NEURO NBME EXAM QUESTIONS AND
CORRECT ANSWERS VERIFIED
2025/2026.
Biggest risk factor for ischemic stroke - ANS *HTN*
HASBLED - ANS - Hypertension > 160 systolic
- Age > 65
- Stroke history
- Bleeding history/predisposition
- Labile INR
- Enzymes of liver >3x normal, or bilirubin >2x normal
- Dialysis/transplant
- Meds such as aspirin, clopidogrel, NSAIDs
- Renal disease
Score above 2 results in automatic consideration for alternatives to anticoagulation
CHADVASC - ANS - CHF
- Hypertension
*- Age >75*/ >65
- Diabetes
1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,- Sex
- Vascular disease
*- Thromboembolism hx*
Score of 2 or greater warrants anticoagulation
What do you do if you see evidence of parenchymal bleeding in a symptomatic patient? -
ANS - Control BP and send for Neurosurgery consult
What are some studies that must be done for patients with suspected ischemic stroke? -
ANS - ECG, Echo, Carotid U/s
ECG allows us to identify Afib/Aflutter, which may warrant what kind of medication if the patient
is found to be symptomatic for a potential stroke? - ANS - Warfarin/NOAC without heparin
bridging
Echo allows to identify what in a patient with a suspected stroke? What kind of meds does that
warrant if the patient may have a stroke? - ANS - Thrombus
- Warfarin/NOAC with heparin bridging
NOACs - ANS Direct Xa and PAR-1 antagonists (Vorapaxar)
If a carotid U/S reveals more than 80% occlusion in a patient with a suspected stroke or 70% in a
symptomatic patient, what must be done? - ANS - Endarterectomy unless a stent is
warranted within 2 weeks
Contraindications to TPA - ANS - Recent surgery
- Uncontrolled BP > 180/105
- Recent hx of bleed
- Any previous ICH
2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
, Status Epilepticus (Definition, Go-to treatment) - ANS - > 5 minutes of continuous seizure, OR
>20 minutes before returning to baseline
- Treated with Benzodiazepines
If Benzos do not work for Status, what do you use? - ANS - Fosphenytoin
- Midozolam + Propofol
- Phenobarbital
Go to treatment for generalized seizures - ANS - Valproate
- Lamotrigine
- Levetiracetam
Atonic + Myoclonic seizure treatment - ANS Valproate
Absence seizure treatment - ANS Ethosuximide, valproate, and lamotrigine
Trigeminal neuralgia treatment - ANS Carbamazepine
Parkinsons (Symptoms) - ANS - Cogwheel rigidity
- Bradykinesia
- Pill-rolling tremor
- Shuffling gait
- Postural instability
Parkinson's disease (Medication classes) - ANS - L-Dopa/Carbidopa
- COMT inhibitors (-capones)
- MAOi-B inhibitors (Selegiline)
3 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
CORRECT ANSWERS VERIFIED
2025/2026.
Biggest risk factor for ischemic stroke - ANS *HTN*
HASBLED - ANS - Hypertension > 160 systolic
- Age > 65
- Stroke history
- Bleeding history/predisposition
- Labile INR
- Enzymes of liver >3x normal, or bilirubin >2x normal
- Dialysis/transplant
- Meds such as aspirin, clopidogrel, NSAIDs
- Renal disease
Score above 2 results in automatic consideration for alternatives to anticoagulation
CHADVASC - ANS - CHF
- Hypertension
*- Age >75*/ >65
- Diabetes
1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,- Sex
- Vascular disease
*- Thromboembolism hx*
Score of 2 or greater warrants anticoagulation
What do you do if you see evidence of parenchymal bleeding in a symptomatic patient? -
ANS - Control BP and send for Neurosurgery consult
What are some studies that must be done for patients with suspected ischemic stroke? -
ANS - ECG, Echo, Carotid U/s
ECG allows us to identify Afib/Aflutter, which may warrant what kind of medication if the patient
is found to be symptomatic for a potential stroke? - ANS - Warfarin/NOAC without heparin
bridging
Echo allows to identify what in a patient with a suspected stroke? What kind of meds does that
warrant if the patient may have a stroke? - ANS - Thrombus
- Warfarin/NOAC with heparin bridging
NOACs - ANS Direct Xa and PAR-1 antagonists (Vorapaxar)
If a carotid U/S reveals more than 80% occlusion in a patient with a suspected stroke or 70% in a
symptomatic patient, what must be done? - ANS - Endarterectomy unless a stent is
warranted within 2 weeks
Contraindications to TPA - ANS - Recent surgery
- Uncontrolled BP > 180/105
- Recent hx of bleed
- Any previous ICH
2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
, Status Epilepticus (Definition, Go-to treatment) - ANS - > 5 minutes of continuous seizure, OR
>20 minutes before returning to baseline
- Treated with Benzodiazepines
If Benzos do not work for Status, what do you use? - ANS - Fosphenytoin
- Midozolam + Propofol
- Phenobarbital
Go to treatment for generalized seizures - ANS - Valproate
- Lamotrigine
- Levetiracetam
Atonic + Myoclonic seizure treatment - ANS Valproate
Absence seizure treatment - ANS Ethosuximide, valproate, and lamotrigine
Trigeminal neuralgia treatment - ANS Carbamazepine
Parkinsons (Symptoms) - ANS - Cogwheel rigidity
- Bradykinesia
- Pill-rolling tremor
- Shuffling gait
- Postural instability
Parkinson's disease (Medication classes) - ANS - L-Dopa/Carbidopa
- COMT inhibitors (-capones)
- MAOi-B inhibitors (Selegiline)
3 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
