treat hypothyroidism
Aspirin - Answers Is more effective at causing upset of plasma pH and decreased respiration
Hyperthyroidism - Answers Are treated with radioactive iodine and methimazole
NO - Answers Decreases cardiac work by decreasing TPR
Loop of Henle - Answers Loop diuretics act in
Prednisone - Answers Reduces production of prostaglandins and leukotrienes and reduces
Hair loss, GI tract, suppressed bone marrow, liver and kidney damage - Answers Classic side
effects of drugs for cancer therapy
Uses of alkylating agents - Answers Hodgkin's disease, lymphoma, leukemia, ovarian, breast,
testicular cancers, head, neck, lung cancers, neuroblastomas, and brain tumors.
Antimetabolites - Answers Only work effectively in S phase of cell cycle. Substitutes for normal
substrates in DNA.
Methotrexate - Answers Also used for Crohn's disease and ulcerative colitis
Uses of antimetabolites - Answers Breast and colorectal cancers, osteosarcoma, leukemias,
Non-Hodgkin's lymphoma
Mitotic inhibitors - Answers Target microtubules so they cannot separate DNA during replication.
Can cause neuropathy. Vinblastine, vincristine, and paclitaxel.
Steroid hormone agonist - Answers Slows replication
Steroid hormone antagonist - Answers Enhances replication
-tinib - Answers Tyrosine kinase inhibitor
Monoclonal antibody - Answers Drug meant to carry alpha radioisotope directly to cancerous
cells. Do not cause hair loss nor simply target quickly replicating cells.
-mab - Answers Monoclonal antibody
Uticaria - Answers Skin rash
Bacteriostatic - Answers Inhibits bacterial growth
Sulfonamides and trimethoprim - Answers Competitively block bacterial intermediary
metabolism
Penicillins cephalosporins and vancomycin - Answers Cell wall disruption, inhibition of cell wall
synthesis
Erythromycin and clindamycin - Answers Bacteriostatic inhibition of protein synthesis
Tetracyclines and aminoglycosides - Answers Bactericidal inhibition of protein synthesis
Quinolones - Answers Inhibition of DNA/RNA synthesis
Sulfonamide and trimethoprim - Answers Anti folate antibacterials. Bacterial need it to make
purines.
, Gram positive - Answers Type of bacteria sensitive to penicillins
Clavulanate and sulbactam - Answers Additives for penicillins. Penicillinase inhibitors.
Cef- - Answers Cephalosporins
-cycline - Answers Tetracyclines
-mycin - Answers Aminoglycosides
-oxacin - Answers Quinolones
Side effects of estrogen - Answers Nausea, lack of appetite, weight gain, fluid retention,
endometrial hyperplasia, uterine carcinoma, hypertension, stroke, migraines, and breast cancer
VLDL - Answers Major objective in treating hypercholesterolemia is to reduce
Isosorbide dinitrate - Answers Is used by sublingual administration in treatment of an ongoing
anginal episode. NO donor
Thiazide - Answers These diuretics are associated with development of hyperuricemia and gout
Aspirin - Answers Used therapeutically to decrease formation of blood clots
Increased Na in filtrate - Answers Loop diuretics waste potassium through
-glitazone - Answers Effective in treating type 2 diabetes when resistance has developed
Angina - Answers Primarily want to balance oxygen supply and requirements of myocardium
Clonidine - Answers Anti-hypertensive reduces activity of RAS by reducing sympathetic output
from the CNS
Labetalol - Answers Anti-hypertensive drug that reduces blood pressure by direct effects in
heart and RAS
Enalapril and eplerenone - Answers Diuretics that produce hyperkalemia as a side effect
PTU - Answers Used to treat hypothyroidism
Aspirin - Answers Is more effective at causing upset of plasma pH and decreased respiration
Hyperthyroidism - Answers Are treated with radioactive iodine and methimazole
NO - Answers Decreases cardiac work by decreasing TPR
Loop of Henle - Answers Loop diuretics act in
Prednisone - Answers Reduces production of prostaglandins and leukotrienes and reduces
