NR293 Pharmacology Exam 1 Questions AND Correct Answers
A nurse is reviewing oral glucocorticosterods with anti-
inflammatory and immunosuppressant effects, which med is
the nurse looking at? - ✔✔Prednisone
A patient is beginning therapy with levothyroxine, when does
it start working? - ✔✔A few weeks
Acetaminophen Contraindications and Interactions - ✔✔Not
taken in the presence of:
- Drug allergy
- LIVER DYSFUNCTION
- Possible liver failure
- G6PD deficiency
- Interactions may occur if taken with alcohol or other drugs
that are hepatotoxic
Acetaminophen Dosage - ✔✔Max dose for healthy adult =
3,000 mg/day
- 2,000 mg/day if liver disease
,Acetaminophen Indications - ✔✔Mild to moderate pain and
fever
Acetaminophen is similar to NSAID's with the exception that it
lacks what? - ✔✔CORRECT
GI irritation
Anti platelet
Anti-inflammatory
WRONG
Analgesic
Adrenal Cortex - ✔✔Secretes corticosteroids
- Glucocorticoids
- Mineralocorticoids (primarily aldosterone)
Adrenal Gland - ✔✔On top of kidney
Adrenal cortex and medulla
,Adrenal Medulla - ✔✔Secretes catecholamines
- Epinephrine
- Norepinephrine
Adverse Effects of Opioid Analgesics - ✔✔- CNS depression
- Respiratory depression
- Nausea/vomiting
- Urinary retention
- Diaphoresis and flushing
- Pupil constriction (miosis)
- Constipation
- Itching
Agonists - ✔✔Bind to an opioid pain receptor in the brain
causing an analgesic response (reduction of pain sensation)
Agonists-Antagonists - ✔✔Bind to a pain receptor causing a
weaker neurologic response than a full agonist (called partial
agonist or mixed agonist)
, Albumin - ✔✔Most common blood protein and CARRIES THE
MAJORITY OF PROTEIN-BOUND DRUG MOLECULES
Antagonists - ✔✔Reverse effects of these drugs on pain
receptors, bind to receptor and exert no response (known as
competitive antagonists)
Antithyroid Drugs - Adverse Effects - ✔✔- LIVER AND BONE
MARROW TOXICITY IS THE MOST DAMAGING/SERIOUS
EFFECT
Antithyroid Drugs - Indications - ✔✔- Treat hyperthyroidism
- PREVENT SURGE IN THYROID HORMONES AFTER SURGICAL
TREATMENT OR DURING RADIOACTIVE IODINE THERAPY
Antithyroid Drugs - Mechanism of Action - ✔✔METHIMAZOLE
& PROPYLTHIOURACIL
- Inhibits the incorporation of IODINE molecules into the
amino acid thyrosine that is required to make T3 and T4
- Propylthiouracil also inhibits the conversion of T4 to T3
during peripheral circulation
A nurse is reviewing oral glucocorticosterods with anti-
inflammatory and immunosuppressant effects, which med is
the nurse looking at? - ✔✔Prednisone
A patient is beginning therapy with levothyroxine, when does
it start working? - ✔✔A few weeks
Acetaminophen Contraindications and Interactions - ✔✔Not
taken in the presence of:
- Drug allergy
- LIVER DYSFUNCTION
- Possible liver failure
- G6PD deficiency
- Interactions may occur if taken with alcohol or other drugs
that are hepatotoxic
Acetaminophen Dosage - ✔✔Max dose for healthy adult =
3,000 mg/day
- 2,000 mg/day if liver disease
,Acetaminophen Indications - ✔✔Mild to moderate pain and
fever
Acetaminophen is similar to NSAID's with the exception that it
lacks what? - ✔✔CORRECT
GI irritation
Anti platelet
Anti-inflammatory
WRONG
Analgesic
Adrenal Cortex - ✔✔Secretes corticosteroids
- Glucocorticoids
- Mineralocorticoids (primarily aldosterone)
Adrenal Gland - ✔✔On top of kidney
Adrenal cortex and medulla
,Adrenal Medulla - ✔✔Secretes catecholamines
- Epinephrine
- Norepinephrine
Adverse Effects of Opioid Analgesics - ✔✔- CNS depression
- Respiratory depression
- Nausea/vomiting
- Urinary retention
- Diaphoresis and flushing
- Pupil constriction (miosis)
- Constipation
- Itching
Agonists - ✔✔Bind to an opioid pain receptor in the brain
causing an analgesic response (reduction of pain sensation)
Agonists-Antagonists - ✔✔Bind to a pain receptor causing a
weaker neurologic response than a full agonist (called partial
agonist or mixed agonist)
, Albumin - ✔✔Most common blood protein and CARRIES THE
MAJORITY OF PROTEIN-BOUND DRUG MOLECULES
Antagonists - ✔✔Reverse effects of these drugs on pain
receptors, bind to receptor and exert no response (known as
competitive antagonists)
Antithyroid Drugs - Adverse Effects - ✔✔- LIVER AND BONE
MARROW TOXICITY IS THE MOST DAMAGING/SERIOUS
EFFECT
Antithyroid Drugs - Indications - ✔✔- Treat hyperthyroidism
- PREVENT SURGE IN THYROID HORMONES AFTER SURGICAL
TREATMENT OR DURING RADIOACTIVE IODINE THERAPY
Antithyroid Drugs - Mechanism of Action - ✔✔METHIMAZOLE
& PROPYLTHIOURACIL
- Inhibits the incorporation of IODINE molecules into the
amino acid thyrosine that is required to make T3 and T4
- Propylthiouracil also inhibits the conversion of T4 to T3
during peripheral circulation
