EXAM 1 PHM 350 MSU QUESTIONS WITH CORRECT ANSWERS LATEST UPDATE 2025/2026
IN the figures below which has the greater potency?
Drug A
B
C
D - Answers Drug B
Which is used to orthostatic hypotension?
A. isoprotenerenol (ISUPREL)
B.Midodrine (AMANTINE)
C. brimonidine (ALPHAGAN)
D. Albuterol (VENTOILIN)
E. A & C - Answers B. MIDODRINE
Which has the largest therapeutic window?
A: Drug A
B
C
D - Answers Drug D
Isoproterenol (ISUPREL) will decrease blood pressure by:
A: activation of alpha adreoreceptors on blood vessels of the skin and mesentery
B. activation of beta2 adrenoreceptors on the blood vessels of skeletal m
C: blockage of alpha 1 adrenoreceptors on blood vessels of the skin and mesentery
D: Blockage of beta2 adrenoreceptors on the blood vessels of skeletal m
E: none of these - Answers B. activation of beta2 adrenoreceptors on the blood vessels of
skeletal m
Drug A has t1/2 value whihc is half the t1/2 value of Drug B. IN comparing the use of these
drugs, it is likely that Drug A:
, A: is more likely than drug B to produce adverse side efects
B: will be given more frequently than drug B
C: will be given less frequently than Drug B
D: A & B
E. none of the above - Answers B: will be given more frequently than drug B
in the figure below, which statement best fits what you see?
A: fo the response being measures, Drugs A & B are equally potent
B: Drug A is les potent than Drug B
C: Drugs A&B both agonists at te receptor mediating the response being measured
D: If drugs A & B both induce this effect by activating same type of receptor, A have greater
affinity
E: A&C - Answers E: A&C
Bethanechol (URECHOLINE)
A: is choline ester that is also a cholinomimetic
B: has a high affinity for nicotinic cholinergic receptors
C: high affinity for muscuarinic cholinergic receptors
D: is useful therapeutically bc it is substrate for cholinesterases
E: A&C - Answers E: A&C
Liver enzyme, Z, metabolizes drug A. if drug A is administered repeatedly, then the amount of Z
in the liver increased. Consequently.
A: the half ife of drug A wil be increased
B: the hallife of drug B also metabolizes by Z will not be affected
C: half life of all drugs metab by Z will be decreased
D: the rate of metaboism of Drug A will not change
E: A &C - Answers C: half life of all drugs metab by Z will be decreased
therapeutic threshold concentration of a drug
IN the figures below which has the greater potency?
Drug A
B
C
D - Answers Drug B
Which is used to orthostatic hypotension?
A. isoprotenerenol (ISUPREL)
B.Midodrine (AMANTINE)
C. brimonidine (ALPHAGAN)
D. Albuterol (VENTOILIN)
E. A & C - Answers B. MIDODRINE
Which has the largest therapeutic window?
A: Drug A
B
C
D - Answers Drug D
Isoproterenol (ISUPREL) will decrease blood pressure by:
A: activation of alpha adreoreceptors on blood vessels of the skin and mesentery
B. activation of beta2 adrenoreceptors on the blood vessels of skeletal m
C: blockage of alpha 1 adrenoreceptors on blood vessels of the skin and mesentery
D: Blockage of beta2 adrenoreceptors on the blood vessels of skeletal m
E: none of these - Answers B. activation of beta2 adrenoreceptors on the blood vessels of
skeletal m
Drug A has t1/2 value whihc is half the t1/2 value of Drug B. IN comparing the use of these
drugs, it is likely that Drug A:
, A: is more likely than drug B to produce adverse side efects
B: will be given more frequently than drug B
C: will be given less frequently than Drug B
D: A & B
E. none of the above - Answers B: will be given more frequently than drug B
in the figure below, which statement best fits what you see?
A: fo the response being measures, Drugs A & B are equally potent
B: Drug A is les potent than Drug B
C: Drugs A&B both agonists at te receptor mediating the response being measured
D: If drugs A & B both induce this effect by activating same type of receptor, A have greater
affinity
E: A&C - Answers E: A&C
Bethanechol (URECHOLINE)
A: is choline ester that is also a cholinomimetic
B: has a high affinity for nicotinic cholinergic receptors
C: high affinity for muscuarinic cholinergic receptors
D: is useful therapeutically bc it is substrate for cholinesterases
E: A&C - Answers E: A&C
Liver enzyme, Z, metabolizes drug A. if drug A is administered repeatedly, then the amount of Z
in the liver increased. Consequently.
A: the half ife of drug A wil be increased
B: the hallife of drug B also metabolizes by Z will not be affected
C: half life of all drugs metab by Z will be decreased
D: the rate of metaboism of Drug A will not change
E: A &C - Answers C: half life of all drugs metab by Z will be decreased
therapeutic threshold concentration of a drug
