Pharmacotherapeutics Exam 1 questions well
answered already passed
1. Pharmacokine
How drugs MOVE through body via absorption, distribution,
t- ics
metabolism and excretion.
2. Pharmacodynam- what the drug DOES to the body; mechanism of action
ics
3. Pharmacogene Genetic factors that influence individual responses to a drug
t- ics
4. drug absorption drug movement from GI tract into bloodstream
5. Disintegration Breakdown of oral drug form into smaller particles
6. Dissolution combining small drug particles with liquid to form solution
7. Parenteral drugs drugs absorbed directly into blood stream
8. metabolism body inactivates or bio-transforms drug, LIVER
9. excretion Process by which metabolic wastes are eliminated from the body, KIDNEYS
10. Pinocytosis Cell carries drug across membrane by engulfing drug particles
11. Factors Blood circulation
Affecting Pain
Absorption
Stress
Food texture, fat content,
temperature pH
Route of administration - deltoid more vasculature than glutes
Via portal vein
12. Drug
First pass ettect - attects bioavailability (can increase or
movement
from GI tract decrease it) Bioavailability - percentage of drug available
to liver for activities
1/
65
,Pharmacotherapeutics Exam 1 questions well
answered already passed
13. Absorption route of administration attects about of bioavailability due to first pass ett
2/
65
, Pharmacotherapeutics
Exam 1
14. First pass effect Drug passes through liver before entering systemic circulation which attec
bioavailability
15. Bioavailability Amount of drug that reaches the systemic circulation
16. Drug distribution Part of pharmacokinetics; has to reach the site where it needs to take
action
17. Lipophilic drugs must be this to cross the blood-brain barrier.
Ex: narcotics
18. Half-life (t 1/2) the time it takes for one half of the drug concentration to be eliminated
Long time = drug requires loading
dose 3 to 5 to saturate
biologic system
19. Therapeutic range/amount of medication you can take to produce a therapeutic ettect
in- dex without risk of toxicity
Low: narrow margin of
safety High: Wide margin
of safety
20. Agonist drugs that produce a response
21. Antagonist drugs that block a response
22. Nonspecifi drugs that attect multiple sites/ receptors
c/
Nonselectiv
e
3/
65
, Pharmacotherapeutics
Exam 1
23. Onset Time it takes a drug to reach minimum ettective concentration
24. Peak Time of highest plasma drug concentration and shows rate of
absorption best to test 1 hour after administration
4/
65
answered already passed
1. Pharmacokine
How drugs MOVE through body via absorption, distribution,
t- ics
metabolism and excretion.
2. Pharmacodynam- what the drug DOES to the body; mechanism of action
ics
3. Pharmacogene Genetic factors that influence individual responses to a drug
t- ics
4. drug absorption drug movement from GI tract into bloodstream
5. Disintegration Breakdown of oral drug form into smaller particles
6. Dissolution combining small drug particles with liquid to form solution
7. Parenteral drugs drugs absorbed directly into blood stream
8. metabolism body inactivates or bio-transforms drug, LIVER
9. excretion Process by which metabolic wastes are eliminated from the body, KIDNEYS
10. Pinocytosis Cell carries drug across membrane by engulfing drug particles
11. Factors Blood circulation
Affecting Pain
Absorption
Stress
Food texture, fat content,
temperature pH
Route of administration - deltoid more vasculature than glutes
Via portal vein
12. Drug
First pass ettect - attects bioavailability (can increase or
movement
from GI tract decrease it) Bioavailability - percentage of drug available
to liver for activities
1/
65
,Pharmacotherapeutics Exam 1 questions well
answered already passed
13. Absorption route of administration attects about of bioavailability due to first pass ett
2/
65
, Pharmacotherapeutics
Exam 1
14. First pass effect Drug passes through liver before entering systemic circulation which attec
bioavailability
15. Bioavailability Amount of drug that reaches the systemic circulation
16. Drug distribution Part of pharmacokinetics; has to reach the site where it needs to take
action
17. Lipophilic drugs must be this to cross the blood-brain barrier.
Ex: narcotics
18. Half-life (t 1/2) the time it takes for one half of the drug concentration to be eliminated
Long time = drug requires loading
dose 3 to 5 to saturate
biologic system
19. Therapeutic range/amount of medication you can take to produce a therapeutic ettect
in- dex without risk of toxicity
Low: narrow margin of
safety High: Wide margin
of safety
20. Agonist drugs that produce a response
21. Antagonist drugs that block a response
22. Nonspecifi drugs that attect multiple sites/ receptors
c/
Nonselectiv
e
3/
65
, Pharmacotherapeutics
Exam 1
23. Onset Time it takes a drug to reach minimum ettective concentration
24. Peak Time of highest plasma drug concentration and shows rate of
absorption best to test 1 hour after administration
4/
65
